Search Results - "Giménez, Neus"

Targeting IRAK4 disrupts inflammatory pathways and delays tumor development in chronic lymphocytic leukemia by Giménez, Neus, Schulz, Ralph, Higashi, Morihiro, Aymerich, Marta, Villamor, Neus, Delgado, Julio, Juan, Manel, López-Guerra, Mònica, Campo, Elias, Rosich, Laia, Seiffert, Martina, Colomer, Dolors

“…Interleukin-1 receptor-associated kinase 4 (IRAK4) plays a critical role in Toll-like receptor (TLR) signal transduction and innate immune responses…”
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Specific NOTCH1 antibody targets DLL4-induced proliferation, migration, and angiogenesis in NOTCH1-mutated CLL cells by López-Guerra, Mónica, Xargay-Torrent, Sílvia, Fuentes, Patricia, Roldán, Jocabed, González-Farré, Blanca, Rosich, Laia, Silkenstedt, Elisabeth, García-León, María J., Lee-Vergés, Eriong, Giménez, Neus, Giró, Ariadna, Aymerich, Marta, Villamor, Neus, Delgado, Julio, López-Guillermo, Armando, Puente, Xose S., Campo, Elias, Toribio, María L., Colomer, Dolors

“…Targeting Notch signaling has emerged as a promising therapeutic strategy for chronic lymphocytic leukemia (CLL), particularly in NOTCH1 -mutated patients. We…”
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Performance of SARS-CoV-2 Antigen-Detecting Rapid Diagnostic Tests for Omicron and Other Variants of Concern by Raïch-Regué, Dàlia, Muñoz-Basagoiti, Jordana, Perez-Zsolt, Daniel, Noguera-Julian, Marc, Pradenas, Edwards, Riveira-Muñoz, Eva, Giménez, Neus, Carabaza, Assumpta, Giménez, Francesc, Saludes, Verónica, Martró, Elisa, Robert, Neus, Blanco, Ignacio, Paredes, Roger, Ruiz, Lidia, Ballana, Ester, Clotet, Bonaventura, Blanco, Julià, Izquierdo-Useros, Nuria

“…The SARS-CoV-2 antigen-detecting rapid diagnostic test (Ag-RDTs) is an easy-to-use diagnostic tool to identify the contagious individuals and reduce the new…”
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Cyclin D1-CDK4 activity drives sensitivity to bortezomib in mantle cell lymphoma by blocking autophagy-mediated proteolysis of NOXA by Heine, Simon, Kleih, Markus, Giménez, Neus, Böpple, Kathrin, Ott, German, Colomer, Dolors, Aulitzky, Walter E, van der Kuip, Heiko, Silkenstedt, Elisabeth

“…Mantle cell lymphoma (MCL) is an aggressive B-non-Hodgkin lymphoma with generally poor outcome. MCL is characterized by an aberrantly high cyclin D1-driven…”
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Anterior Scleral Thickness Profile in Keratoconus by Burguera-Giménez, Neus, Díez-Ajenjo, María Amparo, Burguera, Noemí, Peris-Martínez, Cristina

“…Purpose: Considering that peripheral corneal thinning occurs in keratoconus (KC), the anterior scleral thickness (AST) profile was measured to compare…”
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Mutations in the RAS-BRAF-MAPK-ERK pathway define a specific subgroup of patients with adverse clinical features and provide new therapeutic options in chronic lymphocytic leukemia by Giménez, Neus, Martínez-Trillos, Alejandra, Montraveta, Arnau, Lopez-Guerra, Mónica, Rosich, Laia, Nadeu, Ferran, Valero, Juan G, Aymerich, Marta, Magnano, Laura, Rozman, Maria, Matutes, Estella, Delgado, Julio, Baumann, Tycho, Gine, Eva, González, Marcos, Alcoceba, Miguel, Terol, M José, Navarro, Blanca, Colado, Enrique, Payer, Angel R, Puente, Xose S, López-Otín, Carlos, Lopez-Guillermo, Armando, Campo, Elias, Colomer, Dolors, Villamor, Neus

“…Mutations in genes of the RAS-BRAF-MAPK-ERK pathway have not been fully explored in patients with chronic lymphocytic leukemia. We, therefore, analyzed the…”
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Subfoveal and Parafoveal Choroidal Thickening in Patients with Keratoconus Using the ETDRS Grid on Swept-Source OCT by Burguera-Giménez, Neus, Díez-Ajenjo, Mª. Amparo, Burguera, Noemí, Briceno-Lopez, Celeste, Peris-Martínez, Cristina

“…Introduction There is growing evidence that confirms morphological changes in the posterior structures in patients with keratoconus (KC); however, isolated…”
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Relationship between Choroidal Thickness and Anterior Scleral Thickness in Patients with Keratoconus by Burguera-Giménez, Neus, Díez-Ajenjo, M ª Amparo, Briceno-Lopez, Celeste, Burguera, Noemí, Luque-Cobija, M ª José, Peris-Martínez, Cristina

“…To evaluate the relationship between choroidal thickness (CT) and anterior scleral thickness (AST) in patients with subclinical keratoconus (SKC) and…”
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The link between anterior scleral thickness, corneal biomechanical response and ocular parameters by Giménez, Neus Burguera, Ajenjo, Amparo Díez, Burguera, Noemi, Cobija, Maria Josefa Luque, Lopez, Celeste Briceno, García‐Domene, Mª. Carmen, Peris‐Martínez, Cristina

