Search Results - "Ginger, Melanie"

Endogenous noise of neocortical neurons correlates with atypical sensory response variability in the Fmr1−/y mouse model of autism by Bhaskaran, Arjun A., Gauvrit, Théo, Vyas, Yukti, Bony, Guillaume, Ginger, Melanie, Frick, Andreas

“…Excessive neural variability of sensory responses is a hallmark of atypical sensory processing in autistic individuals with cascading effects on other core…”
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Dendritic channelopathies contribute to neocortical and sensory hyperexcitability in Fmr1−/y mice by Zhang, Yu, Bonnan, Audrey, Bony, Guillaume, Ferezou, Isabelle, Pietropaolo, Susanna, Ginger, Melanie, Sans, Nathalie, Rossier, Jean, Oostra, Ben, LeMasson, Gwen, Frick, Andreas

“…Fragile X Syndrome (FXS) patients and the mouse model of the disease are known to have increased neocortical network excitability and hypersensitivity to…”
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Altered surface mGluR5 dynamics provoke synaptic NMDAR dysfunction and cognitive defects in Fmr1 knockout mice by Aloisi, Elisabetta, Le Corf, Katy, Dupuis, Julien, Zhang, Pei, Ginger, Melanie, Labrousse, Virginie, Spatuzza, Michela, Georg Haberl, Matthias, Costa, Lara, Shigemoto, Ryuichi, Tappe-Theodor, Anke, Drago, Filippo, Vincenzo Piazza, Pier, Mulle, Christophe, Groc, Laurent, Ciranna, Lucia, Catania, Maria Vincenza, Frick, Andreas

“…Metabotropic glutamate receptor subtype 5 (mGluR5) is crucially implicated in the pathophysiology of Fragile X Syndrome (FXS); however, its dysfunction at the…”
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noncoding RNA is a potential marker of cell fate during mammary gland development by Ginger, M.R, Shore, A.N, Contreras, A, Rijnkels, M, Miller, J, Gonzalez-Rimbau, M.F, Rosen, J.M

“…PINC is a large, alternatively spliced, developmentally regulated, noncoding RNA expressed in the regressed terminal ductal lobular unit-like structures of the…”
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Synaptic ionotropic glutamate receptors and plasticity are developmentally altered in the CA1 field of Fmr1 knockout mice by Pilpel, Yair, Kolleker, Aleksander, Berberich, Sven, Ginger, Melanie, Frick, Andreas, Mientjes, Edwin, Oostra, Ben A., Seeburg, Peter H.

“…Fragile X syndrome is one of the most common forms of mental retardation, yet little is known about the physiological mechanisms causing the disease. In this…”
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An anterograde rabies virus vector for high-resolution large-scale reconstruction of 3D neuron morphology by Haberl, Matthias Georg, Viana da Silva, Silvia, Guest, Jason M., Ginger, Melanie, Ghanem, Alexander, Mulle, Christophe, Oberlaender, Marcel, Conzelmann, Karl-Klaus, Frick, Andreas

“…Glycoprotein-deleted rabies virus (RABV ∆G) is a powerful tool for the analysis of neural circuits. Here, we demonstrate the utility of an anterograde RABV ∆G…”
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Persistent Changes in Gene Expression Induced by Estrogen and Progesterone in the Rat Mammary Gland by Ginger, Melanie R, Gonzalez-Rimbau, Maria F, Gay, Jason P, Rosen, Jeffrey M

“…Epidemiological studies have consistently shown that an early full-term pregnancy is protective against breast cancer. We hypothesize that the hormonal milieu…”
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Pregnancy-induced changes in cell-fate in the mammary gland by Ginger, Melanie R, Rosen, Jeffrey M

“…The protective effect of an early full-term pregnancy is a well established phenomenon; in contrast, the molecular and cell-specific mechanisms that govern…”
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Comparative aspects of milk caseins by Ginger, Melanie R, Grigor, Murray R

“…The caseins comprise the major protein component of milk of most mammals and are secreted as micelles that also carry high concentrations of calcium. They are…”
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Dendritic channelopathies contribute to neocortical and sensory hyperexcitability in Fmr1(-/y) mice by Zhang, Yu, Bonnan, Audrey, Bony, Guillaume, Ferezou, Isabelle, Pietropaolo, Susanna, Ginger, Melanie, Sans, Nathalie, Rossier, Jean, Oostra, Ben, LeMasson, Gwen, Frick, Andreas

“…Hypersensitivity in response to sensory stimuli and neocortical hyperexcitability are prominent features of Fragile X Syndrome (FXS) and autism spectrum…”
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Behavioral abnormalities in the Fmr1‐KO2 mouse model of fragile X syndrome: The relevance of early life phases by Gaudissard, Julie, Ginger, Melanie, Premoli, Marika, Memo, Maurizio, Frick, Andreas, Pietropaolo, Susanna

“…Fragile X syndrome (FXS) is a developmental disorder caused by a mutation in the X‐linked FMR1 gene, coding for the FMRP protein which is largely involved in…”
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Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndrome by Jung, Kwang-Mook, Sepers, Marja, Henstridge, Christopher M., Lassalle, Olivier, Neuhofer, Daniela, Martin, Henry, Ginger, Melanie, Frick, Andreas, DiPatrizio, Nicholas V., Mackie, Ken, Katona, Istvan, Piomelli, Daniele, Manzoni, Olivier J.

