Search Results - "Gimotty, P. A."

Melanoma progression exhibits a significant impact on connexin expression patterns in the epidermal tumor microenvironment by Haass, Nikolas K, Ripperger, D, Wladykowski, E, Dawson, P, Gimotty, P. A, Blome, C, Fischer, F, Schmage, P, Moll, I, Brandner, Johanna M

“…Melanoma depends on, interacts with and reacts to the stroma in which it is embedded, including fibroblasts, extracellular matrix, endothelial cells and immune…”
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Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation by Kumar, S M, Liu, S, Lu, H, Zhang, H, Zhang, P J, Gimotty, P A, Guerra, M, Guo, W, Xu, X

“…There is enormous interest to target cancer stem cells (CSCs) for clinical treatment because these cells are highly tumorigenic and resistant to chemotherapy…”
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Long-term outcomes to neoadjuvant pembrolizumab based on pathological response for patients with resectable stage III/IV cutaneous melanoma by Sharon, C.E., Tortorello, G.N., Ma, K.L., Huang, A.C., Xu, X., Giles, L.R., McGettigan, S., Kreider, K., Schuchter, L.M., Mathew, A.J., Amaravadi, R.K., Gimotty, P.A., Miura, J.T., Karakousis, G.C., Mitchell, T.C.

“…While neoadjuvant immunotherapy for melanoma has shown promising results, the data have been limited by a relatively short follow-up time, with most studies…”
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Diagnostic accuracy of IgG‐specific versus polyspecific enzyme‐linked immunoassays in heparin‐induced thrombocytopenia: a systematic review and meta‐analysis by Husseinzadeh, H. D., Gimotty, P. A., Pishko, A. M., Buckley, M., Warkentin, T. E., Cuker, A.

“…Essentials Immunoassay specificity varies in heparin‐induced thrombocytopenia (HIT) testing. This meta‐analysis examined 9 studies that tested samples by both…”
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MEK inhibition affects STAT3 signaling and invasion in human melanoma cell lines by Vultur, A, Villanueva, J, Krepler, C, Rajan, G, Chen, Q, Xiao, M, Li, L, Gimotty, P A, Wilson, M, Hayden, J, Keeney, F, Nathanson, K L, Herlyn, M

“…Elevated activity of the mitogen-activated protein kinase (MAPK) signaling cascade is found in the majority of human melanomas and is known to regulate…”
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Prevalence of and risk factors for cerebral microbleeds among adult patients with haemophilia A or B by Husseinzadeh, H., Chiasakul, T., Gimotty, P. A., Pukenas, B., Wolf, R., Kelty, M., Chiang, E., Fogarty, P. F., Cuker, A.

“…Introduction Cerebral microbleeds (CMBs) represent clinically silent haemorrhagic events. Cerebral microbleeds (CMBs) portend negative neurovascular and…”
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Cellular senescence checkpoint function determines differential Notch1-dependent oncogenic and tumor-suppressor activities by Kagawa, S, Natsuizaka, M, Whelan, K A, Facompre, N, Naganuma, S, Ohashi, S, Kinugasa, H, Egloff, A M, Basu, D, Gimotty, P A, Klein-Szanto, A J, Bass, A J, Wong, K-K, Diehl, J A, Rustgi, A K, Nakagawa, H

“…Notch activity regulates tumor biology in a context-dependent and complex manner. Notch may act as an oncogene or a tumor-suppressor gene even within the same…”
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Long-term event-free survivors after high-dose therapy and autologous stem-cell transplantation for low-grade follicular lymphoma by ANDREADIS, C, SCHUSTER, S. J, DOWNS, L. H, MANGAN, P. A, CUNNINGHAM, K. A, HUMMEL, K. A, GIMOTTY, P. A, SIEGEL, D. L, GLATSTEIN, E, STADTMAUER, E. A, CHONG, E. A, SVOBODA, J, LUGER, S. M, PORTER, D. L, TSAI, D. E, NASTA, S. D, ELSTROM, R. L, GOLDSTEIN, S. C

“…Although follicular lymphoma (FL) is generally responsive to conventional-dose chemotherapy, improved survival in patients with this disease has been difficult…”
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Correction of human hemophilia A whole blood abnormalities with a novel bypass agent: zymogen-like FXa(I16L) by George, L A, Thalji, N K, Raffini, L J, Gimotty, P A, Camire, R M

“…Approximately 30% of hemophilia A (HA) and 5% of hemophilia B patients develop inhibitors to protein replacement therapy, and this is the major cause of…”
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Interventional therapies and in‐hospital outcomes in acute coronary syndromes complicated by von Willebrand disease by Fogarty, P. F., Blair, A., Vega, R., Matthai, W. H., Gimotty, P. A.

