Robotically assisted laparoscopic radical prostatectomy induces lower tissue trauma than radical retropubic prostatectomy

Robotically assisted laparoscopic radical prostatectomy induces lower tissue trauma than radical retropubic prostatectomy

To compare tissue trauma between Retropubic Radical Prostatectomy and Robotically Assisted Laparoscopic Radical Prostatectomy by inflammatory mediators. Serum samples from 40 patients submitted to RALP and 20 patients submitted to RRP were withdrawn at four different time points. The cytokines IL-4,...

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Bibliographic Details
Published in:Journal of robotic surgery Vol. 15; no. 1; pp. 147 - 151
Main Authors: Quinto, Denise, Reis, Sabrina T., Zampolli, Lucca Juvele, Pimenta, Ruan, Guimarães, Vanessa R., Viana, Nayara I., dos Santos, Gabriel A., Gimenez, Mario P., Leite, Katia R., Zampolli, Hamilton, da Cruz, José Arnaldo S., Srougi, Miguel, Passerotti, Carlo C.
Format: Journal Article
Language:English
Published: London Springer London 01-02-2021
Springer Nature B.V
Subjects:
Brief Communication
Cytokines
Laparoscopy
Medicine
Medicine & Public Health
Minimally Invasive Surgery
Patients
Plasma
Prostate cancer
Robotic surgery
Software
Surgery
Tumor necrosis factor-TNF
Urological surgery
Urology
United States > US
Cytokines
Prostate cancer
TNF
Surgery
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Summary:To compare tissue trauma between Retropubic Radical Prostatectomy and Robotically Assisted Laparoscopic Radical Prostatectomy by inflammatory mediators. Serum samples from 40 patients submitted to RALP and 20 patients submitted to RRP were withdrawn at four different time points. The cytokines IL-4, IL-8, IL-6, IL-1B, IL-10 and TNF-α were detected using ELISA/Multiplex assays and xMAP—Luminex®. With both techniques, IL-10 and IL-6 were higher in T4 than in T1–T3 ( p  = 0.001). IL-10 and IL-6 were higher in T4 in open surgery than in robotic surgery ( p  = 0.000 and p  = 0.001, respectively). Compared with both groups, IL-6 and IL-10 were higher in T4 in open surgery than in robotic surgery. Thus, we can postulate that RALP causes less tissue trauma than classical RRP, as indicated by the more limited increase in inflammatory mediators such as IL-6 and IL-10.
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ISSN:1863-2483
1863-2491
DOI:10.1007/s11701-020-01150-y