Search Results - "Gingrich, Jeremy"

Sex-Specific Modulation of Fetal Adipogenesis by Gestational Bisphenol A and Bisphenol S Exposure by Pu, Yong, Gingrich, Jeremy D, Steibel, Juan P, Veiga-Lopez, Almudena

“…The endocrine-disrupting chemical bisphenol A (BPA) increases adipose tissue mass in vivo and promotes adipogenesis in vitro; however, mechanisms explaining…”
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Pregnancy-specific physiologically-based toxicokinetic models for bisphenol A and bisphenol S by Gingrich, Jeremy, Filipovic, David, Conolly, Rory, Bhattacharya, Sudin, Veiga-Lopez, Almudena

“…[Display omitted] •Two open-source pregnancy PBTK models for BPS and BPA were successfully developed.•A 2-week daily maternal exposure simulation with the EPA…”
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Bisphenol S Impairs Invasion and Proliferation of Extravillous Trophoblasts Cells by Interfering with Epidermal Growth Factor Receptor Signaling by Ticiani, Elvis, Pu, Yong, Gingrich, Jeremy, Veiga-Lopez, Almudena

“…The placenta supports fetal growth and is vulnerable to exogenous chemical exposures. We have previously demonstrated that exposure to the emerging chemical…”
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Exclusion of the unfolded protein response in light-induced retinal degeneration in the canine T4R RHO model of autosomal dominant retinitis pigmentosa by Marsili, Stefania, Genini, Sem, Sudharsan, Raghavi, Gingrich, Jeremy, Aguirre, Gustavo D, Beltran, William A

“…To examine the occurrence of endoplasmic reticulum (ER) stress and the unfolded protein response (UPR) following acute light damage in the naturally-occurring…”
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Placenta Disrupted: Endocrine Disrupting Chemicals and Pregnancy by Gingrich, Jeremy, Ticiani, Elvis, Veiga-Lopez, Almudena

“…Endocrine disrupting chemicals (EDCs) are chemicals that can interfere with normal endocrine signals. Human exposure to EDCs is particularly concerning during…”
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A 3-dimensional microfluidic platform for modeling human extravillous trophoblast invasion and toxicological screening by Pu, Yong, Gingrich, Jeremy, Veiga-Lopez, Almudena

“…Placental trophoblast cells invasion into the maternal uterus is an essential and complex event in the formation of the maternal-fetal interface. Commonly used…”
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Obesogenic Endocrine Disrupting Chemicals: Identifying Knowledge Gaps by Veiga-Lopez, Almudena, Pu, Yong, Gingrich, Jeremy, Padmanabhan, Vasantha

“…Endocrine disrupting chemicals (EDCs) are compounds that are part of everyday consumer products and industrial manufacturing processes. EDCs can interfere with…”
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Toxicokinetics of bisphenol A, bisphenol S, and bisphenol F in a pregnancy sheep model by Gingrich, Jeremy, Pu, Yong, Ehrhardt, Richard, Karthikraj, Rajendiran, Kannan, Kurunthachalam, Veiga-Lopez, Almudena

“…Bisphenol A (BPA), S (BPS), and F (BPF) are among the most abundant bisphenols detected in humans, yet pregnancy toxicokinetics for BPS or BPF remain unknown…”
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Review of the oral toxicity of cannabidiol (CBD) by Gingrich, Jeremy, Choudhuri, Supratim, Cournoyer, Patrick, Downey, Jason, Muldoon Jacobs, Kristi

“…Information in the published literature indicates that consumption of CBD can result in developmental and reproductive toxicity and hepatotoxicity outcomes in…”
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Gestational Exposure to Bisphenol A and Bisphenol S Leads to Fetal Skeletal Muscle Hypertrophy Independent of Sex by Jing, Jiongjie, Pu, Yong, Gingrich, Jeremy, Veiga-Lopez, Almudena

“…Abstract Gestational exposure to bisphenol A (BPA) can lead to offspring insulin resistance. However, despite the role that the skeletal muscle plays in…”
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Gestational bisphenol S impairs placental endocrine function and the fusogenic trophoblast signaling pathway by Gingrich, Jeremy, Pu, Yong, Roberts, Jennifer, Karthikraj, Rajendiran, Kannan, Kurunthachalam, Ehrhardt, Richard, Veiga-Lopez, Almudena

“…Exposure to bisphenolic chemicals during pregnancy occurs in > 90% of pregnancies. Bisphenolic compounds can cross the placental barrier reaching fetal…”
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A modified parachute assay for assessment of gap junction intercellular communication in placental trophoblast cells by Gingrich, Jeremy, Pu, Yong, Veiga-Lopez, Almudena

“…Gap junction intercellular communication (GJIC) is a necessary process for placental development. GJIC can be assessed with a parachute assay, where…”
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Investigation of cannabidiol-induced cytotoxicity in human hepatic cells by Chen, Si, Li, Xilin, Wu, Qiangen, Li, Yuxi, Puig, Montserrat, Moulin, Frederic, Choudhuri, Supratim, Gingrich, Jeremy, Guo, Lei

“…Cannabidiol (CBD) is one of the primary cannabinoids present in extracts of the plant Cannabis sativa L. A CBD-based drug, Epidiolex, has been approved by the…”
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Bisphenol S and Epidermal Growth Factor Receptor Signaling in Human Placental Cytotrophoblasts by Ticiani, Elvis, Gingrich, Jeremy, Pu, Yong, Vettathu, Mathew, Davis, Jacquelyn, Martin, Denny, Petroff, Margaret G, Veiga-Lopez, Almudena

“…Bisphenol S (BPS) is an endocrine-disrupting chemical and the second most abundant bisphenol detected in humans. BPS exposure leads to reduced binucleate cell…”
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Bisphenol S enhances gap junction intercellular communication in ovarian theca cells by Gingrich, Jeremy, Pu, Yong, Upham, Brad L., Hulse, Madeline, Pearl, Sarah, Martin, Denny, Avery, Anita, Veiga-Lopez, Almudena

“…Gap junction intercellular communication (GJIC) is necessary for ovarian function, and it is temporospatially regulated during follicular development and…”
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Response to the letter to the editor by Gingrich, Jeremy, Pu, Yong, Ehrhardt, Richard, Karthikraj, Rajendiran, Kannan, Kurunthachalam, Veiga-Lopez, Almudena

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The Effects of Endocrine Disrupting Chemicals on Placental Development and Function by Gingrich, Jeremy

“…Endocrine disrupting chemicals (EDCs) are compounds that can interfere with normal endocrine functions. Human exposure to EDCs is particularly concerning…”
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Multispecies study: low-dose tributyltin impairs ovarian theca cell cholesterol homeostasis through the RXR pathway in five mammalian species including humans by Pu, Yong, Pearl, Sarah, Gingrich, Jeremy, Jing, Jiongjie, Martin, Denny, Murga-Zamalloa, Carlos A., Veiga-Lopez, Almudena

“…Tributyltin (TBT), an organotin chemical used as a catalyst and biocide, can stimulate cholesterol efflux in non-steroidogenic cells. Since cholesterol is the…”
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Expression of ABC transporters during syncytialization in preeclampsia by Sethuraman, Visalakshi, Pu, Yong, Gingrich, Jeremy, Jing, Jiongjie, Long, Robert, Olomu, Isoken Nicholas, Veiga-Lopez, Almudena

“…•Placental expression of ABC transporters is unaltered in preeclampsia.•ABC transporters have a dynamic expression during trophoblast syncytialization.•ABC…”
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