Search Results - "Ginell, S L"

The Productive Conformation of Arachidonic Acid Bound to Prostaglandin Synthase by Malkowski, M. G., Ginell, S. L., Smith, W. L., Garavito, R. M.

“…Prostaglandin H synthase-1 and -2 (PGHS-1 and -2) catalyze the committed step in prostaglandin synthesis and are targets for nonsteroidal anti-inflammatory…”
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Crystal and molecular structure of a DNA fragment containing a 2-aminoadenine modification: the relationship between conformation, packing, and hydration in Z-DNA hexamers by Schneider, Bohdan, Ginell, Stephan L, Jones, Roger, Gaffney, Barbara, Berman, Helen M

“…The crystal and molecular structure of d(CGUA'CG)2 (where A' is 2-aminoadenine) has been determined and refined to an R factor of 13.8% for data 8.0-1.3 A. The…”
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Low temperature structures of dCpG-proflavine. Conformational and hydration effects by Schneider, B., Ginell, S.L., Berman, H.M.

“…The structure of the complex of dCpG with proflavine was determined using x-ray data taken at -130 degrees C (low temperature) and at -2 degrees C (cold…”
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Crystal and molecular structure of a DNA fragment: d(CGTGAATTCACG) by Narayana, Narendra, Ginell, Stephan L, Russu, Irina M, Berman, Helen M

“…The crystal structure of the dodecanucleotide d(CGTGAATTCACG) has been determined to a resolution of 2.7 A and refined to an R factor of 17.0% for 1532…”
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Crystallization and preliminary X‐ray diffraction studies of the human adenovirus serotype 2 proteinase with peptide cofactor by Keefe, Lisa J., Ginell, Stephan L., Westbrook, Edwin M., Anderson, Carl W.

“…Recombinant human adenovirus serotype 2 proteinase (both native and selenomethionine‐substituted) has been crystallized in the presence of the serotype 12,…”
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Aldose and aldehyde reductases: structure-function studies on the coenzyme and inhibitor-binding sites by El-Kabbani, O, Old, S E, Ginell, S L, Carper, D A

“…To identify the structural features responsible for the differences in coenzyme and inhibitor specificities of aldose and aldehyde reductases. The crystal…”
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Towards protein-crystal centering using second-harmonic generation (SHG) microscopy by Kissick, David J., Dettmar, Christopher M., Becker, Michael, Mulichak, Anne M., Cherezov, Vadim, Ginell, Stephan L., Battaile, Kevin P., Keefe, Lisa J., Fischetti, Robert F., Simpson, Garth J.

“…The potential of second‐harmonic generation (SHG) microscopy for automated crystal centering to guide synchrotron X‐ray diffraction of protein crystals was…”
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Crystal and molecular structure of a new Z-DNA crystal form: d[CGT(2-NH2-A)CG] and its platinated derivative by Parkinson, Gary N, Arvanitis, Georgia M, Lessinger, Leslie, Ginell, Stephan L, Jones, Roger, Gaffney, Barbara, Berman, Helen M

“…The three-dimensional structure of d[CGTA'CG], where A' = [2-NH2-A], was determined to atomic (1.35 A) resolution by single isomorphous replacement. The…”
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Crystal Structure of a Mispaired Dodecamer, d(CGAGAATTC(O6Me)GCG)2, Containing a Carcinogenic O6-Methylguanine by Ginell, Stephan L, Vojtechovsky, Jaroslav, Gaffney, Barbara, Jones, Roger, Berman, Helen M

“…The crystal structure of the synthetic deoxydodecamer d(CGAGAATTC(O6Me)GCG)2 has been determined and refined to an R-factor of 16.9% with data up to 2.9-A…”
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Structure of porcine aldehyde reductase holoenzyme by El-Kabbani, Ossama, Judge, Ken, Ginell, Stephan L, Myles, Dean A. A, DeLucas, Lawrence J, Flynn, T. Geoffrey

“…Aldehyde reductase, a member of the aldo-keto reductase superfamily, catalyzes the NADPH-dependent reduction of a variety of aldehydes to their corresponding…”
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Crystal and molecular structure of a DNA duplex containing the carcinogenic lesion O6-methylguanine by Ginell, Stephan L, Kuzmich, Sandra, Jones, Roger A, Berman, Helen M

“…The crystal and molecular structure of the first DNA duplex containing the carcinogenic lesion O6MeG has been determined to a resolution of 1.9 A and refined…”
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Mutational and X-ray Crystallographic Analysis of the Interaction of Dihomo-γ-linolenic Acid with Prostaglandin Endoperoxide H Synthases by Thuresson, Elizabeth D., Malkowski, Michael G., Lakkides, Karen M., Rieke, Caroline Jill, Mulichak, Anne M., Ginell, Stephen L., Garavito, R. Michael, Smith, William L.

