Search Results - "Gimble, J.M."

Multipotential human adipose-derived stromal stem cells exhibit a perivascular phenotype in vitro and in vivo by Zannettino, A.C.W., Paton, S., Arthur, A., Khor, F., Itescu, S., Gimble, J.M., Gronthos, S.

“…Mesenchymal stem‐like cells identified in different tissues reside in a perivascular niche. In the present study, we investigated the putative niche of…”
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Stromal stem cells from adipose tissue and bone marrow of age-matched female donors display distinct immunophenotypic profiles by Pachón-Peña, G., Yu, G., Tucker, A., Wu, X., Vendrell, J., Bunnell, B.A., Gimble, J.M.

“…Adipose tissue is composed of lipid‐filled mature adipocytes and a heterogeneous stromal vascular fraction (SVF) population of cells. Similarly, the bone…”
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The function of adipocytes in the bone marrow stroma: an update by Gimble, J.M., Robinson, C.E., Wu, X., Kelly, K.A.

“…The adipocyte is the most abundant stromal cell phenotype in adult human bone marrow. Four hypotheses may explain their function. First, adipocytes may serve a…”
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Circadian Rhythm of Osteocalcin in the Maxillomandibular Complex by Gafni, Y., Ptitsyn, A.A., Zilberman, Y., Pelled, G., Gimble, J.M., Gazit, D.

“…The human body displays central circadian rhythms of activity. Recent findings suggest that peripheral tissues, such as bone, possess their own circadian…”
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Adipose-derived adult stem cells: isolation, characterization, and differentiation potential by Gimble, J.M., Guilak, F.

“…Adipose tissue is an abundant, accessible, and replenishable source of adult stem cells that can be isolated from liposuction waste tissue by collagenase…”
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MicroRNA regulation of stem cell differentiation and diseases of the bone and adipose tissue: Perspectives on miRNA biogenesis and cellular transcriptome by Martin, E.C., Qureshi, A.T., Dasa, V., Freitas, M.A., Gimble, J.M., Davis, T.A.

“…MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression through targeting and suppression of mRNAs. miRNAs have been under investigation for…”
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Biophysical cues enhance myogenesis of human adipose derived stem/stromal cells by Yilgor Huri, P., Cook, C.A., Hutton, D.L., Goh, B.C., Gimble, J.M., DiGirolamo, D.J., Grayson, W.L.

“…•Biochemical stimulation alone induces weak myogenic response of ASCs.•Dynamic uniaxial strain significantly increases efficiency of ASC myogenesis.•ASCs have…”
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Yield of human adipose-derived adult stem cells from liposuction aspirates by Aust, L., Devlin, B., Foster, S.J., Halvorsen, Y.D.C., Hicok, K., du Laney, T., Sen, A., Willingmyre, G.D., Gimble, J.M.

“…Primary cultures of isolated human adipose-derived adult stem (ADAS) cells are multipotent and differentiate in vitro along the adipocyte, chondrocyte,…”
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Characterization of neuronal/glial differentiation of murine adipose-derived adult stromal cells by Safford, K.M., Safford, S.D., Gimble, J.M., Shetty, A.K., Rice, H.E.

“…Neural tissue has limited capacity for intrinsic repair after injury, and the identification of alternate sources of neuronal stem cells has broad clinical…”
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Is there a therapeutic opportunity to either prevent or treat osteopenic disorders by inhibiting marrow adipogenesis? by Nuttall, M.E, Gimble, J.M

“…Bone marrow stromal cells can undergo adipogenesis or osteoblastogenesis in vitro and in vivo. This review explores the stromal cell’s differentiation…”
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Human adenovirus Ad-36 induces adipogenesis via its E4 orf-1 gene by Rogers, P.M, Fusinski, K.A, Rathod, M.A, Loiler S, Pasarica, M, Shaw, M.K, Kilroy, G, Sutton, G.M, McAllister, E.J, Mashtalir, N

“…Objective: Understanding the regulation of adipocyte differentiation by cellular and extracellular factors is crucial for better management of chronic…”
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Circadian biology and sleep: missing links in obesity and metabolism by Gimble, J.M, Bray, M.S, Young, A

“…This supplement highlights key talks presented at the Pennington Symposium. The collected papers provide a state of the art review of circadian biology at the…”
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Adipose-derived stromal cells--their utility and potential in bone formation by Halvorsen, Y.C, Wilkison, W.O, Gimble, J.M

“…Many organs contain connective tissue or stromal cells and these cells play important roles in growth, development and tissue repair. Subcutaneous adipose…”
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Expression profile of mRNAs encoding core circadian regulatory proteins in human subcutaneous adipose tissue: correlation with age and body mass index by Wu, X, Xie, H, Yu, G, Hebert, T, Goh, B C, Smith, S R, Gimble, J M

“…Objective: Circadian mechanisms underlie the physiology of mammals as an adaptation to the earth's rotation on its axis. Highly conserved core circadian…”
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Competitive electroporation formulation for cell therapy by Flanagan, M, Gimble, J M, Yu, G, Wu, X, Xia, X, Hu, J, Yao, S, Li, S

“…Established cell transfection via nucleofection relies on nucleofection buffers with unknown and proprietary makeup due to trade secrecy, inhibiting the…”
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Beyond ‘baby fat’: adipose-derived stem cells are coming of age by Gimble, J.M.

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Beyond ‘baby fat’: adipose-derived stem cells are coming of age by Gimble, J.M., MD, PhD

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Frequency of stromal lineage colony forming units in bone marrow of peroxisome proliferator-activated receptor-α-null mice by Wu, X, Peters, J.M, Gonzalez, F.J, Prasad, H.S, Rohrer, M.D, Gimble, J.M

“…The bone marrow stroma, consisting of adipocytes, fibroblasts, and osteoblasts, develops from a multipotent mesenchymal progenitor. The recently described…”
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Characterization of Murine Bone Marrow and Spleen-Derived Stromal Cells: Analysis of Leukocyte Marker and Growth Factor mRNA Transcript Levels by Gimble, J.M., Pietrangeli, C., Henley, A., Dorheim, M.A., Silver, J., Namen, A., Takeichi, M., Goridis, C., Kincade, P.W.

“…Stromal cells are believed to regulate lympho-hematopoie- sis through direct cell-cell interactions and the release of growth factors. Many questions remain,…”
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Comparisons of hematopoietic support by adipose-derived and bone marrow-derived stroma by Storms, R.W., Green, P.D., Foster, S.J., Gimble, J.M.

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