Search Results - "Gine, Eva"

CART19-BE-01: A Multicenter Trial of ARI-0001 Cell Therapy in Patients with CD19+ Relapsed/Refractory Malignancies by Ortíz-Maldonado, Valentín, Rives, Susana, Castellà, Maria, Alonso-Saladrigues, Anna, Benítez-Ribas, Daniel, Caballero-Baños, Miguel, Baumann, Tycho, Cid, Joan, Garcia-Rey, Enric, Llanos, Cristina, Torrebadell, Montserrat, Villamor, Neus, Giné, Eva, Díaz-Beyá, Marina, Guardia, Laia, Montoro, Mercedes, Català, Albert, Faura, Anna, González, E. Azucena, Español-Rego, Marta, Klein-González, Nela, Alsina, Laia, Castro, Pedro, Jordan, Iolanda, Fernández, Sara, Ramos, Federico, Suñé, Guillermo, Perpiñá, Unai, Canals, Josep M., Lozano, Miquel, Trias, Esteve, Scalise, Andrea, Varea, Sara, Sáez-Peñataro, Joaquín, Torres, Ferran, Calvo, Gonzalo, Esteve, Jordi, Urbano-Ispizua, Álvaro, Juan, Manel, Delgado, Julio

“…We evaluated the administration of ARI-0001 cells (chimeric antigen receptor T cells targeting CD19) in adult and pediatric patients with relapsed/refractory…”
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Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia by Quesada, Víctor, Conde, Laura, Villamor, Neus, Ordóñez, Gonzalo R, Jares, Pedro, Bassaganyas, Laia, Ramsay, Andrew J, Beà, Sílvia, Pinyol, Magda, Martínez-Trillos, Alejandra, López-Guerra, Mónica, Colomer, Dolors, Navarro, Alba, Baumann, Tycho, Aymerich, Marta, Rozman, María, Delgado, Julio, Giné, Eva, Hernández, Jesús M, González-Díaz, Marcos, Puente, Diana A, Velasco, Gloria, Freije, José M P, Tubío, José M C, Royo, Romina, Gelpí, Josep L, Orozco, Modesto, Pisano, David G, Zamora, Jorge, Vázquez, Miguel, Valencia, Alfonso, Himmelbauer, Heinz, Bayés, Mónica, Heath, Simon, Gut, Marta, Gut, Ivo, Estivill, Xavier, López-Guillermo, Armando, Puente, Xose S, Campo, Elías, López-Otín, Carlos

“…Carlos López-Otín, Elías Campo and colleagues report exome sequencing of tumor and normal samples from 105 individuals with chronic lymphocytic leukemia (CLL)…”
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Genomic and transcriptomic profiling reveals distinct molecular subsets associated with outcomes in mantle cell lymphoma by Yi, Shuhua, Yan, Yuting, Jin, Meiling, Bhattacharya, Supriyo, Wang, Yi, Wu, Yiming, Yang, Lu, Gine, Eva, Clot, Guillem, Chen, Lu, Yu, Ying, Zou, Dehui, Wang, Jun, Phan, An T, Cui, Rui, Li, Fei, Sun, Qi, Zhai, Qiongli, Wang, Tingyu, Yu, Zhen, Liu, Lanting, Liu, Wei, Lyv, Rui, Sui, Weiwei, Huang, Wenyang, Xiong, Wenjie, Wang, Huijun, Li, Chengwen, Xiao, Zhijian, Hao, Mu, Wang, Jianxiang, Cheng, Tao, Bea, Silvia, Herrera, Alex F, Danilov, Alexey, Campo, Elias, Ngo, Vu N, Qiu, Lugui, Wang, Lili

“…Mantle cell lymphoma (MCL) is a phenotypically and genetically heterogeneous malignancy in which the genetic alterations determining clinical indications are…”
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Safety, Pharmacokinetics, and Preliminary Clinical Activity of Inotuzumab Ozogamicin, a Novel Immunoconjugate for the Treatment of B-Cell Non-Hodgkin's Lymphoma: Results of a Phase I Study by Advani, Anjali, Coiffier, Bertrand, Czuczman, Myron S, Dreyling, Martin, Foran, James, Gine, Eva, Gisselbrecht, Christian, Ketterer, Nicolas, Nasta, Sunita, Rohatiner, Ama, Schmidt-Wolf, Ingo G H, Schuler, Martin, Sierra, Jorge, Smith, Mitchell R, Verhoef, Gregor, Winter, Jane N, Boni, Joseph, Vandendries, Erik, Shapiro, Mark, Fayad, Luis

