Search Results - "Giltnane, JM"

Spatial analyses of immune cell infiltration in cancer: current methods and future directions. A report of the International Immuno‐Oncology Biomarker Working Group on Breast Cancer by Broeckx, Glenn, Jahangir, Chowdhury Arif, Verbandt, Sara, Thagaard, Jeppe, Khiroya, Reena, Abduljabbar, Khalid, Acosta Haab, Gabriela, Acs, Balazs, Almeida, Jonas S, Azmoudeh‐Ardalan, Farid, Badve, Sunil, Baharun, Nurkhairul Bariyah, Bheemaraju, Vydehi, Botinelly Mendonça Fujimoto, Luciana, Bouchmaa, Najat, Cheang, Maggie Chon U, Ciompi, Francesco, Cooper, Lee AD, Coosemans, An, Corredor, Germán, Dantas Portela, Flavio Luis, Demaria, Sandra, Dudgeon, Sarah N, Elghazawy, Mahmoud, Ely, Scott, Fernandez‐Martín, Claudio, Fox, Stephen B, Gallagher, William M, Giltnane, Jennifer M, Gonzalez‐Ericsson, Paula I, Grigoriadis, Anita, Halama, Niels, Harbhajanka, Aparna, Hardas, Alexandros, Hewitt, Stephen, Horlings, Hugo M, Hytopoulos, Evangelos, Irshad, Sheeba, Janssen, Emiel AM, Kahila, Mohamed, Kawaguchi, Kosuke, Kharidehal, Durga, Khramtsov, Andrey I, Kiraz, Umay, Kirtani, Pawan, Kodach, Liudmila L, Korski, Konstanty, Kovács, Anikó, Lang‐Schwarz, Corinna, Larsimont, Denis, Lennerz, Jochen K, Lerousseau, Marvin, Ly, Amy, Maley, Sai K, Manur Narasimhamurthy, Vidya, Marks, Douglas K, McDonald, Elizabeth S, Michiels, Stefan, Minhas, Fayyaz ul Amir Afsar, Mittal, Shachi, Mushtaq, Shamim, Nighat, Hussain, Papathomas, Thomas, Pinard, Christopher J, Pinto‐Cardenas, Juan Carlos, Pruneri, Giancarlo, Pusztai, Lajos, Rahman, Arman, Rajpoot, Nasir Mahmood, Rapoport, Bernardo Leon, Rau, Tilman T, Reis‐Filho, Jorge S, Ribeiro, Joana M, Rimm, David, Salto‐Tellez, Manuel, Sayed, Shahin, Siziopikou, Kalliopi P, Stenzinger, Albrecht, Sughayer, Maher A, Sur, Daniel, Symmans, Fraser, Tanaka, Sunao, Taxter, Timothy, Tejpar, Sabine, Teuwen, Jonas, Thompson, E Aubrey, Tramm, Trine, Verghese, Gregory E, Vieth, Michael, Wahab, Noorul, Walter, Thomas, Wen, Hannah Y, Yang, Wentao, Adams, Sylvia, Bartlett, John Mark Seaverns, Loibl, Sibylle, Savas, Peter, Loi, Sherene, Salgado, Roberto, Specht Stovgaard, Elisabeth

