Search Results - "Gimenes, Sarah N.C."
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Antitumoral Potential of Lansbermin-I, a Novel Disintegrin from Porthidium lansbergii lansbergii Venom on Breast Cancer Cells
Published in Current topics in medicinal chemistry (01-01-2019)“…Disintegrins from snake venoms bind with high specificity cell surface integrins, which are important pharmacological targets associated with cancer…”
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Inflammatory Reaction Induced by Two Metalloproteinases Isolated from Bothrops atrox Venom and by Fragments Generated from the Hydrolysis of Basement Membrane Components
Published in Toxins (02-02-2020)“…Snake venom metalloproteinases (SVMPs) play an important role in local tissue damage of snakebite patients, mostly by hydrolysis of basement membrane (BM)…”
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Observation of Bothrops atrox Snake Envenoming Blister Formation from Five Patients: Pathophysiological Insights
Published in Toxins (13-11-2021)“…In the Brazilian Amazon, snakebites are frequent, and patients develop tissue damage with blisters sometimes observed in the proximity of the wound. Antivenoms…”
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Cross-reactivity and inhibition myotoxic effects induced by Bothrops snake venoms using specific polyclonal anti-BnSP7 antibodies
Published in Biologicals (01-11-2017)“…Polyclonal antibodies raised in Balb-c mice against BnSP-7, a Lys-49 phospholipase A2, were used to measure cross reactivity against other snake venoms. Using…”
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Bothrops pauloensis snake venom toxins: the search for new therapeutic models
Published in Current topics in medicinal chemistry (01-01-2015)“…Snake venoms constitute a mixture of bioactive components that are involved not only in envenomation pathophysiology but also in the development of new drugs…”
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