“…Introduction von Willebrand disease (VWD) is one of the most common inherited bleeding disorders. Aim Investigate the impact of the VWD bleeding tendency on…”
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Intratumoral T Cells, Recurrence, and Survival in Epithelial Ovarian Cancer by Zhang, Lin, Conejo-Garcia, Jose R, Katsaros, Dionyssios, Gimotty, Phyllis A, Massobrio, Marco, Regnani, Giorgia, Makrigiannakis, Antonis, Gray, Heidi, Schlienger, Katia, Liebman, Michael N, Rubin, Stephen C, Coukos, George

“…The outcome of treatment in advanced ovarian cancer can vary considerably among patients with similar clinical and pathological findings. In this…”
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Correction of human hemophilia A whole blood abnormalities with a novel bypass agent: zymogen‐like FXaI16L by George, L. A., Thalji, N. K., Raffini, L. J., Gimotty, P. A., Camire, R. M.

“…Summary Background Approximately 30% of hemophilia A (HA) and 5% of hemophilia B patients develop inhibitors to protein replacement therapy, and this is the…”
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The effect of patient and physician reminders on use of screening mammography in a health maintenance organization: Results of a randomized controlled trial by Burack, Robert C., Gimotty, Phyllis A., George, Julie, Simon, Michael S., Dews, Peter, Moncrease, Anita

“…BACKGROUND Despite its demonstrated efficacy in reducing breast carcinoma mortality, screening mammography remains underutilized and its promotion in the…”
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Developmental role of the SNF1-related kinase Hunk in pregnancy-induced changes in the mammary gland by Gardner, H P, Belka, G K, Wertheim, G B, Hartman, J L, Ha, S I, Gimotty, P A, Marquis, S T, Chodosh, L A

“…The steroid hormones 17 beta-estradiol and progesterone play a central role in the pathogenesis of breast cancer and regulate key phases of mammary gland…”
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The effect of patient reminders on the use of screening mammography in an urban health department primary care setting by SIMON, Michael S, GIMOTTY, Phyllis A, MONCREASE, Anita, DEWS, Peter, BURACK, Robert C

“…Mammography screening continues to be under-utilized, especially among women from lower socioeconomic groups. In order to determine whether having direct…”
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INT2 and ERBB2 amplification and ERBB2 expression in breast tumors from patients with different outcomes by PAULEY, R. J, GIMOTTY, P. A, PAINE, T. J, DAWSON, P. J, WOLMAN, S. R

“…The relationships of INT2 and ERBB2 amplification and of ERBB2 overexpression in primary breast tumors to prognostic factors, recurrence, and survival have…”
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Protective effect of chorionic gonadotropin on DMBA-induced mammary carcinogenesis by Russo, I H, Koszalka, M, Gimotty, P A, Russo, J

“…The effect of the placental hormone chorionic gonadotropin (hCG) on 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary tumours was studied in young virgin…”
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The Effect of Primary Care Training on Patient Satisfaction Ratings by Bialor, Bruce D., Gimotty, Phyllis A., Poses, Roy M., Fagan, Mark J.

“…This study examines the association between type of internal medicine training and satisfaction ratings among 509 patients who visited the clinic of an urban…”
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Chloralose alters circulatory response to alpha-receptor stimulation and blockade by Covert, R F, Drummond, W H, Gimotty, P A

“…Chloralose anesthesia is commonly used in animals for cardiovascular research despite limited data on possible receptor-drug interactions. To investigate…”
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How reminders given to patients and physicians affected Pap smear use in a health maintenance organization : Results of a randomized controlled trial by BURACK, R. C, GIMOTTY, P. A, GEORGE, J, MCBRIDE, S, MONCREASE, A, SIMON, M. S, DEWS, P, COOMBS, J

“…Despite its effectiveness as a method of controlling cervical carcinoma, the use of Pap smear testing remains incomplete, and its promotion in the primary care…”
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