Search Results - "Gingele, Stefan"
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CIDP associated with Sjögren’s syndrome
Published in Journal of neurology (01-08-2021)“…Background This study addresses the challenging characterisation and differentiation of CIDP versus CIDP in association with Sjögren’s syndrome to facilitate…”
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Neuro-Sjögren: Peripheral Neuropathy With Limb Weakness in Sjögren's Syndrome
Published in Frontiers in immunology (11-07-2019)“…Sjögren's syndrome is a heterogeneous inflammatory disorder frequently involving peripheral nerves with a wide spectrum of sensory modalities and distribution…”
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Role of CD20+ T cells in multiple sclerosis: implications for treatment with ocrelizumab
Published in Neural regeneration research (01-04-2020)“…Among others, expression of interferon-γ (IFNγ), interleukin (IL)-1β as well as other ILs, IL-2, IL-4, IL-8 and IL-10, chemokine (C-C motif) ligand 2,…”
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Severe allo-immune antibody-associated peripheral and central nervous system diseases after allogeneic hematopoietic stem cell transplantation
Published in Scientific reports (19-04-2021)“…Allogeneic hematopoietic stem cell transplantation (alloHSCT) is a curative treatment for hematologic malignancies. Acute and chronic graft-versus-host disease…”
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The relevance of NMDA receptor antibody-specific index for diagnosis and prognosis in patients with anti-NMDA receptor encephalitis
Published in Scientific reports (04-08-2023)“…The clinical implications of the presence of anti-N-methyl-D-aspartate receptor (NMDAR)-specific intrathecal immunoglobulin G synthesis and whether it…”
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The Persisting Significance of Oligoclonal Bands in the Dawning Era of Kappa Free Light Chains for the Diagnosis of Multiple Sclerosis
Published in International journal of molecular sciences (29-11-2018)“…The latest revision of the McDonald criteria of 2017 considers the evidence of an intrathecal immunoglobulin (IgG) synthesis as a diagnostic criterion for…”
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Impact of the McDonald Criteria 2017 on Early Diagnosis of Relapsing-Remitting Multiple Sclerosis
Published in Frontiers in neurology (15-03-2019)“…Multiple sclerosis is a chronic immune mediated demyelinating disease leading to neurological disabilities that need to be diagnosed and treated early…”
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Clinical and paraclinical characteristics of optic neuritis in the context of the McDonald criteria 2017
Published in Scientific reports (27-03-2024)“…Optic neuritis is often an initial symptom in multiple sclerosis (MS) or clinically isolated syndrome (CIS), yet comprehensive studies using the 2017 McDonald…”
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Regenerative Effects of CDP-Choline: A Dose-Dependent Study in the Toxic Cuprizone Model of De- and Remyelination
Published in Pharmaceuticals (Basel, Switzerland) (12-11-2021)“…Inflammatory attacks and demyelination in the central nervous system (CNS) are the key factors responsible for the damage of neurons in multiple sclerosis…”
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The Effect of Stereotactic Injections on Demyelination and Remyelination: a Study in the Cuprizone Model
Published in Journal of molecular neuroscience (01-04-2017)“…Remyelination is the natural repair mechanism in demyelinating disorders of the central nervous system (CNS) such as multiple sclerosis. Several animal models…”
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Ocrelizumab Depletes CD20⁺ T Cells in Multiple Sclerosis Patients
Published in Cells (Basel, Switzerland) (28-12-2018)“…Ocrelizumab, a humanized monoclonal anti-CD20 antibody, has shown pronounced effects in reduction of disease activity in multiple sclerosis (MS) patients and…”
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Hereditary transthyretin-related amyloidosis is frequent in polyneuropathy and cardiomyopathy of no obvious aetiology
Published in Annals of medicine (Helsinki) (01-01-2021)“…Hereditary Transthyretin-Related Amyloidosis, a clinically heterogeneous autosomal dominant disease caused by pathogenic variants in the TTR gene, is…”
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Comparative analysis of albumin quotient and total CSF protein in immune-mediated neuropathies: a multicenter study on diagnostic implications
Published in Frontiers in neurology (09-01-2024)“…Blood-cerebrospinal fluid (CSF) barrier dysfunction is pivotal for diagnosing immune-mediated neuropathies, especially in spinal nerve root inflammation…”
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Cuprizone effect on myelination, astrogliosis and microglia attraction in the mouse basal ganglia
Published in Brain research (11-12-2009)“…Abstract Multiple sclerosis is the leading cause of neurological disability in young adults affecting more than two million people worldwide. Although multiple…”
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The Increasing Role of Kappa Free Light Chains in the Diagnosis of Multiple Sclerosis
Published in Cells (Basel, Switzerland) (06-11-2021)“…Free light chains (FLC) are a promising biomarker to detect intrathecal inflammation in patients with inflammatory central nervous system (CNS) diseases,…”
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Investigation of Oligoclonal IgG Bands in Tear Fluid of Multiple Sclerosis Patients
Published in Frontiers in immunology (17-05-2019)“…Oligoclonal IgG bands (OCB) in the cerebrospinal fluid (CSF) represent a typical marker for inflammation in multiple sclerosis (MS) patients and have a…”
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Autoantibody-associated psychiatric symptoms and syndromes in adults: A narrative review and proposed diagnostic approach
Published in Brain, behavior, & immunity. Health (01-12-2020)“…Autoimmune-mediated encephalitis is a disease that often encompasses psychiatric symptoms as its first clinical manifestation’s predominant and isolated…”
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Switch from intravenous to subcutaneous immunoglobulin IgPro20 in CIDP patients: a prospective observational study under real-world conditions
Published in Therapeutic advances in neurological disorders (2021)“…Background: IgPro20 is the first approved subcutaneous immunoglobulin (SCIg) preparation for the treatment of patients with chronic inflammatory demyelinating…”
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Delayed Demyelination and Impaired Remyelination in Aged Mice in the Cuprizone Model
Published in Cells (Basel, Switzerland) (11-04-2020)“…To unravel the failure of remyelination in multiple sclerosis (MS) and to test promising remyelinating treatments, suitable animal models like the…”
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Immunophenotyping of cerebrospinal fluid cells by Chipcytometry
Published in Journal of neuroinflammation (25-05-2018)“…The gold standard in cerebrospinal fluid (CSF) cell immunophenotyping is flow cytometry. Nevertheless, the small amount of CSF cells and the invasive character…”
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