Search Results - "Giordano, Pasqualina"
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Evaluation of the Molecular Landscape in PD-L1 Positive Metastatic NSCLC: Data from Campania, Italy
Published in International journal of molecular sciences (01-08-2022)“…Background: Immune-checkpoint inhibitors (ICIs) have increased and improved the treatment options for patients with non-oncogene-addicted advanced stage…”
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2
Afatinib: An overview of its clinical development in non-small-cell lung cancer and other tumors
Published in Critical reviews in oncology/hematology (01-01-2016)“…Abstract Afatinib is an oral, irreversible, tyrosine kinase inhibitor (TKI) of EGFR, HER2 and HER4. According to phase I studies, the recommended dose of…”
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3
Vasari Scoring System in Discerning between Different Degrees of Glioma and IDH Status Prediction: A Possible Machine Learning Application?
Published in Journal of imaging (24-03-2023)“…(1) The aim of our study is to evaluate the capacity of the Visually AcceSAble Rembrandt Images (VASARI) scoring system in discerning between the different…”
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4
Epigenetic Regulation in Melanoma: Facts and Hopes
Published in Cells (Basel, Switzerland) (11-08-2021)“…Cutaneous melanoma is a lethal disease, even when diagnosed in advanced stages. Although recent progress in biology and treatment has dramatically improved…”
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Assessment of therapy response to Regorafenib by 18F-DOPA-PET/CT in patients with recurrent high-grade gliomas: a case series
Published in Clinical and translational imaging : reviews in nuclear medicine and molecular imaging (01-06-2021)“…Purpose Regorafenib (REG) has been recently approved for the treatment of relapsed glioblastoma. Contrast-enhanced (CE) magnetic resonance (MR) imaging…”
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Combining anti-Epidermal Growth Factor Receptor (EGFR) and anti-angiogenic strategies in advanced NSCLC: we should have known better
Published in Current pharmaceutical design (01-01-2014)“…Drugs directed against Epidermal Growth Factor Receptor (EGFR), namely tyrosine kinase inhibitors erlotinib and gefitinib, and anti-angiogenic agents, namely…”
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7
Integrated therapeutic approaches in the treatment of locally advanced non-small cell lung cancer
Published in Anti-cancer agents in medicinal chemistry (01-07-2013)“…Treatment of locally advanced non-small cell lung cancer (NSCLC) remains a significant challenge for oncologists, despite progress made in recent years in…”
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Time spent for activation of non-profit studies in oncology in Italy
Published in PloS one (29-07-2010)“…The aim of this paper is to describe the time spent to activate oncological non-profit clinical trials promoted in Italy by the National Cancer Institute of…”
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Immune Checkpoint Inhibitors in Hepatocellular Carcinoma: Current Status and Novel Perspectives
Published in Cancers (18-10-2020)“…Immune checkpoint inhibitors (ICIs) represent a promising treatment for many kinds of cancers, including hepatocellular carcinoma (HCC). The rationale for…”
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10
Progress and challenges in the treatment of small cell lung cancer
Published in Medical oncology (Northwood, London, England) (01-06-2017)“…Small cell lung cancer (SCLC) is a very aggressive malignancy characterized by high cellular proliferation and early metastatic spread. In fact, although SCLC…”
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Treatment of small cell lung cancer
Published in Critical reviews in oncology/hematology (01-09-2014)“…Abstract Treatment of small cell lung cancer (SCLC) remains a significant challenge for the oncologists. Attempts to improve the results of first-line…”
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12
Case report: Tracing in parallel the salivary and gut microbiota profiles to assist Larotrectinib anticancer treatment for NTRK fusion–positive glioblastoma
Published in Frontiers in oncology (20-11-2024)“…Oncotherapy can shape intestinal microbiota, which, in turn, may influence therapy effectiveness. Furthermore, microbiome signatures during treatments can be…”
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13
Early PET/CT scan is more effective than RECIST in predicting outcome of patients with liver metastases from colorectal cancer treated with preoperative chemotherapy plus bevacizumab
Published in Journal of Nuclear Medicine (01-12-2013)“…Markers predictive of treatment effect might be useful to improve the treatment of patients with metastatic solid tumors. Particularly, early changes in tumor…”
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14
Randomized phase III trial of gemcitabine and cisplatin vs. gemcitabine alone in patients with advanced non-small cell lung cancer and a performance status of 2: The CAPPA-2 study
Published in Lung cancer (Amsterdam, Netherlands) (01-07-2013)“…Abstract Platinum-based chemotherapy is the standard treatment for patients with advanced non-small cell lung cancer (NSCLC), but the evidence of its efficacy…”
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15
Bone Metastases from Gastric Cancer: What We Know and How to Deal with Them
Published in Journal of clinical medicine (19-04-2021)“…Gastric cancer (GC) is the third cause of cancer-related death worldwide; the prognosis is poor especially in the case of metastatic disease. Liver, lymph…”
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16
The role of radiation therapy and systemic therapies in elderly with breast cancer
Published in Translational cancer research (01-01-2020)“…The focus of this review deals with the management of elderly patients with early stage breast cancer, discussing the role of systemic therapies [endocrine…”
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Multicenter Single-Arm, Two-Stage Phase 2 Study of Panitumumab in Patients With Cetuximab-Refractory Metastatic Colorectal Cancer: The PACER Trial
Published in Clinical colorectal cancer (01-12-2020)“…To assess whether panitumumab is active in patients with cetuximab-refractory metastatic colorectal cancer (mCRC). Eligible patients had pretreated RAS…”
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How can we improve prognostic models in renal cell carcinoma?
Published in Expert opinion on pharmacotherapy (01-06-2015)“…The therapeutic improvements in renal cell carcinoma brought about by the transition from the 'cytokine era' to the 'targeted agents era', have not affected…”
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New biological treatments for gynecological tumors: focus on angiogenesis
Published in Expert opinion on biological therapy (01-03-2014)“…Gynecological tumors are a group of heterogeneous malignancies, with only modest results having been observed thus far with chemotherapy in advanced disease…”
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Cetuximab in non-small-cell lung cancer
Published in Expert review of anticancer therapy (01-02-2012)“…Cetuximab is a chimeric human-mouse anti-EGF receptor monoclonal antibody. In Phase I studies, no dose-limiting toxicities were observed with cetuximab as a…”
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