Search Results - "Ginwala, Rashida"
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Potential Role of Flavonoids in Treating Chronic Inflammatory Diseases with a Special Focus on the Anti-Inflammatory Activity of Apigenin
Published in Antioxidants (05-02-2019)“…Inflammation has been reported to be intimately linked to the development or worsening of several non-infectious diseases. A number of chronic conditions such…”
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Apigenin Modulates Dendritic Cell Activities and Curbs Inflammation Via RelB Inhibition in the Context of Neuroinflammatory Diseases
Published in Journal of neuroimmune pharmacology (01-06-2021)“…Neuroinflammation leads to tissue injury causing many of the clinical symptoms of Multiple Sclerosis, an autoimmune disorder of the central nervous system…”
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Regulation of human T-cell leukemia virus type 1 antisense promoter by myocyte enhancer factor-2C in the context of adult T-cell leukemia and lymphoma
Published in Haematologica (Roma) (01-12-2022)“…Adult T-cell leukemia and lymphoma (ATLL) is an intractable T-cell neoplasia caused by a retrovirus, namely human T-cell leukemia virus type 1 (HTLV-1)…”
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Antibody blockade of CLEC12A delays EAE onset and attenuates disease severity by impairing myeloid cell CNS infiltration and restoring positive immunity
Published in Scientific reports (02-06-2017)“…The mechanism of dendritic cells (DCs) recruitment across the blood brain barrier (BBB) during neuroinflammation has been the least explored amongst all…”
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Human Gut Mycobiome and Fungal Community Interaction: The Unknown Musketeer in the Chemotherapy Response Status in Bladder Cancer
Published in European urology open science (Online) (01-09-2022)“…We detected significant differences among the types of fungi present between healthy individuals and bladder cancer patients. Our study was able to…”
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Abstract 2912: Changes in mouse bladder cancer microbiome associated with exposure to bladder carcinogen N-butyl-N-(4-hydroxybutyl) nitrosamine
Published in Cancer research (Chicago, Ill.) (01-07-2021)“…Background: BBN (N-butyl-N-(4-hydroxybuytl) nitrosamine) is the most commonly employed carcinogen in the classical animal model of bladder cancer based on…”
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Nutraceutical Apigenin regulates DC function in a RelB-dependent manner during neuroinflammation
Published in The Journal of immunology (1950) (01-05-2022)“…Apigenin, a natural flavonoid, found in several plants is known to have anti-oxidant and anti-inflammatory properties indicated by its use for centuries as a…”
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Abstract 6096: Bladder cancer microbiome and its association with chemoresponse
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Background: The microbiome is widely known to cause cancer, modify its behavior, and alter the way therapies interact with tumors. Despite the urinary…”
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Myocyte enhancer factor-2C is critical for the maintenance of ATLL cells by regulating the activity of retroviral antisense promoter and bZIP
Published in The Journal of immunology (1950) (01-05-2023)“…Adult T-cell leukemia and lymphoma (ATLL) is an intractable T-cell neoplasia caused by a retrovirus, namely human T-cell leukemia virus type 1 (HTLV-1)…”
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Apigenin, a Natural Flavonoid, Attenuates EAE Severity Through the Modulation of Dendritic Cell and Other Immune Cell Functions
Published in Journal of neuroimmune pharmacology (01-03-2016)“…Apigenin, a natural flavonoid, found in several plants, fruits, vegetables, herbs, and spices, is known to have anti-oxidant and anti-inflammatory properties…”
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Abstract 3060: Changes in mouse gut microbiome upon exposure to N-butyl-N-(4-hydroxybutyl) nitrosamine
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Background: BBN (N-butyl-N-(4-hydroxybuytl) nitrosamine), a closely related compound to the carcinogens found in tobacco smoke is an attractive and most…”
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Abstract 4141: Effects of exercise on tumorigenesis, immune system, and the gut microbiome in a bladder carcinogen mouse model
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Recent studies have begun to demonstrate the therapeutic capacity of physical exercise on cancer treatment outcomes. While this research suggests exercise may…”
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In vivo and in vitro immunogenicity of novel MHC class I presented epitopes to confer protective immunity against chronic HTLV-1 infection
Published in Vaccine (09-08-2018)“…•HTLV-1 is a potentially seriously disabling virus for which there is currently no cure or vaccine.•Immunoproteomics can identify naturally presented epitopes…”
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Regulation and perturbation of Myocyte enhancer factor-2 (MEF-2) activity in Adult T-cell leukemia/lymphoma
Published in The Journal of immunology (1950) (01-05-2019)“…HTLV-1 is a complex human retrovirus, an etiologic agent in causing malignant and intractable T-cell neoplasia. About 5% of the infected population would…”
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Abstract 6624: Immune correlates of response to neoadjuvant chemotherapy in muscle-invasive bladder cancer
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Background: Neoadjuvant chemotherapy followed by radical cystectomy is the optimal treatment for patients with muscle invasive bladder cancer. Between 30 and…”
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Nutraceutical Apigenin: mechanism of action associated with its anti-inflammatory activity and regulation of dendritic cell metabolism
Published in The Journal of immunology (1950) (01-05-2017)“…Flavonoids have a range of biological activities, including anti-inflammatory, anti-carcinogenic, and neuroprotective effects. Apigenin, one such flavonoid…”
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Potential of the Flavonoid Apigenin in Regulating Immune Cell Functions During Neuroinflammation in a RelB-dependent Manner
Published 01-01-2018“…Apigenin, a well-documented health promoting agent, belongs to a group of low-molecular weight phyto-pigments called flavonoids that are present ubiquitously…”
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Dissertation -
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Global Meta-analysis of Urine Microbiome: Colonization of Polycyclic Aromatic Hydrocarbon–degrading Bacteria Among Bladder Cancer Patients
Published in European urology oncology (01-04-2023)“…Our study evaluated the currently available data on urinary microbiome across the globe in addition to our own data, to identify common microbiome signatures,…”
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Abstract 3057: Characterization and functional analysis of microbiome in bladder cancer
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Background: The role of microbiome in genitourinary cancer is an emerging field, with evidence implicating the important role of microbiome as causative…”
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