Search Results - "Girão, Roberson Donola"
-
1
N6-methyltubercidin gives sterile cure in a cutaneous Leishmania amazonensis mouse model
Published in Parasitology (01-04-2024)“…Leishmania is a trypanosomatid parasite that causes skin lesions in its cutaneous form. Current therapies rely on old and expensive drugs, against which the…”
Get full text
Journal Article -
2
N6-modification of 7-Deazapurine nucleoside analogues as Anti-Trypanosoma cruzi and anti-Leishmania agents: Structure-activity relationship exploration and In vivo evaluation
Published in European journal of medicinal chemistry (05-03-2022)“…Chagas disease and leishmaniasis are two poverty-related neglected tropical diseases that cause high mortality and morbidity. Current treatments suffer from…”
Get full text
Journal Article -
3
7-Aryl-7-deazapurine 3′-deoxyribonucleoside derivative as a novel lead for Chagas’ disease therapy: in vitro and in vivo pharmacology
Published in JAC-antimicrobial resistance (01-12-2021)“…Abstract Background The protozoan Trypanosoma cruzi is auxotrophic for purines and causes Chagas’ disease (CD), a neglected illness affecting >6 million…”
Get full text
Journal Article -
4
N 6 -methyltubercidin gives sterile cure in a cutaneous Leishmania amazonensis mouse model
Published in Parasitology (01-04-2024)“…is a trypanosomatid parasite that causes skin lesions in its cutaneous form. Current therapies rely on old and expensive drugs, against which the parasites…”
Get full text
Journal Article -
5
-
6
N 6 -modification of 7-Deazapurine nucleoside analogues as Anti-Trypanosoma cruzi and anti-Leishmania agents: Structure-activity relationship exploration and In vivo evaluation
Published in European journal of medicinal chemistry (05-03-2022)“…Chagas disease and leishmaniasis are two poverty-related neglected tropical diseases that cause high mortality and morbidity. Current treatments suffer from…”
Get full text
Journal Article