Search Results - "Girard, Mathilde"
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Complementarity and redundancy of IL-22-producing innate lymphoid cells
Published in Nature immunology (01-02-2016)“…The function of group 3 innate lymphoid cells (ILC3 cells) is still being determined. Vivier and colleagues describe the development of ILC3 subsets and show…”
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β2-adrenergic signals downregulate the innate immune response and reduce host resistance to viral infection
Published in The Journal of experimental medicine (06-04-2020)“…In humans, psychological stress has been associated with a higher risk of infectious illness. However, the mechanisms by which the stress pathway interferes…”
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IL-10 suppression of NK/DC crosstalk leads to poor priming of MCMV-specific CD4 T cells and prolonged MCMV persistence
Published in PLoS pathogens (01-08-2012)“…IL-10 is an anti-inflammatory cytokine that regulates the extent of host immunity to infection by exerting suppressive effects on different cell types. Herpes…”
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The immunological functions of the Appendix: An example of redundancy?
Published in Seminars in immunology (01-04-2018)“…•The Appendix appeared several independent times and is conserved in evolution.•The Appendix is rich in lymphoid tissue and contributes to intestinal…”
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The Role of Human Leukocyte Antigen Matching in the Development of Multiethnic "Haplobank" of Induced Pluripotent Stem Cell Lines
Published in Stem cells (Dayton, Ohio) (01-02-2012)“…Among the tools of regenerative medicine, induced pluripotent stem cells (iPSCs) are interesting because the donor genotype can be selected. The construction…”
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Transforming growth factor-β and Notch ligands act as opposing environmental cues in regulating the plasticity of type 3 innate lymphoid cells
Published in Science signaling (03-05-2016)“…Group 3 innate lymphoid cells (ILC3s) are composed of subsets that are either positive or negative for the natural cytotoxicity receptor (NCR) NKp46 (encoded…”
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Quality control guidelines for clinical-grade human induced pluripotent stem cell lines
Published in Regenerative medicine (01-10-2018)“…Use of clinical-grade human induced pluripotent stem cell (iPSC) lines as a starting material for the generation of cellular therapeutics requires…”
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IL-10 controls dendritic cell–induced T-cell reactivation in the skin to limit contact hypersensitivity
Published in Journal of allergy and clinical immunology (01-01-2012)“…Background IL-10 is a pleiotropic cytokine and potent negative regulator of both innate and adaptive immune responses. Consequently, IL-10–deficient (IL-10−/−…”
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TGF-beta is required to maintain the pool of immature Langerhans cells in the epidermis
Published in The Journal of immunology (1950) (15-09-2010)“…The pivotal role of TGF-beta in Langerhans cell (LC) development has been previously established in TGF-beta-deficient mice, which lack epidermal LCs. As to…”
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Optimized Protocol for Characterization of Mouse Gut Innate Lymphoid Cells
Published in Frontiers in immunology (30-11-2020)“…Since their discovery, innate lymphoid cells (ILCs) have gradually been gaining greater relevance in the field of immunology due to their multiple functions in…”
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High-Dimensional Single-Cell Analysis Identifies Organ-Specific Signatures and Conserved NK Cell Subsets in Humans and Mice
Published in Immunity (Cambridge, Mass.) (20-11-2018)“…Natural killer (NK) cells are innate lymphoid cells (ILCs) involved in antimicrobial and antitumoral responses. Several NK cell subsets have been reported in…”
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Unique Preservation of Neural Cells in Hutchinson- Gilford Progeria Syndrome Is Due to the Expression of the Neural-Specific miR-9 MicroRNA
Published in Cell reports (Cambridge) (26-07-2012)“…One puzzling observation in patients affected with Hutchinson-Gilford progeria syndrome (HGPS), who overall exhibit systemic and dramatic premature aging, is…”
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IL-10 control of CD11c+ myeloid cells is essential to maintain immune homeostasis in the small and large intestine
Published in Oncotarget (31-05-2016)“…Although IL-10 promotes a regulatory phenotype of CD11c+ dendritic cells and macrophages in vitro, the role of IL-10 signaling in CD11c+ cells to maintain…”
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Emissions of VOCs From Polymer-Based Consumer Products: From Emission Data of Real Samples to the Assessment of Inhalation Exposure
Published in Frontiers in public health (14-08-2019)“…The development of consumerism led to an increase in toy production. Such consumer products may contain non-intentionally added toxic substances that can emit…”
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IL-10 signaling in dendritic cells attenuates anti-Leishmania major immunity without affecting protective memory responses
Published in Journal of investigative dermatology (01-11-2015)Get full text
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Distinct Waves from the Hemogenic Endothelium Give Rise to Layered Lymphoid Tissue Inducer Cell Ontogeny
Published in Cell reports (Cambridge) (11-08-2020)“…During embryogenesis, lymphoid tissue inducer (LTi) cells are essential for lymph node organogenesis. These cells are part of the innate lymphoid cell (ILC)…”
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IL-10 control of dendritic cells in the skin
Published in Oncoimmunology (01-03-2013)“…Interleukin-10 (IL-10) is a potent immunomodulatory cytokine, whose cellular targets have not yet been precisely identified. Dendritic cell (DC)-specific IL-10…”
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Methylation and Transcripts Expression at the Imprinted GNAS Locus in Human Embryonic and Induced Pluripotent Stem Cells and Their Derivatives
Published in Stem cell reports (09-09-2014)“…Data from the literature indicate that genomic imprint marks are disturbed in human pluripotent stem cells (PSCs). GNAS is an imprinted locus that produces one…”
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SOX10 mutations in chronic intestinal pseudo-obstruction suggest a complex physiopathological mechanism
Published in Human genetics (01-08-2002)“…The type IV Waardenburg syndrome (WS4), also referred to as Shah-Waardenburg syndrome or Waardenburg-Hirschsprung disease, is characterised by the association…”
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Connexin 32 promoter P2 mutations: A mechanism of peripheral nerve dysfunction
Published in Annals of neurology (01-11-2004)“…We identified a large Charcot–Marie–Tooth disease family with a novel mutation in the Connexin 32 (Cx32) P2 promoter region at position −526bp. This mutation…”
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