“…Modern histologic imaging platforms coupled with machine learning methods have provided new opportunities to map the spatial distribution of immune cells in…”
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Pitfalls in machine learning-based assessment of tumor-infiltrating lymphocytes in breast cancer: A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer by Thagaard, Jeppe, Broeckx, Glenn, Page, David B, Jahangir, Chowdhury Arif, Verbandt, Sara, Kos, Zuzana, Gupta, Rajarsi, Khiroya, Reena, Abduljabbar, Khalid, Acosta Haab, Gabriela, Acs, Balazs, Akturk, Guray, Almeida, Jonas S, Alvarado-Cabrero, Isabel, Amgad, Mohamed, Azmoudeh-Ardalan, Farid, Badve, Sunil, Baharun, Nurkhairul Bariyah, Balslev, Eva, Bellolio, Enrique R, Bheemaraju, Vydehi, Blenman, Kim Rm, Botinelly Mendonça Fujimoto, Luciana, Bouchmaa, Najat, Burgues, Octavio, Chardas, Alexandros, Chon U Cheang, Maggie, Ciompi, Francesco, Cooper, Lee Ad, Coosemans, An, Corredor, Germán, Dahl, Anders B, Dantas Portela, Flavio Luis, Deman, Frederik, Demaria, Sandra, Doré Hansen, Johan, Dudgeon, Sarah N, Ebstrup, Thomas, Elghazawy, Mahmoud, Fernandez-Martín, Claudio, Fox, Stephen B, Gallagher, William M, Giltnane, Jennifer M, Gnjatic, Sacha, Gonzalez-Ericsson, Paula I, Grigoriadis, Anita, Halama, Niels, Hanna, Matthew G, Harbhajanka, Aparna, Hart, Steven N, Hartman, Johan, Hauberg, Søren, Hewitt, Stephen, Hida, Akira I, Horlings, Hugo M, Husain, Zaheed, Hytopoulos, Evangelos, Irshad, Sheeba, Janssen, Emiel Am, Kahila, Mohamed, Kataoka, Tatsuki R, Kawaguchi, Kosuke, Kharidehal, Durga, Khramtsov, Andrey I, Kiraz, Umay, Kirtani, Pawan, Kodach, Liudmila L, Korski, Konstanty, Kovács, Anikó, Laenkholm, Anne-Vibeke, Lang-Schwarz, Corinna, Larsimont, Denis, Lennerz, Jochen K, Lerousseau, Marvin, Li, Xiaoxian, Ly, Amy, Madabhushi, Anant, Maley, Sai K, Manur Narasimhamurthy, Vidya, Marks, Douglas K, McDonald, Elizabeth S, Mehrotra, Ravi, Michiels, Stefan, Minhas, Fayyaz Ul Amir Afsar, Mittal, Shachi, Moore, David A, Mushtaq, Shamim, Nighat, Hussain, Papathomas, Thomas, Penault-Llorca, Frederique, Perera, Rashindrie D, Pinard, Christopher J, Pinto-Cardenas, Juan Carlos, Pruneri, Giancarlo, Pusztai, Lajos, Rahman, Arman, Rajpoot, Nasir Mahmood, Rapoport, Bernardo Leon, Rau, Tilman T, Reis-Filho, Jorge S

“…The clinical significance of the tumor-immune interaction in breast cancer is now established, and tumor-infiltrating lymphocytes (TILs) have emerged as…”
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Blimp-1 Orchestrates Plasma Cell Differentiation by Extinguishing the Mature B Cell Gene Expression Program by Shaffer, A.L., Lin, Kuo-I, Kuo, Tracy C., Yu, Xin, Hurt, Elaine M., Rosenwald, Andreas, Giltnane, Jena M., Yang, Liming, Zhao, Hong, Calame, Kathryn, Staudt, Louis M.

“…Blimp-1, a transcriptional repressor, drives the terminal differentiation of B cells to plasma cells. Using DNA microarrays, we found that introduction of…”
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Abstract GS3-05: Prospective optimization of estrogen receptor degradation yields ER ligands with variable capacities for ER transcriptional suppression by Metcalfe, C, Zhou, W, Guan, J, Daemen, A, Hafner, M, Blake, RA, Ingalla, E, Young, A, Oeh, J, De Bruyn, T, Ubhayakar, S, Chen, I, Giltnane, JM, Li, J, Wang, X, Sampath, D, Hager, JH, Friedman, LS

“…Abstract ER+ breast cancers can depend on ER signaling throughout disease progression, including after acquired resistance to existing endocrine agents,…”
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Abstract P5-04-07: GDC-9545: A novel ER antagonist and clinical candidate that combines desirable mechanistic and pre-clinical DMPK attributes by Metcalfe, C, Ingalla, E, Blake, RA, Chang, J, Daemen, A, De Bruyn, T, Giltnane, JM, Guan, J, Hafner, M, Hartman, S, Kategaya, L, Kleinheinz, T, Liang, J, Mody, V, Nannini, M, Oeh, J, Ubhayakar, S, Wertz, I, Young, A, Zbieg, J, Zhou, W, Sampath, D, Friedman, LS, Wang, X

“…Abstract ER+ breast cancers depend on ER signaling throughout disease progression, including after acquired resistance to existing endocrine agents, providing…”
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The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphoma by Rosenwald, Andreas, Wright, George, Wiestner, Adrian, Chan, Wing C, Connors, Joseph M, Campo, Elias, Gascoyne, Randy D, Grogan, Thomas M, Muller-Hermelink, H.Konrad, Smeland, Erlend B, Chiorazzi, Michael, Giltnane, Jena M, Hurt, Elaine M, Zhao, Hong, Averett, Lauren, Henrickson, Sarah, Yang, Liming, Powell, John, Wilson, Wyndham H, Jaffe, Elaine S, Simon, Richard, Klausner, Richard D, Montserrat, Emilio, Bosch, Francesc, Greiner, Timothy C, Weisenburger, Dennis D, Sanger, Warren G, Dave, Bhavana J, Lynch, James C, Vose, Julie, Armitage, James O, Fisher, Richard I, Miller, Thomas P, LeBlanc, Michael, Ott, German, Kvaloy, Stein, Holte, Harald, Delabie, Jan, Staudt, Louis M

