Search Results - "Gingrich, David"

Development and validation of an LC-MS/MS method for determination of hydroxychloroquine, its two metabolites, and azithromycin in EDTA-treated human plasma by Sok, Vong, Marzan, Florence, Gingrich, David, Aweeka, Francesca, Huang, Liusheng

“…Hydroxychloroquine (HCQ) and azithromycin (AZM) are antimalarial drugs recently reported to be active against severe acute respiratory syndrome coronavirus- 2…”
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Exposure to pesticides in utero impacts the fetal immune system and response to vaccination in infancy by Prahl, Mary, Odorizzi, Pamela, Gingrich, David, Muhindo, Mary, McIntyre, Tara, Budker, Rachel, Jagannathan, Prasanna, Farrington, Lila, Nalubega, Mayimuna, Nankya, Felistas, Sikyomu, Esther, Musinguzi, Kenneth, Naluwu, Kate, Auma, Ann, Kakuru, Abel, Kamya, Moses R., Dorsey, Grant, Aweeka, Francesca, Feeney, Margaret E.

“…The use of pesticides to reduce mosquito vector populations is a cornerstone of global malaria control efforts, but the biological impact of most pesticides on…”
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High-parameter phenotypic characterization reveals a subset of human Th17 cells that preferentially produce IL-17 against M. tuberculosis antigen by Ogongo, Paul, Tran, Anthony, Marzan, Florence, Gingrich, David, Krone, Melissa, Aweeka, Francesca, Lindestam Arlehamn, Cecilia S, Martin, Jeffrey N, Deeks, Steven G, Hunt, Peter W, Ernst, Joel D

“…Interleukin-17-producing CD4 T cells contribute to the control of ( ) infection in humans; whether infection with human immunodeficiency virus (HIV)…”
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Distinct genes related to drug response identified in ER positive and ER negative breast cancer cell lines by Shen, Kui, Rice, Shara D, Gingrich, David A, Wang, Dakun, Mi, Zhibao, Tian, Chunqiao, Ding, Zhenyu, Brower, Stacey L, Ervin, Jr, Paul R, Gabrin, Michael J, Tseng, George, Song, Nan

“…Breast cancer patients have different responses to chemotherapeutic treatments. Genes associated with drug response can provide insight to understand the…”
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Female Genital Fibroblasts Diminish the In Vitro Efficacy of PrEP against HIV by George, Ashley F, McGregor, Matthew, Gingrich, David, Neidleman, Jason, Marquez, Rebecca S, Young, Kyrlia C, Thanigaivelan, Kaavya L, Greene, Warner C, Tien, Phyllis C, Deitchman, Amelia N, Spitzer, Trimble L, Roan, Nadia R

“…The efficacy of HIV pre-exposure prophylaxis (PrEP) is high in men who have sex with men, but much more variable in women, in a manner largely attributed to…”
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Quantification of N, N’ N’’-triethylenethiophosphoramide, N, N’ N’’-triethylenephosphoramide, cyclophosphamide, and 4-hydroxy-cyclophosphamide in microvolume human plasma to support neonatal and pediatric drug studies by Huang, Liusheng, Winger, Beth Apsel, Cheah, Vincent, Gingrich, David, Marzan, Florence, Lu, Ying, Cooper, Jennifer C., Aweeka, Francesca, Long-Boyle, Janel

“…•Two LC-MS/MS assays were developed based on the same analytical platform.•A Poroshell PFP column was used enabling a high flow rate and shorter run time (4.5…”
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Concomitant nevirapine impacts pharmacokinetic exposure to the antimalarial artemether-lumefantrine in African children by Huang, Liusheng, Carey, Vincent, Lindsey, Jane C, Marzan, Florence, Gingrich, David, Graham, Bobbie, Barlow-Mosha, Linda, Ssemambo, Phionah K, Kamthunzi, Portia, Nachman, Sharon, Parikh, Sunil, Aweeka, Francesca T

“…The antiretroviral drug nevirapine and the antimalarial artemisinin-based combination therapy artemether-lumefantrine are commonly co-administered to treat…”
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Rapid Variable-Number Tandem-Repeat Genotyping for Mycobacterium leprae Clinical Specimens by Kimura, Miyako, Sakamuri, Rama Murthy, Groathouse, Nathan A, Rivoire, Becky L, Gingrich, David, Krueger-Koplin, Susan, Cho, Sang-Nae, Brennan, Patrick J, Vissa, Varalakshmi

“…Mycobacterium leprae is the noncultivable pathogen of leprosy. Since the genome sequence of an isolate of M. leprae has become available, multiple-locus…”
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Drug-Drug Interaction Between Dihydroartemisinin-Piperaquine and Sulfadoxine-Pyrimethamine During Malaria Chemoprevention in Pregnant Women by Mwebaza, Norah, Roh, Michelle E, Geng, Yourong Z, Opio, Leonard, Opira, Bishop, Marzan, Florence, Mwima, Moses W, Ssemukuye, Timothy, Guo, Kevin, Gingrich, David, Fotaki, Nikoletta, Kakuru, Abel, Kizza, Jimmy, Aguti, Miriam, Adrama, Harriet, Kamya, Moses, Dorsey, Grant, Rosenthal, Philip J, Aweeka, Francesca T, Huang, Liusheng

“…Co-administration of dihydroartemisinin-piperaquine (DP) and sulfadoxine-pyrimethamine (SP) for intermittent preventive treatment of malaria in pregnancy…”
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Abstract PS8-13: Silicone implant based sustained localized drug delivery of fulvestrant to prevent breast cancer by Munster, Pamela N, Desai, Pujan K, Pawlowska, Nela, Roche, Elysia, Pacaud, Romain, Daud, Maxim A, Hsu, Emily, Gingrich, David, Deitchman, Amelia, Aweeka, Fran, Thomas, Scott

“…Abstract Background: Hereditary breast cancer is common. With enhanced awareness and the recent introduction in affordable multi-gene germ line testing, an…”
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Pharmacogenetic interactions between antiretroviral drugs and vaginally administered hormonal contraceptives by Haas, David W., Cramer, Yoninah S., Godfrey, Catherine, Rosenkranz, Susan L., Aweeka, Francesca, Berzins, Baiba, Coombs, Robert, Coughlin, Kristine, Moran, Laura E., Gingrich, David, Zorrilla, Carmen D., Baker, Paxton, Cohn, Susan E., Scarsi, Kimberly K.

