Search Results - "Giner, R. M."

Traditional chinese medicine remedy to jury: the pharmacological basis for the use of shikonin as an anticancer therapy by Andújar, I, Recio, M C, Giner, R M, Ríos, J L

“…Shikonin is the major constituent of the root of Lithospermum erythrorhizon, which has been used in traditional Chinese medicine to treat external wounds,…”
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Cucurbitacins as inducers of cell death and a rich source of potential anticancer compounds by Ríos, J L, Andújar, I, Escandell, J M, Giner, R M, Recio, M C

“…Triterpenes have been reported to induce cell death. One relevant group of this family of compounds is cucurbitacins, which have been studied as inducers of…”
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Influence of traditional Chinese anti-inflammatory medicinal plants on leukocyte and platelet functions by Prieto, J. M., Recio, M. C., Giner, R. M., Máñez, S., Giner-Larza, E. M., Ríos, J. L.

“…ABSTRACT The enzymes 5‐lipoxygenase and elastase are therapeutic targets in dermatological disorders such as psoriasis. Fifteen extracts from traditional…”
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Shikonin reduces oedema induced by phorbol ester by interfering with IκBα degradation thus inhibiting translocation of NF‐κB to the nucleus by Andújar, I, Recio, MC, Bacelli, T, Giner, RM, Ríos, JL

“…Background and purpose:  In the present paper we studied the effect of shikonin on ear oedema induced by 12‐O‐tetradecanoylphorbol‐13‐acetate (TPA), and…”
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update review of saffron and its active constituents by Rios, J.L, Recio, M.C, Giner, R.M, Manez, S

“…This paper reviews the literature on recent research on the chemical composition and pharmacological activities of saffron (Crocus sativus) and its active…”
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Effects of plant alkylphenols on cytokine production, tyrosine nitration and inflammatory damage in the efferent phase of contact hypersensitivity by Olmos, A, Giner, R M, Recio, M C, Rios, J L, Cerdá‐Nicolás, J M, Máñez, S

“…Background and purpose: The phenolic compounds isoprenylhydroquinone glucoside (IHG), 3,5‐dicaffeoylquinic acid (DCA), and its methyl ester (DCE) have…”
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Cocoa Polyphenols and Their Potential Benefits for Human Health by Andújar, I., Recio, M. C., Giner, R. M., Ríos, José Luis

“…This paper compiles the beneficial effects of cocoa polyphenols on human health, especially with regard to cardiovascular and inflammatory diseases, metabolic…”
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Anti-inflammatory profile of dehydrocostic acid, a novel sesquiterpene acid with a pharmacophoric conjugated diene by Hernández, V., Máñez, S., Recio, M.C., Giner, R.M., Ríos, J.L.

“…Sesquiterpene acids are natural products that, in contrast with the thoroughly studied sesquiterpene lactones, have received little pharmacological attention…”
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Bcl‐2 is a negative regulator of interleukin‐1β secretion in murine macrophages in pharmacological‐induced apoptosis by Escandell, JM, Recio, MC, Giner, RM, Máñez, S, Ríos, JL

“…BACKGROUND AND PURPOSE Cucurbitacin R, a natural anti‐inflammatory product, has been shown to exhibit activity against both adjuvant‐induced arthritis and…”
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Pharmacological approach to the pro- and anti-inflammatory effects of Ranunculus sceleratus L by Prieto, J.M, Recio, M.C, Giner, R.M, Máñez, S, Rı́os, J.L

“…Ranunculus sceleratus is a widespread species with unique toxicological and pharmacological activities. The present study seeks to assess this species’…”
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Chromatographic Determination of Cyanoglycosides Prunasin and Amygdalin in Plant Extracts Using a Porous Graphitic Carbon Column by Berenguer-Navarro, V, Giner-Galván, R. M, Grané-Teruel, N, Arrazola-Paternina, G

“…The determination of cyanogenic compounds in plants is often performed by HPLC. However, in this analysis, interferences due to compounds in the matrix, such…”
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Demethylnobiletin inhibits delayed‐type hypersensitivity reactions, human lymphocyte proliferation and cytokine production by Bas, E, Recio, M C, Giner, R M, Máñez, S, López‐Ginés, C, Gil‐Benso, R, Ríos, J L

“…Background and purpose: Our aim was to examine the effect of demethylnobiletin on various experimental models of delayed‐type hypersensitivity (DTH) reactions…”
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Shikonin promotes intestinal wound healing in vitro via induction of TGF-β release in IEC-18 cells by Andújar, I., Ríos, J.L., Giner, R.M., Recio, M.C.

“…[Display omitted] The intestinal barrier is a complex system with a dynamic structure that is designed for the maintenance of homeostasis in healthy…”
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In vitro and in vivo effects of Ranunculus peltatus subsp. baudotii methanol extract on models of eicosanoid production and contact dermatitis by Prieto, J.M, Recio, M.C, Giner, R.M, Schinella, G.R, Máñez, S, Ríos, J.L

“…Ranunculus (Crowfoot) species are numerous and they are all reputed to be counter-irritants and are used in several topical conditions. In order to study the…”
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Elucidating the aryl hydrocarbon receptor antagonism from a chemical-structural perspective by Goya-Jorge, E., Doan, T.Q., Scippo, M.L., Muller, M., Giner, R.M., Barigye, S.J., Gozalbes, R.

“…The aryl hydrocarbon receptor (AhR) plays an important role in several biological processes such as reproduction, immunity and homoeostasis. However, little is…”
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Anti-inflammatory activity of unusual lupane saponins from Bupleurum fruticescens by Just, M J, Recio, M C, Giner, R M, Cuéllar, M J, Máñez, S, Bilia, A R, Ríos, J L

“…Extracts from Bupleurum fruticescens were examined for oral and topical anti-inflammatory activities. The BuOH extract proved to be active against carrageenan…”
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Structural requirements for the anti-inflammatory activity of natural triterpenoids by Recio, M C, Giner, R M, Máñez, S, Ríos, J L

“…In order to establish the possible relationship between their chemical structures and pharmacological properties, the oral and topical anti-inflammatory…”
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New Acetophenone Glucosides Isolated from Extracts of Helichrysum italicum with Antiinflammatory Activity by SALA, Araceli, RECIO, María del Carmen, GINER, Rosa María, MáñEZ, Salvador, RíOS, José-Luis

“…Three new acetophenone glucosides (4-6), three known aglycons (1-3), and a benzo-gamma-pyrone glucoside (7) were isolated from the CH(2)Cl(2), EtOAc, and BuOH…”
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Structural considerations on the iridoids as anti-inflammatory agents by Recio, M C, Giner, R M, Máñez, S, Ríos, J L

“…Twelve iridoid glycosides have been evaluated for their anti-inflammatory activity on two models: the carrageenan-induced mouse paw edema and the TPA-induced…”
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In vivo activity of pseudoguaianolide sesquiterpene lactones in acute and chronic inflammation by Recio, M.C., Giner, R.M., Uriburu, L., Máñez, S., Cerdá, M., De La Fuente, J.R., Ríos, J.L.

“…The pseudoguaianolide sesquiterpene lactones 4-α-O-acetyl-pseudoguaian-6β-olide (1), hymenin (2), ambrosanolide (3), tetraneurin A (4), parthenin (5), hysterin…”
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