“…We used gene expression profiling to establish a molecular diagnosis of mantle cell lymphoma (MCL), to elucidate its pathogenesis, and to predict the length of…”
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Abstract P6-10-02: MHC-II positive breast tumors are more immunogenic and may preferentially select for LAG-3-positive tumor immune infiltrates by Balko, JM, Loi, S, Giltnane, JM, Combs, S, Estrada, MV, Sanchez, V, Rimm, D, Sanders, ME, Salgado, R, Gomez, H, Johnson, DB

“…Abstract Background: Lymphocyte-activation gene 3 (LAG-3) is a T-cell checkpoint regulator and a current target in immunotherapy trials. LAG-3's main ligand is…”
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Abstract PD5-02: Not presented by Guerrero-Zotano, AL, Stricker, TP, Hutchinson, KE, Stover, DG, Formisano, L, Lee, K-M, Schwarz, LJ, Giltnane, JM, Jansen, VM, Gavila, J, Perez-Fidalgo, A, Lluch, A, Llombart, A, Bayar, MA, Michiels, S, André, F, Arnedos, M, Ruiz, A, Arteaga, CL

“…Abstract This abstract was not presented at the symposium…”
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Role of NF-κB in Cell Survival and Transcription of Latent Membrane Protein 1-Expressing or Epstein-Barr Virus Latency III-Infected Cells by CAHIR-MCFARLAND, Ellen D, CARTER, Kara, ROSENWALD, Andreas, GILTNANE, Jena M, HENRICKSON, Sarah E, STAUDT, Louis M, KIEFF, Elliott

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Signatures of the Immune Response by Shaffer, A.L, Rosenwald, Andreas, Hurt, Elaine M, Giltnane, Jena M, Lam, Lloyd T, Pickeral, Oxana K, Staudt, Louis M

“…A compendium of global gene expression measurements from DNA microarray analysis of immune cells identifies gene expression signatures defining various…”
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Abstract S3-03: Nuclear FGFR1 interaction with estrogen receptor (ER) α is associated with resistance to endocrine therapy in ER+/FGFR1-amplified breast cancer by Formisano, L, Young, CD, Bhola, NE, Bulen, B, Estrada, VM, Wagle, N, Van Allen, E, Red Brewer, ML, Jansen, VM, Guerrero, AL, Giltnane, JM, Strcker, T, Arteaga, CL

“…Abstract Background: Estrogen receptor (ER)-positive breast cancers (BC) initially respond to antiestrogens but eventually become hormone-independent and…”
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Abstract PD3-1: Serial next generation sequencing (NGS) of poor prognosis luminal tumors across treatment history reveals both de novo and acquired alterations potentially associated with endocrine resistance by Giltnane, JM, Balko, JM, Wang, K, Kuba, MG, Mehndi, M, Stricker, TP, Sanders, ME, Yelensky, R, Stephens, PJ, Miller, V, Arteaga, CL

“…Abstract Cancer therapies exert selective pressure on genomically heterogeneous breast cancers and may select for alterations in genes associated with drug…”
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Abstract S6-01: JAK2 amplifications are enriched in triple negative breast cancers (TNBCs) after neoadjuvant chemotherapy and predict poor prognosis by Balko, JM, Giltnane, JM, Schwarz, LJ, Sanders, ME, Wang, K, Harris, LN, Lin, NU, Miller, VA, Stephens, PJ, Yelensky, R, Pinto, JA, Gomez, H, Arteaga, CL

“…Abstract Janus-kinase 2 (JAK2) is a receptor-coupled tyrosine kinase which transmits cytokine-mediated signals to the STAT pathway to drive signals of…”
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Growth Suppression by Acute Promyelocytic Leukemia-Associated Protein PLZF Is Mediated by Repression of c-myc Expression by McConnell, Melanie J, Chevallier, Nathalie, Berkofsky-Fessler, Windy, Giltnane, Jena M, Malani, Rupal B, Staudt, Louis M, Licht, Jonathan D

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