“…OBJECTIVEIn AIDS Clinical Trials Group study A5316, efavirenz lowered plasma concentrations of etonogestrel and ethinyl estradiol, given as a vaginal ring,…”
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Cloning a Histidine‐rich Loop of the CrMTP1 Protein of Chlamydomonas reinhardtii by Yang, Huidong, Gingrich, David J

“…Zinc plays several roles in cellular metabolism. To accomplish this, the amount and forms of zinc must be controled within the cell. One important aspect of…”
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Methotrexate Decreases Tenofovir Exposure in Antiretroviral-Suppressed Individuals Living With HIV by Gingrich, David, Deitchman, Amelia N., Kantor, Amy, Huang, Liusheng, Stein, James H., Currier, Judith S., Hsue, Priscilla Y., Ribaudo, Heather J., Aweeka, Francesca T.

“…To mitigate increased risk of premature cardiovascular disease in antiretroviral therapy (ART) suppressed adults living with HIV (PWH), low-dose methotrexate…”
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Quantification of N, N' N"-triethylenethiophosphoramide, N, N"-triethylenephosphoramide, cyclophosphamide, and 4-hydroxy-cyclophosphamide in microvolume human plasma to support neonatal and pediatric drug studies by Huang, Liusheng, Winger, Beth Apsel, Cheah, Vincent, Gingrich, David, Marzan, Florence, Lu, Ying, Cooper, Jennifer C, Aweeka, Francesca, Long-Boyle, Janel

“…N, N’ N”-triethylenethiophosphoramide (thiotepa) and cyclophosphamide (CP) are alkylating agents used for a variety of malignant and non-malignant disorders…”
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Determination of artemether and dihydroartemisinin in human plasma with a new hydrogen peroxide stabilization method by Huang, Liusheng, Olson, Alexander, Gingrich, David, Aweeka, Francesca T

“…Numerous methods have been reported for the determination of artemether (ARM) and its metabolite dihydroartemisinin (DHA) in plasma. However, stability issues…”
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The effect of malnutrition on the pharmacokinetics and virologic outcomes of lopinavir, efavirenz and nevirapine in food insecure HIV-infected children in Tororo, Uganda by Bartelink, Imke H, Savic, Rada M, Dorsey, Grant, Ruel, Theodore, Gingrich, David, Scherpbier, Henriette J, Capparelli, Edmund, Jullien, Vincent, Young, Sera L, Achan, Jane, Plenty, Albert, Charlebois, Edwin, Kamya, Moses, Havlir, Diane, Aweeka, Francesca

“…Malnutrition may impact the pharmacokinetics (PKs) of antiretroviral medications and virologic responses in HIV-infected children. The authors therefore…”
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Antiretroviral therapy and vaginally administered contraceptive hormones: a three-arm, pharmacokinetic study by Scarsi, Kimberly K, Cramer, Yoninah S, Rosenkranz, Susan L, Aweeka, Francesca, Berzins, Baiba, Coombs, Robert W, Coughlin, Kristine, Moran, Laura E, Zorrilla, Carmen D, Akelo, Victor, Aziz, Mariam, Friedman, Ruth K, Gingrich, David, Swaminathan, Shobha, Godfrey, Catherine, Cohn, Susan E, Barr, Liz, Blanchard-Horan, Christina, Connick, Elizabeth, Cermak, Mary Allegra, Chakhtoura, Nahida, Chang-Ching, Cecelia, Fox, Andee, Haas, David W., Landay, Alan, Leon, Mey, Park, Jeong-Gun, Patterson, Kristine, Sise, Thucuma, Spear, Greg, Shugarts, David, Tshandu, Pamela, Wira, Charles R

“…Drug-drug interactions between orally administered antiretroviral therapy (ART) and hormones released from an intravaginal ring are not known. We hypothesised…”
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Interactions between antiretroviral therapy and vaginally administered contraceptive hormones: A three–arm, pharmacokinetic evaluation by Scarsi, Kimberly K., Cramer, Yoninah S., Rosenkranz, Susan L., Aweeka, Francesca, Berzins, Baiba, Coombs, Robert W., Coughlin, Kristine, Moran, Laura E., Zorrilla, Carmen D., Akelo, Victor, Aziz, Mariam, Friedman, Ruth K., Gingrich, David, Swaminathan, Shobha, Godfrey, Catherine, Cohn, Susan E.

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Porphyrin vinyl groups act as antennae for electron transfer within [iron,zinc] hemoglobin hybrids by Gingrich, David J, Nocek, Judith M, Natan, Michael J, Hoffman, Brian M

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Cloning a Putative Zinc Transport Protein from Chalamydomonas reinhardtii by McBride, Fancy T, Gingrich, David J

“…Cells must regulate the cellular concentrations of metal ions. One aspect of this control involves the use of metal ion transport proteins in membranes and…”
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