“…PURPOSE Inotuzumab ozogamicin (CMC-544) is an antibody-targeted chemotherapy agent composed of a humanized anti-CD22 antibody conjugated to calicheamicin, a…”
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Decoding the DNA Methylome of Mantle Cell Lymphoma in the Light of the Entire B Cell Lineage by Queirós, Ana C., Beekman, Renée, Vilarrasa-Blasi, Roser, Duran-Ferrer, Martí, Clot, Guillem, Merkel, Angelika, Raineri, Emanuele, Russiñol, Nuria, Castellano, Giancarlo, Beà, Sílvia, Navarro, Alba, Kulis, Marta, Verdaguer-Dot, Núria, Jares, Pedro, Enjuanes, Anna, Calasanz, María José, Bergmann, Anke, Vater, Inga, Salaverría, Itziar, van de Werken, Harmen J.G., Wilson, Wyndham H., Datta, Avik, Flicek, Paul, Royo, Romina, Martens, Joost, Giné, Eva, Lopez-Guillermo, Armando, Stunnenberg, Hendrik G., Klapper, Wolfram, Pott, Christiane, Heath, Simon, Gut, Ivo G., Siebert, Reiner, Campo, Elías, Martín-Subero, José I.

“…We analyzed the in silico purified DNA methylation signatures of 82 mantle cell lymphomas (MCL) in comparison with cell subpopulations spanning the entire B…”
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Ibrutinib combined with immunochemotherapy with or without autologous stem-cell transplantation versus immunochemotherapy and autologous stem-cell transplantation in previously untreated patients with mantle cell lymphoma (TRIANGLE): a three-arm, randomised, open-label, phase 3 superiority trial of the European Mantle Cell Lymphoma Network by Dreyling, Martin, Doorduijn, Jeanette, Giné, Eva, Jerkeman, Mats, Walewski, Jan, Hutchings, Martin, Mey, Ulrich, Riise, Jon, Trneny, Marek, Vergote, Vibeke, Shpilberg, Ofer, Gomes da Silva, Maria, Leppä, Sirpa, Jiang, Linmiao, Stilgenbauer, Stephan, Kerkhoff, Andrea, Jachimowicz, Ron D, Celli, Melania, Hess, Georg, Arcaini, Luca, Visco, Carlo, van Meerten, Tom, Wirths, Stefan, Zinzani, Pier Luigi, Novak, Urban, Herhaus, Peter, Benedetti, Fabio, Sonnevi, Kristina, Hanoun, Christine, Hänel, Matthias, Dierlamm, Judith, Pott, Christiane, Klapper, Wolfram, Gözel, Döndü, Schmidt, Christian, Unterhalt, Michael, Ladetto, Marco, Hoster, Eva

“…Adding ibrutinib to standard immunochemotherapy might improve outcomes and challenge autologous stem-cell transplantation (ASCT) in younger (aged 65 years or…”
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The academic point-of-care anti-CD19 chimeric antigen receptor T-cell product varnimcabtagene autoleucel (ARI-0001 cells) shows efficacy and safety in the treatment of relapsed/refractory B-cell non-Hodgkin lymphoma by Martínez-Cibrián, Núria, Ortiz-Maldonado, Valentín, Español-Rego, Marta, Blázquez, Andrea, Cid, Joan, Lozano, Miquel, Magnano, Laura, Giné, Eva, Correa, Juan G, Mozas, Pablo, Rodríguez-Lobato, Luis Gerardo, Rivero, Andrea, Montoro-Lorite, Mercedes, Ayora, Pilar, Navarro, Sergio, Alserawan, Leticia, González-Navarro, E Azucena, Castellà, Maria, Sánchez-Castañón, María, Cabezón, Raquel, Benítez-Ribas, Daniel, Setoaín, Xavier, Rodríguez, Sonia, Brillembourg, Helena, Varea, Sara, Olesti, Eulalia, Guillén, Elena, Sáez-Peñataro, Joaquín, de Larrea, Carlos Fernández, López-Guillermo, Armando, Pascal, Mariona, Urbano-Ispizua, Álvaro, Juan, Manel, Delgado, Julio

