Search Results - "Gine, Elena"
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The Immune System through the Lens of Alcohol Intake and Gut Microbiota
Published in International journal of molecular sciences (13-07-2021)“…The human gut is the largest organ with immune function in our body, responsible for regulating the homeostasis of the intestinal barrier. A diverse, complex…”
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C/EBPβ Regulates TFAM Expression, Mitochondrial Function and Autophagy in Cellular Models of Parkinson's Disease
Published in International journal of molecular sciences (11-01-2023)“…Parkinson's disease (PD) is a neurodegenerative disorder that results from the degeneration of dopaminergic neurons in the ( ). Since there are only…”
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Long-Term Effects of Intermittent Adolescent Alcohol Exposure in Male and Female Rats
Published in Frontiers in behavioral neuroscience (28-11-2017)“…Alcohol is a serious public health concern that has a differential impact on individuals depending upon age and sex. Patterns of alcohol consumption have…”
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Nalmefene is effective at reducing alcohol seeking, treating alcohol‐cocaine interactions and reducing alcohol‐induced histone deacetylases gene expression in blood
Published in British journal of pharmacology (01-08-2016)“…Background and Purpose The opioid antagonist nalmefene (selincro®) was approved for alcohol‐related disorders by the European Medicines Agency in 2013…”
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Effects of Adolescent Intermittent Alcohol Exposure on the Expression of Endocannabinoid Signaling-Related Proteins in the Spleen of Young Adult Rats
Published in PloS one (23-09-2016)“…Intermittent alcohol exposure is a common pattern of alcohol consumption among adolescents and alcohol is known to modulate the expression of the…”
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Inhibition of Receptor Protein Tyrosine Phosphatase β/ζ Reduces Alcohol Intake in Rats
Published in Alcoholism, clinical and experimental research (01-05-2020)“…Background Pleiotrophin (PTN) and midkine (MK) are cytokines that are up‐regulated in the prefrontal cortex (PFC) after alcohol administration and have been…”
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Histone Deacetylase Gene Expression Following Binge Alcohol Consumption in Rats and Humans
Published in Alcoholism, clinical and experimental research (01-10-2015)“…Background Alcohol binge drinking is one of the most common patterns of excessive alcohol use and recent data would suggest that histone deacetylases (HDACs)…”
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Dissecting operant alcohol self‐administration using saccharin‐fading procedure
Published in Neuropsychopharmacology reports (01-03-2023)“…Background Although alcohol use disorder is a complex human pathology, the use of animal models represents an opportunity to study some aspects of this…”
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Red Bull® energy drink increases consumption of higher concentrations of alcohol
Published in Addiction biology (01-09-2018)“…Mixing alcohol with caffeinated energy drinks is a common practice, especially among young people. In humans, the research on this issue has mainly focused on…”
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10
A spontaneous deletion of α-Synuclein is associated with an increase in CB1 mRNA transcript and receptor expression in the hippocampus and amygdala: Effects on alcohol consumption
Published in Synapse (New York, N.Y.) (01-06-2013)“…ABSTRACT α‐Synuclein (α‐syn) protein and endocannabinoid CB1 receptors are primarily located in presynaptic terminals. An association between α‐syn and CB1…”
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11
Multiple organ inflammatory response to portosystemic shunt in the rat
Published in Cytokine (Philadelphia, Pa.) (01-12-2011)“…► Portosystemic shunting in the rat could induce a systemic inflammatory response. ► Inflammatory mediators were assayed in the splanchnic area and lungs. ► An…”
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Consequences of early life stress on the expression of endocannabinoid-related genes in the rat brain
Published in Behavioural pharmacology (01-09-2014)“…The endocannabinoid system is involved in several physiological and pathological states including anxiety, depression, addiction and other neuropsychiatric…”
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13
Classic psychedelics and alcohol use disorders: A systematic review of human and animal studies
Published in Addiction biology (01-11-2022)“…Classic psychedelics refer to substances such as lysergic acid diethylamide (LSD), psilocybin, ayahuasca, and mescaline, which induce altered states of…”
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The Women Neuroscientists in the Cajal School
Published in Frontiers in neuroanatomy (16-07-2019)“…At the beginning of the 20th century, in view of the growing international recognition of Santiago Ramón y Cajal, the Spanish authorities took some important…”
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The genetics of self-reported trait impulsivity: Contribution of catecholaminergic gene variants in European ancestry individuals
Published in Personality and individual differences (01-01-2023)“…Increased trait impulsivity is a core element in several mental disorders. Given the durable and consistent nature of trait impulsivity, studies have explored…”
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Common single nucleotide variants underlying drug addiction: more than a decade of research
Published in Addiction biology (01-09-2015)“…Drug‐related phenotypes are common complex and highly heritable traits. In the last few years, candidate gene (CGAS) and genome‐wide association studies (GWAS)…”
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Women Neuroscientist Disciples of Pío del Río-Hortega: the Cajal School Spreads in Europe and South America
Published in Frontiers in neuroanatomy (10-05-2021)“…Pio del Rio-Hortega was not only the discoverer of the microglia and oligodendroglia but also possibly the most prolific mentor of all Santiago Ramon y Cajal’s…”
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Developmental Hypothyroidism Increases the Expression of Kainate Receptors in the Hippocampus and the Sensitivity to Kainic Acid-Induced Seizures in the Rat
Published in Endocrinology (Philadelphia) (01-07-2010)“…Thyroid hormones are essential for normal brain development, and multiple alterations at behavioral, cognitive, cellular, and molecular levels have been…”
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The CB1 receptor is required for the establishment of the hyperlocomotor phenotype in developmentally-induced hypothyroidism in mice
Published in Neuropharmacology (01-04-2017)“…Alterations in motor functions are well-characterized features observed in humans and experimental animals with thyroid hormone dysfunctions during…”
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Risky alcohol consumption in young people is associated with the fatty acid amide hydrolase gene polymorphism C385A and affective rating of drug pictures
Published in Molecular genetics and genomics : MGG (01-06-2014)“…Drug addiction is a complex disease with overlapping stages and influenced by multiple environmental and genetic factors. In addition to neurobiological…”
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