Search Results - "Giordano, Courtney R"

Catalase therapy corrects oxidative stress-induced pathophysiology in incipient diabetic retinopathy by Giordano, Courtney R, Roberts, Robin, Krentz, Kendra A, Bissig, David, Talreja, Deepa, Kumar, Ashok, Terlecky, Stanley R, Berkowitz, Bruce A

“…Preclinical studies have highlighted retinal oxidative stress in the pathogenesis of diabetic retinopathy. We evaluated whether a treatment designed to enhance…”
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Peroxisomes, cell senescence, and rates of aging by Giordano, Courtney R., Terlecky, Stanley R.

“…The peroxisome is functionally integrated into an exquisitely complex network of communicating endomembranes which is only beginning to be appreciated. Despite…”
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Microglial Inflammation and Cognitive Dysfunction in Comorbid Rat Models of Striatal Ischemic Stroke and Alzheimer’s Disease: Effects of Antioxidant Catalase-SKL on Behavioral and Cellular Pathology by MacKenzie, Jennifer L., Ivanova, Nadezda, Nell, Hayley J., Giordano, Courtney R., Terlecky, Stanley R., Agca, Cansu, Agca, Yuksel, Walton, Paul A., Whitehead, Shawn N., Cechetto, David F.

“…•Brain ischemia in amyloid-β25–35 injected rat increases basal forebrain microgliosis.•Increased striatal microglia inflammation in transgenic rat with…”
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Amyloid-beta neuroprotection mediated by a targeted antioxidant by Giordano, Courtney R., Terlecky, Laura J., Bollig-Fischer, Aliccia, Walton, Paul A., Terlecky, Stanley R.

“…Amyloid-beta (Aβ)-induced neurotoxicity is a major contributor to the pathologies associated with Alzheimer's disease (AD). The formation of reactive oxygen…”
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Targeted Antioxidant, Catalase–SKL, Reduces Beta‐Amyloid Toxicity in the Rat Brain by Nell, Hayley J., Au, Jennifer. L., Giordano, Courtney R., Terlecky, Stanley R., Walton, Paul A., Whitehead, Shawn N., Cechetto, David.F.

“…Accumulation of beta‐amyloid (Aβ) in the brain has been implicated as a major contributor to the cellular pathology and cognitive impairment observed in…”
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A targeted enzyme approach to sensitization of tyrosine kinase inhibitor-resistant breast cancer cells by Giordano, Courtney R., Mueller, Kelly L., Terlecky, Laura J., Krentz, Kendra A., Bollig-Fischer, Aliccia, Terlecky, Stanley R., Boerner, Julie L.

“…Gefitinib is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) of potential use in patients with breast cancer. Unfortunately, in…”
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Peroxisomes,oxidative stress,and inflammation by Terlecky, Stanley R, Terlecky, Laura J, Giordano, Courtney R

“…Peroxisomes are intracellular organelles mediating a wide variety of biosynthetic and biodegradative reactions.Included among these are the metabolism of…”
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Effects of altering the peroxisomal redox state in models of degenerative disease by Giordano, Courtney R

“…Peroxisomes are important regulators of cellular redox balance and function as a signaling platform to regulate anti-aging metabolic and communication…”
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Effects of altering the peroxisomal redox state in models of degenerative disease by Giordano, Courtney R

“…Peroxisomes are important regulators of cellular redox balance and function as a signaling platform to regulate anti-aging metabolic and communication…”
Get full text