Search Results - "Giraud, Emilie"
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Mosquito‐bacteria interactions during larval development trigger metabolic changes with carry‐over effects on adult fitness
Published in Molecular ecology (01-03-2022)“…In animals with distinct life stages such as holometabolous insects, adult phenotypic variation is often shaped by the environment of immature stages,…”
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Role of PDZ-binding motif from West Nile virus NS5 protein on viral replication
Published in Scientific reports (05-02-2021)“…West Nile virus (WNV) is a Flavivirus, which can cause febrile illness in humans that may progress to encephalitis. Like any other obligate intracellular…”
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Quantifying Leishmania Metacyclic Promastigotes from Individual Sandfly Bites Reveals the Efficiency of Vector Transmission
Published in Communications biology (28-02-2019)“…Predicting how Leishmania will respond to control efforts requires an understanding of their transmission strategy. Using real-time quantitative PCR to…”
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Leishmania proteophosphoglycans regurgitated from infected sand flies accelerate dermal wound repair and exacerbate leishmaniasis via insulin-like growth factor 1-dependent signalling
Published in PLoS pathogens (01-01-2018)“…Leishmania parasites are transmitted to vertebrate hosts by female phlebotomine sand flies as they bloodfeed by lacerating the upper capillaries of the dermis…”
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5
RNA Extraction from Ears and Draining Lymph Nodes of Mice Infected with Leishmania amazonensis
Published in Bio-protocol (05-06-2020)“…Parasites of the genus infect the mammalian hosts, including mice and humans and cause cutaneous or visceral leishmaniasis depending upon the parasite species…”
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Enhanced neutralization escape to therapeutic monoclonal antibodies by SARS-CoV-2 omicron sub-lineages
Published in iScience (21-04-2023)“…The landscape of SARS-CoV-2 variants dramatically diversified with the simultaneous appearance of multiple subvariants originating from BA.2, BA.4, and BA.5…”
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Osteopontin in the host response to Leishmania amazonensis
Published in BMC microbiology (08-02-2019)“…Leishmania (L.) spp are intracellular eukaryotic parasites responsible for cutaneous or visceral leishmaniasis, replicating predominantly in macrophages (MF)…”
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High-Content RNAi Phenotypic Screening Unveils the Involvement of Human Ubiquitin-Related Enzymes in Late Cytokinesis
Published in Cells (Basel, Switzerland) (30-11-2022)“…CEP55 is a central regulator of late cytokinesis and is overexpressed in numerous cancers. Its post-translationally controlled recruitment to the midbody is…”
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High-throughput screening identifies broad-spectrum Coronavirus entry inhibitors
Published in iScience (21-06-2024)“…The COVID-19 pandemic highlighted the need for antivirals against emerging coronaviruses (CoV). Inhibiting spike (S) glycoprotein-mediated viral entry is a…”
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Reprogramming neutral lipid metabolism in mouse dendritic leucocytes hosting live Leishmania amazonensis amastigotes
Published in PLoS neglected tropical diseases (01-06-2013)“…After loading with live Leishmania (L) amazonensis amastigotes, mouse myeloid dendritic leucocytes/DLs are known to undergo reprogramming of their immune…”
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Distinct transcriptional signatures of bone marrow-derived C57BL/6 and DBA/2 dendritic leucocytes hosting live Leishmania amazonensis amastigotes
Published in PLoS neglected tropical diseases (01-12-2012)“…The inoculation of a low number (10(4)) of L. amazonensis metacyclic promastigotes into the dermis of C57BL/6 and DBA/2 mouse ear pinna results in distinct…”
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Type 1 diabetes and parasite infection: An exploratory study in NOD mice
Published in PloS one (22-10-2024)“…Microorganisms have long been suspected to influence the outcome of immune-related syndromes, particularly autoimmune diseases. Type 1 diabetes (T1D) results…”
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Characterizing Mosquito Biting Behavior Using the BiteOscope
Published in Cold Spring Harbor protocols (01-07-2023)“…The biteOscope enables the high-resolution monitoring and video recording of blood-feeding mosquitoes. Mosquito biting is induced by combining host cues, an…”
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Characterizing Mosquito Biting Behavior at High Resolution
Published in Cold Spring Harbor protocols (01-07-2023)“…Blood feeding is a critical event in the life cycle of female mosquitoes. In addition to providing nutrients to the mosquito, blood feeding facilitates the…”
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Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2
Published in The Journal of experimental medicine (04-07-2022)“…Memory B-cell and antibody responses to the SARS-CoV-2 spike protein contribute to long-term immune protection against severe COVID-19, which can also be…”
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Glycan–glycan interactions determine Leishmania attachment to the midgut of permissive sand fly vectors
Published in Chemical science (Cambridge) (28-10-2020)“…Direct glycan–glycan interactions are increasingly implicated in survival and pathogenicity of bacteria. Here, we show that they can be exploited by protozoan…”
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Metabolic, Immune, and Gut Microbial Signals Mount a Systems Response to Leishmania major Infection
Published in Journal of proteome research (02-01-2015)“…Parasitic infections such as leishmaniasis induce a cascade of host physiological responses, including metabolic and immunological changes. Infection with…”
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Elucidating and characterizing the dynamic biological processes that account for the sustainability of Leishmania populations
Published in Médecine tropicale et santé internationale (30-06-2023)“…To attempt resolving this issue accurately, it was necessary to anchor our experimental approaches in the observations and pioneering work of our predecessors,…”
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Reprogramming Neutral Lipid Metabolism in Mouse Dendritic Leucocytes Hosting Live Leishmania amazonensis Amastigotes: e2276
Published in PLoS neglected tropical diseases (01-06-2013)“…Background After loading with live Leishmania (L) amazonensis amastigotes, mouse myeloid dendritic leucocytes/DLs are known to undergo reprogramming of their…”
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A combined luciferase-expressing Leishmania imaging/RT-qPCR assay provides new insights into the sequential bilateral processes deployed in the ear pinna of C57BL/6 mice
Published in Parasitology international (01-02-2014)“…Abstract Leishmania / L. major was identified as the etiological agent of human localized cutaneous leishmaniasis. L. major metacyclic promastigotes/MP – the…”
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