Search Results - "Giovenzana, Giovanni"
-
1
A Concise and Safe Synthesis of 1,2,3‐Propanetriamine (PTA)
Published in European journal of organic chemistry (15-03-2022)“…1,2,3‐Propanetriamine (PTA) is the simplest aliphatic vicinal triamine, a key compound in coordination chemistry and for the preparation of polymers and for…”
Get full text
Journal Article -
2
Improving Zonisamide Manufacturing: Insights into Stereochemistry and Mechanisms for Continuous Optimization
Published in European journal of organic chemistry (04-11-2024)“…Zonisamide is a heterocyclic sulfonamide widely employed as anticonvulsant. In this work, we report an efficient process for the preparation of zonisamide,…”
Get full text
Journal Article -
3
TRASUTA: The Effect of the Structural Rigidity of a Mesocyclic AAZTA-like Chelating Agent on the Thermodynamic, Kinetic, and Structural Properties of Some Divalent Metal and Ga 3+ Complexes
Published in Inorganic chemistry (08-07-2024)“…Mesocyclic chelating agents such as AAZTA and its derivatives have been recently reported to overcome the relatively low thermodynamic stability of metal…”
Get full text
Journal Article -
4
TRASUTA: The Effect of the Structural Rigidity of a Mesocyclic AAZTA-like Chelating Agent on the Thermodynamic, Kinetic, and Structural Properties of Some Divalent Metal and Ga3+ Complexes
Published in Inorganic chemistry (08-07-2024)“…Mesocyclic chelating agents such as AAZTA and its derivatives have been recently reported to overcome the relatively low thermodynamic stability of metal…”
Get full text
Journal Article -
5
[Gd(HB‐DO3A)]: Equilibrium, Dissociation Kinetic and Structural Differences in a Simple Homolog of [Gd(HP‐DO3A)] (Prohance®)
Published in Chemistry : a European journal (17-05-2024)“…[Gd(HP‐DO3A)] (gadoteridol) as an active compound of ProHance® is a widely employed contrast agent in clinical MRI scans in the last 30 years. Recent concerns…”
Get full text
Journal Article -
6
Influence of Silicodactyly in the Preparation of Hybrid Materials
Published in Molecules (Basel, Switzerland) (28-02-2019)“…The organic⁻inorganic hybrid materials have attracted great attention due to their improved or unusual properties that open promising applications in different…”
Get full text
Journal Article -
7
Equilibrium and Kinetic Properties of the Lanthanoids(III) and Various Divalent Metal Complexes of the Heptadentate Ligand AAZTA
Published in Chemistry : a European journal (02-02-2009)“…Towards improved kinetic stability: A detailed account of the complexation properties of the ligand…”
Get full text
Journal Article -
8
Boosting Bismuth(III) Complexation for Targeted α‐Therapy (TAT) Applications with the Mesocyclic Chelating Agent AAZTA
Published in Angewandte Chemie International Edition (24-10-2022)“…Targeted α therapy (TAT) is a promising tool in the therapy of cancer. The radionuclide 213BiIII shows favourable physical properties for this application, but…”
Get full text
Journal Article -
9
Relaxometric and Modelling Studies of the Binding of a Lipophilic Gd-AAZTA Complex to Fatted and Defatted Human Serum Albumin
Published in Chemistry : a European journal (01-01-2007)“…A new lipophilic gadolinium chelate consisting of a long aliphatic chain bound to the AAZTA coordination cage (Gd‐AAZTAC17) has been synthesised. It possesses…”
Get full text
Journal Article -
10
Recent Advances in Bifunctional Paramagnetic Chelates for MRI
Published in Israel journal of chemistry (01-09-2017)“…Magnetic resonance imaging (MRI) is a non‐invasive diagnostic modality routinely employed in modern clinical medicine to collect images of the internal organs…”
Get full text
Journal Article -
11
The Legacy of AAZTA—Synthesis and Coordination Chemistry of Two AAZTA Structural Analogs
Published in Inorganics (01-09-2024)“…AAZTA (6-amino-6-methylperhydro-1,4-diazepinetetraacetic acid) is a mesocyclic chelating agent forming stable complexes with several metal ions. Over the past…”
Get full text
Journal Article -
12
An enzymatic approach to bifunctional chelating agents
Published in Organic & biomolecular chemistry (21-09-2014)“…Bifunctional chelating agents (BFCAs) combine the complexing properties of a multidentate ligand with the presence of a free reactive functional group, mainly…”
Get more information
Journal Article -
13
PIDAZTA: Structurally Constrained Chelators for the Efficient Formation of Stable Gallium‐68 Complexes at Physiological pH
Published in Chemistry : a European journal (09-08-2019)“…Two structurally constrained chelators based on a fused bicyclic scaffold, 4‐amino‐4‐methylperhydro‐pyrido[1,2‐a][1,4]diazepin‐N,N′,N′‐triacetic acids…”
Get full text
Journal Article -
14
Unprecedented Formation of 2,5‐Diaminoquinones from the Reaction of Vanillin with Secondary Amines in Aerobic Conditions
Published in European journal of organic chemistry (09-01-2020)“…Vanillin is widely used as a flavoring agent in foods, perfumes and in several other applications. Even if huge amounts of vanillin are annually employed in…”
Get full text
Journal Article -
15
Lower Denticity Leading to Higher Stability: Structural and Solution Studies of Ln(III)–OBETA Complexes
Published in Inorganic chemistry (01-12-2014)“…The heptadentate ligand OBETA (2,2′-oxybis(ethylamine)-N,N,N′,N′-tetraacetic acid) was reported to form complexes with Ln3+ ions more stable than those formed…”
Get full text
Journal Article -
16
Difluprednate: More than meets the eye
Published in Journal of pharmaceutical and biomedical analysis (05-01-2015)“…The rich structural and thermal behavior of three difluprednate polymorphs has been clarified, and the validity of previous complex and sometimes contradicting…”
Get full text
Journal Article -
17
Dual MRI-SPECT agent for pH-mapping
Published in Chemical communications (Cambridge, England) (07-02-2011)“…A new dual MRI/SPECT pH-responsive agent where the SPECT active moiety acts as reporter of the concentration making it possible to exploit the responsiveness…”
Get more information
Journal Article -
18
Lower Ligand Denticity Leading to Improved Thermodynamic and Kinetic Stability of the Gd3+ Complex: The Strange Case of OBETA
Published in Chemistry : a European journal (18-06-2012)“…OBETA, OBETA, you bet: Thermodynamic and kinetic measurements show an apparent paradox. The stability of complexes of lanthanide trivalent ions is higher with…”
Get full text
Journal Article -
19
Equilibrium, Kinetic and Structural Studies of AAZTA Complexes with Ga3+, In3+ and Cu2
Published in European journal of inorganic chemistry (01-01-2013)“…A detailed study of the structures, thermodynamic stabilities and kinetics of the dissociation of Ga3+, In3+ and Cu2+ complexes formed with the heptadentate…”
Get full text
Journal Article -
20
Synthesis of bifunctional chelating agents based on mono and diphosphonic derivatives of diethylenetriaminepentaacetic acid
Published in Tetrahedron (12-08-2014)“…Bifunctional chelating agents (BFCAs) are small molecules containing a chelating unit, able to strongly coordinate a metal ion, and a reactive functional…”
Get full text
Journal Article