“…Prostaglandin endoperoxide H synthases-1 and -2 (PGHSs) catalyze the committed step in prostaglandin biosynthesis. Both isozymes can oxygenate a variety of…”
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The Structural Biology Center 19ID undulator beamline: facility specifications and protein crystallographic results by Rosenbaum, Gerd, Alkire, Randy W, Evans, Gwyndaf, Rotella, Frank J, Lazarski, Krzystof, Zhang, Rong Guang, Ginell, Stephan L, Duke, Norma, Naday, Istvan, Lazarz, Jack, Molitsky, Michael J, Keefe, Lisa, Gonczy, John, Rock, Larry, Sanishvili, Ruslan, Walsh, Martin A, Westbrook, Edwin, Joachimiak, Andrzej

“…The 19ID undulator beamline of the Structure Biology Center has been designed and built to take full advantage of the high flux, brilliance and quality of…”
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Approaches to isozyme-specific inhibitors. 16. A novel methyl-C5' covalent adduct of L-ethionine and .beta.,.gamma.-imido-ATP as a potent multisubstrate inhibitor of rat methionine adenosyltransferases by Vrudhula, Vivekananda M, Kappler, Francis, Afshar, Carol, Ginell, Stephan L, Lessinger, Leslie, Hampton, Alexander

“…N6,N6-Dibenzoyl-2',3'-O-isopropylideneadenosine, which is readily synthesized by one-pot 5'-O-trimethylsilylation, N6-benzoylation, and desilylation, was…”
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Workshop on high-throughput macromolecular crystallography by Keefe, L. J., Ginell, S. L., Howard, A. J.

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Temperature and cryoprotectant influence secondary quinone binding position in bacterial reaction centers by Pokkuluri, P.Raj, Laible, Philip D, Crawford, Adam E, Mayfield, Joy F, Yousef, Mohammed A, Ginell, Stephan L, Hanson, Deborah K, Schiffer, Marianne

“…We have determined the first de novo position of the secondary quinone Q B in the Rhodobacter sphaeroides reaction center (RC) using phases derived by the…”
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Crystal structure of a mispaired dodecamer, d(CGAGAATTC(O{sup 6}Me)GCG){sub 2}, containing a carcinogenic O{sup 6}-methylguanine by Schneider, B., Ginell, S. L., Jones, R., Gaffney, B., Berman, H. M., Rutgers

“…The crystal structure of the synthetic deoxydodecamer d(CGAGAATTC(O{sup 6}Me)GCG)2 has been determined and refined to an R-factor of 16.9% with data up to…”
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Crystal structure of a mispaired dodecamer, d(CGAGAATTC(O super(6)Me)GCG) sub(2), containing a carcinogenic O super(6)-methylguanine by Ginell, S L, Vojtechovsky, J, Gaffney, B, Jones, R, Berman, H M

“…The crystal structure of the synthetic deoxydodecamer d(CGAGAATTC(O super(6)Me)GCG) sub(2) has been determined and refined to an R-factor of 16.9% with data up…”
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Low temperature structures of dCpG-proflavine by Schneider, B., Ginell, S. L., Berman, H. M., Center for Mechanistic Biology and Biotechnology, Rutgers Univ

“…The structure of the complex of dCpG with proflavine was determined using x-ray data taken at -130 degrees C (low temperature) and at -2 degrees C (cold…”
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Crystal and molecular structure of a DNA duplex containing the carcinogenic lesion O super(6)-methylguanine by Ginell, S L, Kuzmich, S, Jones, R A, Berman, H M

“…The crystal and molecular structure of the first DNA duplex containing the carcinogenic lesion O super(6)MeG has been determined to a resolution of 1.9…”
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