Search Results - "Giobbe, Giovanni Giuseppe"
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SARS-CoV-2 infection and replication in human gastric organoids
Published in Nature communications (16-11-2021)“…COVID-19 typically manifests as a respiratory illness, but several clinical reports have described gastrointestinal symptoms. This is particularly true in…”
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2
Extracellular matrix hydrogel derived from decellularized tissues enables endodermal organoid culture
Published in Nature communications (11-12-2019)“…Organoids have extensive therapeutic potential and are increasingly opening up new avenues within regenerative medicine. However, their clinical application is…”
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3
In vitro metabolic zonation through oxygen gradient on a chip
Published in Scientific reports (19-09-2019)“…Among the multiple metabolic signals involved in the establishment of the hepatic zonation, oxygen could play a key role. Indeed, depending on hepatocyte…”
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Hydrogel-in-hydrogel live bioprinting for guidance and control of organoids and organotypic cultures
Published in Nature communications (30-05-2023)“…Three-dimensional hydrogel-based organ-like cultures can be applied to study development, regeneration, and disease in vitro. However, the control of…”
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Paediatric gastric organoids as a tool for disease modelling and clinical translation
Published in Pediatric surgery international (01-03-2021)“…Purpose Knowledge of gastric epithelial homeostasis remains incomplete, lacking human-specific models for study. This study establishes a protocol for deriving…”
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Primary human organoids models: Current progress and key milestones
Published in Frontiers in bioengineering and biotechnology (03-03-2023)“…During the past 10 years the world has experienced enormous progress in the organoids field. Human organoids have shown huge potential to study organ…”
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Human gastro-intestinal organoid engineering: a state of the art
Published in Frontiers in chemical engineering (16-10-2023)“…Gastrointestinal organ failure, from congenital or postnatally acquired pathologies, is a major cause of death across countries of all income levels. Organoids…”
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Intussusception and COVID-19 in Infants: Evidence for an Etiopathologic Correlation
Published in Pediatrics (Evanston) (01-06-2022)“…Nonrespiratory conditions related to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections have been largely described. Ileocolic…”
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Nonwoven fiber meshes for oxygen sensing
Published in Biosensors & bioelectronics (01-07-2024)“…Accurate oxygen sensing and cost-effective fabrication are crucial for the adoption of wearable devices inside and outside the clinical setting. Here we…”
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Generation of human gastric assembloids from primary fetal organoids
Published in Pediatric surgery international (24-11-2023)“…Purpose Understanding human gastric epithelium homeostasis remains partial, motivating the exploration of innovative in vitro models. Recent literature…”
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Stomach engineering: region-specific characterization of the decellularized porcine stomach
Published in Pediatric surgery international (30-11-2023)“…Purpose Patients affected by microgastria, severe gastroesophageal reflux, or those who have undergone subtotal gastrectomy, have commonly described…”
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Single-cell guided prenatal derivation of primary fetal epithelial organoids from human amniotic and tracheal fluids
Published in Nature medicine (01-03-2024)“…Isolation of tissue-specific fetal stem cells and derivation of primary organoids is limited to samples obtained from termination of pregnancies, hampering…”
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Lung viral infection modelling in a bioengineered whole-organ
Published in Biomaterials (01-10-2023)“…Lung infections are one of the leading causes of death worldwide, and this situation has been exacerbated by the emergence of COVID-19. Pre-clinical modelling…”
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