“…Varnimcabtagene autoleucel (var-cel) is an academic anti-CD19 chimeric antigen receptor (CAR) product used for the treatment of non-Hodgkin lymphoma (NHL) in…”
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Mutations in the RAS-BRAF-MAPK-ERK pathway define a specific subgroup of patients with adverse clinical features and provide new therapeutic options in chronic lymphocytic leukemia by Giménez, Neus, Martínez-Trillos, Alejandra, Montraveta, Arnau, Lopez-Guerra, Mónica, Rosich, Laia, Nadeu, Ferran, Valero, Juan G, Aymerich, Marta, Magnano, Laura, Rozman, Maria, Matutes, Estella, Delgado, Julio, Baumann, Tycho, Gine, Eva, González, Marcos, Alcoceba, Miguel, Terol, M José, Navarro, Blanca, Colado, Enrique, Payer, Angel R, Puente, Xose S, López-Otín, Carlos, Lopez-Guillermo, Armando, Campo, Elias, Colomer, Dolors, Villamor, Neus

“…Mutations in genes of the RAS-BRAF-MAPK-ERK pathway have not been fully explored in patients with chronic lymphocytic leukemia. We, therefore, analyzed the…”
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Outcomes of younger patients with mantle cell lymphoma experiencing late relapse (>24 months): the LATE-POD study by Malinverni, Chiara, Bernardelli, Andrea, Glimelius, Ingrid, Mirandola, Massimo, Smedby, Karin E., Tisi, Maria Chiara, Giné, Eva, Albertsson-Lindblad, Alexandra, Marin-Niebla, Ana, Di Rocco, Alice, Moita, Filipa, Sciarra, Roberta, Bašić-Kinda, Sandra, Hess, Georg, Ohler, Anke, Eskelund, Christian W., Re, Alessandro, Ferrarini, Isacco, Kolstad, Arne, Räty, Riikka, Quaglia, Francesca Maria, Eyre, Toby A., Scapinello, Greta, Stefani, Piero Maria, Morello, Lucia, Nassi, Luca, Hohaus, Stefan, Ragaini, Simone, Zilioli, Vittorio Ruggero, Bruna, Riccardo, Cocito, Federica, Arcari, Annalisa, Jerkeman, Mats, Visco, Carlo

“…•Patients with MCL experiencing late relapse benefit from BTK-inhibitors over chemoimmunotherapies.•Overall, chemoimmunotherapies as second-line treatment are…”
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Results of ARI‐0001 CART19 cell therapy in patients with relapsed/refractory CD19‐positive acute lymphoblastic leukemia with isolated extramedullary disease by Ortiz‐Maldonado, Valentín, Alonso‐Saladrigues, Anna, Español‐Rego, Marta, Martínez‐Cibrián, Nuria, Faura, Anna, Magnano, Laura, Català, Albert, Benítez‐Ribas, Daniel, Giné, Eva, Díaz‐Beyá, Marina, Correa, Juan Gonzalo, Rovira, Montserrat, Montoro‐Lorite, Mercedes, Martínez‐Roca, Alexandra, Rodríguez‐Lobato, Luis Gerardo, Cabezón, Raquel, Cid, Joan, Lozano, Miquel, Garcia‐Rey, Enric, Conde, Nuria, Pedrals, Georgina, Rozman, María, Torrebadell, Montserrat, Setoain, Xavier, Rodríguez, Sonia, Esteve, Jordi, Pascal, Mariona, Urbano‐Ispizua, Álvaro, Juan, Manel, Delgado, Julio, Rives, Susana

“…We evaluated outcomes of 18 patients with isolated extramedullary disease (iEMD) relapsed/refractory (R/R) B‐cell acute lymphoblastic leukemia (B‐ALL) treated…”
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The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome by Duran-Ferrer, Martí, Clot, Guillem, Nadeu, Ferran, Beekman, Renée, Baumann, Tycho, Nordlund, Jessica, Marincevic-Zuniga, Yanara, Lönnerholm, Gudmar, Rivas-Delgado, Alfredo, Martín, Silvia, Ordoñez, Raquel, Castellano, Giancarlo, Kulis, Marta, Queirós, Ana C, Lee, Seung-Tae, Wiemels, Joseph, Royo, Romina, Puiggrós, Montserrat, Lu, Junyan, Giné, Eva, Beà, Sílvia, Jares, Pedro, Agirre, Xabier, Prosper, Felipe, López-Otín, Carlos, Puente, Xosé S, Oakes, Christopher C, Zenz, Thorsten, Delgado, Julio, López-Guillermo, Armando, Campo, Elías, Martín-Subero, José Ignacio

