Search Results - "Giodini, Alessandra"

A Role for the Endoplasmic Reticulum Protein Retrotranslocation Machinery during Crosspresentation by Dendritic Cells by Ackerman, Anne L., Giodini, Alessandra, Cresswell, Peter

“…Crosspresentation of exogenous antigens (Ags) to CD8 + T cells by dendritic cells generally requires their entry into the cytosol. Here we show that both…”
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Chikungunya virus-induced autophagy delays caspase-dependent cell death by Joubert, Pierre-Emmanuel, Werneke, Scott W, de la Calle, Claire, Guivel-Benhassine, Florence, Giodini, Alessandra, Peduto, Lucie, Levine, Beth, Schwartz, Olivier, Lenschow, Deborah J, Albert, Matthew L

“…Autophagy is an important survival pathway and can participate in the host response to infection. Studying Chikungunya virus (CHIKV), the causative agent of a…”
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Hsp90-mediated cytosolic refolding of exogenous proteins internalized by dendritic cells by Giodini, Alessandra, Cresswell, Peter

“…Dendritic cells efficiently internalize exogenous protein antigens by fluid‐phase uptake and receptor‐mediated endocytosis. Such antigens contribute to…”
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Receptor-mediated phagocytosis elicits cross-presentation in nonprofessional antigen-presenting cells by Giodini, Alessandra, Rahner, Christoph, Cresswell, Peter

“…In cross-presentation by dendritic cells (DCs), internalized proteins are retrotranslocated into the cytosol, degraded by the proteasome, and the generated…”
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Mechanisms of MHC class I-restricted antigen processing and cross-presentation by Cresswell, Peter, Ackerman, Anne L., Giodini, Alessandra, Peaper, David R., Wearsch, Pamela A.

“…In this review, we discuss recent data from our laboratory that address two aspects of major histocompatibility complex (MHC) class I‐restricted antigen…”
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Enhanced and prolonged cross‐presentation following endosomal escape of exogenous antigens encapsulated in biodegradable nanoparticles by Shen, Hong, Ackerman, Anne L., Cody, Virginia, Giodini, Alessandra, Hinson, Ella R., Cresswell, Peter, Edelson, Richard L., Saltzman, W. Mark, Hanlon, Douglas J.

“…Summary CD8+ T‐cell responses are critical in the immunological control of tumours and infectious diseases. To prime CD8+ T cells against these cell‐associated…”
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Chikungunya-induced cell death is limited by ER and oxidative stress-induced autophagy by Joubert, Pierre-Emmanuel, Werneke, Scott, de la Calle, Claire, Guivel-Benhassine, Florence, Giodini, Alessandra, Peduto, Lucie, Levine, Beth, Schwartz, Olivier, Lenschow, Deborah, Albert, Matthew L.

“…It has been recognized that macroautophagy constitutes an important survival mechanism that allows both the maintenance of cellular homeostasis and the…”
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Survivin exists in immunochemically distinct subcellular pools and is involved in spindle microtubule function by Fortugno, Paola, Wall, Nathan R, Giodini, Alessandra, O'Connor, Daniel S, Plescia, Janet, Padgett, Karen M, Tognin, Simona, Marchisio, Pier Carlo, Altieri, Dario C

“…Survivin is a member of the inhibitor of apoptosis gene family that has been implicated in both apoptosis inhibition and regulation of mitosis. However, the…”
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A whodunit: an appointment with death by Giodini, Alessandra, Albert, Matthew L

“…This is the tale of murder, suicide, evolution, and resurrection, taking place in four parts, and all in the name of antigen cross-priming. We invite you to…”
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Regulation of microtubule stability and mitotic progression by survivin by GIODINI, Alessandra, KALLIO, Marko J, WALL, Nathan R, GORBSKY, Gary J, TOGNIN, Simona, MARCHISIO, Pier Carlo, SYMONS, Marc, ALTIERI, Dario C

“…Survivin is a member of the inhibitor of apoptosis (IAP) gene family, which has been implicated in both preservation of cell viability and regulation of…”
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Chikungunya virus–induced autophagy delays caspase-dependent cell death by Joubert, Pierre-Emmanuel, Werneke, Scott, de la Calle, Claire, Guivel-Benhassine, Florence, Giodini, Alessandra, Peduto, Lucie, Levine, Beth, Schwartz, Olivier, Lenschow, Deborah, Albert, Matthew L.

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The role of endoplasmic reticulum-associated degradation during cross -presentation by dendritic cells by Giodini, Alessandra

“…Dendritic cells (DCs) have the capacity to present endocytosed exogenous antigens on MHC class I molecules: this process is called cross-presentation. For…”
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Mechanisms of MHC class I-restricted antigen processing and cross-presentation: Antigen Processing & Presentation by CRESSWELL, Peter, ACKERMAN, Anne L, GIODINI, Alessandra, PEAPER, David R, WEARSCH, Pamela A

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The human ITGB4BP gene is constitutively expressed in vitro, but highly modulated in vivo by Donadini, A, Giodini, A, Sanvito, F, Marchisio, P C, Biffo, S

“…The ITGB4BP gene encodes for a highly conserved protein, named p27BBP (also known as eIF6), originally identified in mammals as a cytoplasmic interactor of…”
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