“…Purpose: to assess anterior scleral thickness (AST) across diverse scleral meridians and to evaluate the relationship with corneal biomechanical response and…”
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Systems biology drug screening identifies statins as enhancers of current therapies in chronic lymphocytic leukemia by Gimenez, Neus, Tripathi, Rupal, Giró, Ariadna, Rosich, Laia, López-Guerra, Mònica, López-Oreja, Irene, Playa-Albinyana, Heribert, Arenas, Fabian, Mas, José Manuel, Pérez-Galán, Patricia, Delgado, Julio, Campo, Elias, Farrés, Judith, Colomer, Dolors

“…Chronic lymphocytic leukemia (CLL) is a B lymphoid malignancy highly dependent on the microenvironment. Despite new targeted therapies such as ibrutinib and…”
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The Link between Anterior Scleral Thickness, Corneal Biomechanical Response, and Ocular Parameters by Burguera-Giménez, Neus, Díez-Ajenjo, M. Amparo, Burguera, Noemí, Luque-Cobija, M. José, Peris-Martínez, Cristina

“…Abstract Introduction: This study aimed to assess anterior scleral thickness (AST) across diverse scleral meridians and to evaluate the relationship with…”
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Corneal Edema after Cataract Surgery by Briceno-Lopez, Celeste, Burguera-Giménez, Neus, García-Domene, M. Carmen, Díez-Ajenjo, M. Amparo, Peris-Martínez, Cristina, Luque, M. José

“…This systematic review investigates the prevalence and underlying causes of corneal edema following cataract surgery employing manual phacoemulsification. A…”
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Intracorneal ring segment in keratoconus: a model to predict visual changes induced by the surgery by Peña-García, Pablo, Vega-Estrada, Alfredo, Barraquer, Rafael I, Burguera-Giménez, Neus, Alio, Jorge L

“…We detected keratoconus cases with a significant potential for poor outcomes following intracorneal ring segment implantation (ICRS). We attempted to predict…”
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Multimodal Evaluation of Visual Function in Geographic Atrophy versus Normal Eyes by Burguera-Giménez, Noemi, García-Lázaro, Santiago, España-Gregori, Enrique, Gallego-Pinazo, Roberto, Burguera-Giménez, Neus, Rodríguez-Vallejo, Manuel, Jonna, Gowtham

“…To comprehensively evaluate visual function in eyes with geographic atrophy (GA) as compared to normal eyes. Sixty-three eyes from 63 patients ≥50 years old…”
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Targeting IRAK4 Disrupts Inflammatory Pathways and Delays Tumor Development in Chronic Lymphocytic Leukemia by Giménez Carabaza, Neus, Laia, Rosich, Ralph, Schulz, Morihiro, Higashi, Aymerich, Marta, Villamor, Neus, Delgado, Julio, Juan, Manel, Lopez-Guerra, Monica, Campo, Elias, Seiffert, Martina, Colomer, Dolors

“…Interleukin-1 receptor-associated kinase 4 (IRAK4) plays a critical role in Toll-like receptor (TLR) signal transduction and the innate immune responses…”
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Abstract LB-083: Targeting IRAK4 disrupts inflammatory pathways and tumor microenvironment in chronic lymphocytic leukemia regardless MYD88 mutational status by Rosich, Laia, Gimenez, Neus, Schulz, Ralph, Higashi, Morihiro, Aymerich, Marta, Lopez, Monica, Juan, Manel, Seiffert, Martina, Campo, Elias, Colomer, Dolors

“…Abstract BACKGROUND & AIM. Interleukin-1 receptor-associated kinase 4 (IRAK4) plays a critical role in Toll-like receptor (TLR) signal transduction and the…”
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Cyclin D1 Driven CDK4 Activity Is Responsible for Hypersensitivity to NOXA Inducing Combination Treatment in Mantle Cell Lymphoma (MCL) Cells by Heine, Simon, Silkenstedt, Elisabeth, Dengler, Michael A, Markus, Kleih, Ott, German, Giménez Carabaza, Neus, Dolors, Colomer, van der Kuip, Heiko, Aulitzky, Walter E.

“…Background: Mantle cell lymphoma (MCL) is an aggressive B-cell non-Hodgkin lymphoma with generally poor outcome. Hallmark of MCL is the t(11;14)(q13;q32)…”
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New drug discovery approaches targeting recurrent mutations in chronic lymphocytic leukemia by Tripathi, Rupal, Lee-Verges, Eriong, Higashi, Morihiro, Gimenez, Neus, Rosich, Laia, Lopez-Guerra, Monica, Colomer, Dolors

“…Next generation sequencing has provided a comprehensive understanding of the mutational landscape in chronic lymphocytic leukemia (CLL), and new drivers have…”
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Screening subclinical keratoconus with placido-based corneal indices by Ramos-López, Darío, Martínez-Finkelshtein, Andrei, Castro-Luna, Gracia M, Burguera-Gimenez, Neus, Vega-Estrada, Alfredo, Piñero, David, Alió, Jorge L

“…To assess in a sample of normal, keratoconic, and keratoconus (KC) suspect eyes the performance of a set of new topographic indices computed directly from the…”
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