“…Fragile X syndrome, the most commonly known genetic cause of autism, is due to loss of the fragile X mental retardation protein, which regulates signal…”
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Potential Involvement of Impaired BK Ca Channel Function in Sensory Defensiveness and Some Behavioral Disturbances Induced by Unfamiliar Environment in a Mouse Model of Fragile X Syndrome by Carreno-Munoz, Maria Isabel, Martins, Fabienne, Medrano, Maria Carmen, Aloisi, Elisabetta, Pietropaolo, Susanna, Dechaud, Corentin, Subashi, Enejda, Bony, Guillaume, Ginger, Melanie, Moujahid, Abdelmalik, Frick, Andreas, Leinekugel, Xavier

“…In fragile X syndrome (FXS), sensory hypersensitivity and impaired habituation is thought to result in attention overload and various behavioral abnormalities…”
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Dual Anterograde and Retrograde Viral Tracing of Reciprocal Connectivity by Haberl, Matthias G, Ginger, Melanie, Frick, Andreas

“…Current large-scale approaches in neuroscience aim to unravel the complete connectivity map of specific neuronal circuits, or even the entire brain. This…”
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Structural-functional connectivity deficits of neocortical circuits in the Fmr1 (-/y) mouse model of autism by Haberl, Matthias G, Zerbi, Valerio, Veltien, Andor, Ginger, Melanie, Heerschap, Arend, Frick, Andreas

“…Fragile X syndrome (FXS), the most common inherited form of intellectual disability disorder and a frequent cause of autism spectrum disorder (ASD), is…”
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Potential Involvement of Impaired BKCa Channel Function in Sensory Defensiveness and Some Behavioral Disturbances Induced by Unfamiliar Environment in a Mouse Model of Fragile X Syndrome by Carreno-Munoz, Maria Isabel, Martins, Fabienne, Medrano, Maria Carmen, Aloisi, Elisabetta, Pietropaolo, Susanna, Dechaud, Corentin, Subashi, Enejda, Bony, Guillaume, Ginger, Melanie, Moujahid, Abdelmalik, Frick, Andreas, Leinekugel, Xavier

“…In fragile X syndrome (FXS), sensory hypersensitivity and impaired habituation is thought to result in attention overload and various behavioral abnormalities…”
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Dendritic channelopathies contribute to neocortical and sensory hyperexcitability in [Fmr1.sup.-/y] mice by Zhang, Yu, Bonnan, Audrey, Bony, Guillaume, Ferezou, Isabelle, Pietropaolo, Susanna, Ginger, Melanie, Sans, Nathalie, Rossier, Jean, Oostra, Ben, LeMasson, Gwen, Frick, Andreas

“…Hypersensitivity in response to sensory stimuli and neocortical hyperexcitability are prominent features of Fragile X Syndrome (FXS) and autism spectrum…”
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Dendritic channelopathies contribute to neocortical and sensory hyperexcitability in Fmr1 super(-/y) mice by Zhang, Yu, Bonnan, Audrey, Bony, Guillaume, Ferezou, Isabelle, Pietropaolo, Susanna, Ginger, Melanie, Sans, Nathalie, Rossier, Jean, Oostra, Ben, LeMasson, Gwen, Frick, Andreas

“…Hypersensitivity in response to sensory stimuli and neocortical hyperexcitability are prominent features of Fragile X Syndrome (FXS) and autism spectrum…”
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Revealing the secrets of neuronal circuits with recombinant rabies virus technology by Ginger, Melanie, Haberl, Matthias, Conzelmann, Karl-Klaus, Schwarz, Martin K, Frick, Andreas

“…An understanding of how the brain processes information requires knowledge of the architecture of its underlying neuronal circuits, as well as insights into…”
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Three-dimensional tracking and analysis of ion channel signals across dendritic arbors by Ginger, Melanie, Broser, Philip, Frick, Andreas

“…Most neuron types possess elaborate dendritic arbors that receive and integrate excitatory and inhibitory inputs from numerous other neurons to give rise to…”
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