“…We report a systematic analysis of the DNA methylation variability in 1,595 samples of normal cell subpopulations and 14 tumor subtypes spanning the entire…”
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Factors associated with the clinical outcome of patients with relapsed/refractory CD19+ acute lymphoblastic leukemia treated with ARI-0001 CART19-cell therapy by Ortiz-Maldonado, Valentín, Rives, Susana, Español-Rego, Marta, Alonso-Saladrigues, Anna, Montoro, Mercedes, Magnano, Laura, Giné, Eva, Pascal, Mariona, Díaz-Beyá, Marina, Castella, Maria, Català, Albert, Faura, Anna, Rodríguez-Lobato, Luis Gerardo, Oliver-Caldes, Aina, Martínez-Roca, Alexandra, Rovira, Montserrat, González-Navarro, E Azucena, Ortega, Juan Ramón, Cid, Joan, Lozano, Miquel, Garcia-Rey, Enric, Fernández, Sara, Castro, Pedro, Jordan, Iolanda, Villamor, Neus, Aymerich, Marta, Torrebadell, Montserrat, Deyà, Àngela, Fernández de Larrea, Carlos, Benitez-Ribas, Daniel, Trias, Esteve, Varea, Sara, Calvo, Gonzalo, Esteve, Jordi, Urbano-Ispizua, Alvaro, Juan, Manel, Delgado, Julio

“…Correspondence to Dr Julio Delgado; jdelgado@clinic.cat ; Dr Manel Juan; mjuan@clinic.cat The prognosis of patients with relapsed/refractory (R/R) acute…”
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P1391: VARNIMCABTAGENE AUTOLEUCEL (VAR‐CEL) IN RELAPSED/ REFRACTORY CD19+ NON‐HODGKIN LYMPHOMA by Martinez‐Cibrian, Nuria, Ortiz‐Maldonado, Valentín, Español‐Rego, Marta, Benitez‐Ribas, Daniel, Cid, Joan, Lozano, Miquel, Navarro, Sergio, Magnano, Laura, Gine, Eva, Saldarriaga, Juan Gonzalo Correa, Mozas, Pablo, Lobato, Luis Gerardo Rodríguez, Brillembourg, Helena, Montoro, Mercedes, Ayora, Pilar, Alserawan, Leticia, Martínez Roca, Alexandra, Lopez‐Guillermo, Armando, Urbano Ispizua, Avaro, Juan, Manel, Pascal, Mariona, Delgado, Julio

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P1394: RITUXIMAB BASED LYMPHODEPLETION MAY INCREASE ENGRAFTMENT AND EFFICACY OF SECOND INFUSIONS OF CART19 CELLS IN B‐CELL ACUTE LYMPHOBLASTIC LEUKEMIA by Ortiz‐Maldonado, Valentín, Martinez‐Cibrian, Nuria, Español‐Rego, Marta, Muñoz‐Sanchez, Guillermo, Navarro, Sergio, Alserawan, Leticia, Castella, Maria, Benitez‐Ribas, Daniel, Magnano, Laura, Gine, Eva, Rodríguez Lobato, Luis Gerardo, Martínez Roca, Alexandra, Brillembourg, Helena, Montoro, Mercedes, Ayora, Pilar, Fernandez de Larrea, Carlos, Pascal, Mariona, Esteve, Jordi, Urbano Ispizua, Avaro, Juan, Manel, Delgado, Julio

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Landscape of somatic mutations and clonal evolution in mantle cell lymphoma by Beà, Sílvia, Valdés-Mas, Rafael, Navarro, Alba, Salaverria, Itziar, Martín-Garcia, David, Jares, Pedro, Giné, Eva, Pinyol, Magda, Royo, Cristina, Nadeu, Ferran, Conde, Laura, Juan, Manel, Clot, Guillem, Vizán, Pedro, Di Croce, Luciano, Puente, Diana A., López-Guerra, Mónica, Moros, Alexandra, Roue, Gael, Aymerich, Marta, Villamor, Neus, Colomo, Lluís, Martínez, Antonio, Valera, Alexandra, Martín-Subero, José I., Amador, Virginia, Hernández, Luis, Rozman, Maria, Enjuanes, Anna, Forcada, Pilar, Muntañola, Ana, Hartmann, Elena M., Calasanz, María J., Rosenwald, Andreas, Ott, German, Hernández-Rivas, Jesús M., Klapper, Wolfram, Siebert, Reiner, Wiestner, Adrian, Wilson, Wyndham H., Colomer, Dolors, López-Guillermo, Armando, López-Otín, Carlos, Puente, Xose S., Campo, Elías

