Search Results - "Ginsburg, S."
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Personalized Medicine: Progress and Promise
Published in Annual review of genomics and human genetics (01-01-2011)“…Personalized medicine is a broad and rapidly advancing field of health care that is informed by each person's unique clinical, genetic, genomic, and…”
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Genomic and personalized medicine: foundations and applications
Published in Translational research : the journal of laboratory and clinical medicine (01-12-2009)“…The last decade has witnessed a steady embrace of genomic and personalized medicine by senior government officials, industry leadership, health care providers,…”
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Genomic medicine: a decade of successes, challenges, and opportunities
Published in Science translational medicine (12-06-2013)“…Genomic medicine--an aspirational term 10 years ago--is gaining momentum across the entire clinical continuum from risk assessment in healthy individuals to…”
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Infertility, infertility treatment, and achievement of pregnancy in female survivors of childhood cancer: a report from the Childhood Cancer Survivor Study cohort
Published in The lancet oncology (01-08-2013)“…Summary Background Previous studies have shown decreased pregnancy rates and early menopause in female cancer survivors; however, infertility rates and…”
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Primary care physicians' knowledge of and experience with pharmacogenetic testing
Published in Clinical genetics (01-10-2012)“…Section Editor: Aad Tibben, email: a.tibben@lumc.nl It is anticipated that as the range of drugs for which pharmacogenetic testing becomes available expands,…”
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Preventing Onset of Anxiety Disorders in Offspring of Anxious Parents: A Randomized Controlled Trial of a Family-Based Intervention
Published in The American journal of psychiatry (01-12-2015)“…Objective:The authors examined the efficacy of a family-based intervention to prevent the onset of anxiety disorders in offspring of anxious…”
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The oral microbiome in health and disease and the potential impact on personalized dental medicine
Published in Oral diseases (01-03-2012)“…Oral Diseases (2012) 18, 109–120 Every human body contains a personalized microbiome that is essential to maintaining health but capable of eliciting disease…”
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Estimated global incidence of Japanese encephalitis: a systematic review
Published in Bulletin of the World Health Organization (01-10-2011)“…To update the estimated global incidence of Japanese encephalitis (JE) using recent data for the purpose of guiding prevention and control efforts. Thirty-two…”
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Dysregulated transcriptional responses to SARS-CoV-2 in the periphery
Published in Nature communications (17-02-2021)“…SARS-CoV-2 infection has been shown to trigger a wide spectrum of immune responses and clinical manifestations in human hosts. Here, we sought to elucidate…”
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Cognitive Behavioral Therapy, Sertraline, or a Combination in Childhood Anxiety
Published in The New England journal of medicine (25-12-2008)“…In this randomized study, children and adolescents with primary diagnoses of separation anxiety or generalized anxiety disorders or social phobia received…”
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Temporal dynamics of host molecular responses differentiate symptomatic and asymptomatic influenza a infection
Published in PLoS genetics (01-08-2011)“…Exposure to influenza viruses is necessary, but not sufficient, for healthy human hosts to develop symptomatic illness. The host response is an important…”
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Measuring Local Gradients of Intramitochondrial [Ca2+] in Cardiac Myocytes During Sarcoplasmic Reticulum Ca2+ Release
Published in Circulation research (01-02-2013)“…RATIONALE:Mitochondrial [Ca] ([Ca]mito) regulates mitochondrial energy production, provides transient Ca buffering under stress, and can be involved in cell…”
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Physician attitudes about non-medical switching to biosimilars: results from an online physician survey in the United States
Published in Current medical research and opinion (03-04-2019)“…Objective: This study was designed to understand the level of familiarity of US rheumatologists, gastroenterologists and dermatologists with biosimilar…”
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The SLCO1B15 Genetic Variant Is Associated With Statin-Induced Side Effects
Published in Journal of the American College of Cardiology (20-10-2009)“…Objectives We sought to identify single nucleotide polymorphisms associated with mild statin-induced side effects. Background Statin-induced side effects can…”
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Predictors and Moderators of Treatment Response in Childhood Anxiety Disorders: Results From the CAMS Trial
Published in Journal of consulting and clinical psychology (01-04-2014)“…Objective: We sought to examine predictors and moderators of treatment outcomes among 488 youths ages 7-17 years (50% female; 74% ≤ 12 years) meeting…”
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Deep Sequencing of Influenza A Virus from a Human Challenge Study Reveals a Selective Bottleneck and Only Limited Intrahost Genetic Diversification
Published in Journal of virology (15-12-2016)“…Knowledge of influenza virus evolution at the point of transmission and at the intrahost level remains limited, particularly for human hosts. Here, we analyze…”
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Patient attitudes about non-medical switching to biosimilars: results from an online patient survey in the United States
Published in Current medical research and opinion (03-04-2019)“…Objective: To evaluate patient attitudes regarding non-medical switching (NMS) to biosimilars among patients with autoimmune disease currently receiving a…”
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Aligning incentives to fulfil the promise of personalised medicine
Published in The Lancet (British edition) (23-05-2015)“…The full promise of personalised and precision medicine (PPM)--as health-care innovations involving molecular diagnostics and pharmacogenomics are…”
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Complex electrophysiological remodeling in postinfarction ischemic heart failure
Published in Proceedings of the National Academy of Sciences - PNAS (27-03-2018)“…Heart failure (HF) following myocardial infarction (MI) is associated with high incidence of cardiac arrhythmias. Development of therapeutic strategy requires…”
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H3N2 influenza infection elicits more cross-reactive and less clonally expanded anti-hemagglutinin antibodies than influenza vaccination
Published in PloS one (19-10-2011)“…During the recent H1N1 influenza pandemic, excess morbidity and mortality was seen in young but not older adults suggesting that prior infection with influenza…”
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