“…Mantle cell lymphoma (MCL) is an aggressive tumor, but a subset of patients may follow an indolent clinical course. To understand the mechanisms underlying…”
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Risk factors for mortality in patients with acute leukemia and bloodstream infections in the era of multiresistance by Garcia-Vidal, Carolina, Cardozo-Espinola, Celia, Puerta-Alcalde, Pedro, Marco, Francesc, Tellez, Adrian, Agüero, Daiana, Romero-Santana, Francisco, Díaz-Beyá, Marina, Giné, Eva, Morata, Laura, Rodríguez-Núñez, Olga, Martinez, Jose Antonio, Mensa, Josep, Esteve, Jordi, Soriano, Alex

“…We assess the epidemiology and risk factors for mortality of bloodstream infection (BSI) in patients with acute leukemia (AL). Prospectively collected data of…”
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Histological Transformation and Progression in Follicular Lymphoma: A Clonal Evolution Study by Kridel, Robert, Chan, Fong Chun, Mottok, Anja, Boyle, Merrill, Farinha, Pedro, Tan, King, Meissner, Barbara, Bashashati, Ali, McPherson, Andrew, Roth, Andrew, Shumansky, Karey, Yap, Damian, Ben-Neriah, Susana, Rosner, Jamie, Smith, Maia A, Nielsen, Cydney, Giné, Eva, Telenius, Adele, Ennishi, Daisuke, Mungall, Andrew, Moore, Richard, Morin, Ryan D, Johnson, Nathalie A, Sehn, Laurie H, Tousseyn, Thomas, Dogan, Ahmet, Connors, Joseph M, Scott, David W, Steidl, Christian, Marra, Marco A, Gascoyne, Randy D, Shah, Sohrab P

“…Follicular lymphoma (FL) is an indolent, yet incurable B cell malignancy. A subset of patients experience an increased mortality rate driven by two distinct…”
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Mutational Landscape and Tumor Burden Assessed by Cell-free DNA in Diffuse Large B-Cell Lymphoma in a Population-Based Study by Rivas-Delgado, Alfredo, Nadeu, Ferran, Enjuanes, Anna, Casanueva-Eliceiry, Sebastián, Mozas, Pablo, Magnano, Laura, Castrejón de Anta, Natalia, Rovira, Jordina, Dlouhy, Ivan, Martín, Silvia, Osuna, Miguel, Rodríguez, Sonia, Simó, Marc, Pinyol, Magda, Baumann, Tycho, Beà, Silvia, Balagué, Olga, Delgado, Julio, Villamor, Neus, Setoain, Xavier, Campo, Elías, Giné, Eva, López-Guillermo, Armando

“…We analyzed the utility of cell-free DNA (cfDNA) in a prospective population-based cohort to determine the mutational profile, assess tumor burden, and…”
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Molecular Subsets of Mantle Cell Lymphoma Defined by the IGHV Mutational Status and SOX11 Expression Have Distinct Biologic and Clinical Features by NAVARRO, Alba, CLOT, Guillem, PINYOL, Magda, PUIG, Xavier, PALOMERO, Jara, VEGLIANTE, Maria Carmela, AMADOR, Virgina, MARTINEZ-TRILLOS, Alejandra, STEFANCIKOVA, Lenka, WIESTNER, Adrian, WILSON, Wyndham, POTT, Christiane, ROYO, Cristina, CALASANZ, Maria José, TRIM, Nicola, ERBER, Wendy, SANDER, Birgitta, OTT, German, ROSENWALD, Andreas, COLOMER, Dolors, GINE, Eva, SIEBERT, Reiner, LOPEZ-GUILLERMO, Armando, JARES, Pedro, STAMATOPOULOS, Kostas, BEA, Sílvia, CAMPO, Elias, HADZIDIMITRIOU, Anastasia, AGATHANGELIDIS, Andreas, BIKOS, Vasilis, DARZENTAS, Nikos, PAPADAKI, Theodora, SALAVERRIA, Itziar

“…Mantle cell lymphoma (MCL) is a heterogeneous disease with most patients following an aggressive clinical course, whereas others having an indolent behavior…”
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SOX11/PRDX2 axis modulates redox homeostasis and chemoresistance in aggressive mantle cell lymphoma by De Bolòs, Anna, Sureda-Gómez, Marta, Carreras-Caballé, Maria, Rodríguez, Marta-Leonor, Clot, Guillem, Beà, Silvia, Giné, Eva, Campo, Elias, Balsas, Patricia, Amador, Virginia

“…Mantle cell lymphoma (MCL) is an incurable B-cell neoplasm characterized by an aggressive behavior, short responses to conventional therapies and SOX11…”
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