Search Results - "Gilquin, Bernard"

Structure of bacteriophage SPP1 head-to-tail connection reveals mechanism for viral DNA gating by Lhuillier, Sophie, Gallopin, Matthieu, Gilquin, Bernard, Brasilès, Sandrine, Lancelot, Nathalie, Letellier, Guillaume, Gilles, Mathilde, Dethan, Guillaume, Orlova, Elena V, Couprie, Joël, Tavares, Paulo, Zinn-Justin, Sophie

“…In many bacterial viruses and in certain animal viruses, the double-stranded DNA genome enters and exits the capsid through a portal gatekeeper. We report a…”
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Characterization of a Highly Conserved Binding Site of Mlh1 Required for Exonuclease I-Dependent Mismatch Repair by Dherin, Claudine, Gueneau, Emeric, Francin, Mathilde, Nunez, Marcela, Miron, Simona, Liberti, Sascha Emilie, Rasmussen, Lene Juel, Zinn-Justin, Sophie, Gilquin, Bernard, Charbonnier, Jean-Baptiste, Boiteux, Serge

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The Ig-like Structure of the C-Terminal Domain of Lamin A/C, Mutated in Muscular Dystrophies, Cardiomyopathy, and Partial Lipodystrophy by Krimm, Isabelle, Östlund, Cecilia, Gilquin, Bernard, Couprie, Joël, Hossenlopp, Paul, Mornon, Jean-Paul, Bonne, Gisèle, Courvalin, Jean-Claude, Worman, Howard J, Zinn-Justin, Sophie

“…Lamins are nuclear intermediate filaments that, together with lamin-associated proteins, maintain nuclear shape and provide a structural support for…”
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Orthosteric binding of ρ-Da1a, a natural peptide of snake venom interacting selectively with the α1A-adrenoceptor by Maïga, Arhamatoulaye, Merlin, Jon, Marcon, Elodie, Rouget, Céline, Larregola, Maud, Gilquin, Bernard, Fruchart-Gaillard, Carole, Lajeunesse, Evelyne, Marchetti, Charles, Lorphelin, Alain, Bellanger, Laurent, Summers, Roger J, Hutchinson, Dana S, Evans, Bronwyn A, Servent, Denis, Gilles, Nicolas

“…ρ-Da1a is a three-finger fold toxin from green mamba venom that is highly selective for the α1A-adrenoceptor. This toxin has atypical pharmacological…”
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The Carboxyl-terminal Nucleoplasmic Region of MAN1 Exhibits a DNA Binding Winged Helix Domain by Caputo, Sandrine, Couprie, Joël, Duband-Goulet, Isabelle, Kondé, Emilie, Lin, Feng, Braud, Sandrine, Gondry, Muriel, Gilquin, Bernard, Worman, Howard J., Zinn-Justin, Sophie

“…MAN1 is an integral protein of the inner nuclear membrane that interacts with nuclear lamins and emerin, thus playing a role in nuclear organization. It also…”
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Experimentally Based Model of a Complex between a Snake Toxin and the α7 Nicotinic Receptor by Fruchart-Gaillard, Carole, Gilquin, Bernard, Antil-Delbeke, Stéphanie, Le Novère, Nicolas, Tamiya, Toru, Corringer, Pierre-Jean, Changeux, Jean-Pierre, Ménez, André, Servent, Denis

“…To understand how snake neurotoxins interact with nicotinic acetylcholine receptors, we have elaborated an experimentally based model of the α-cobratoxin-α7…”
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Structural Characterization of the LEM Motif Common to Three Human Inner Nuclear Membrane Proteins by Laguri, Cédric, Gilquin, Bernard, Wolff, Nicolas, Romi-Lebrun, Régine, Courchay, Karine, Callebaut, Isabelle, Worman, Howard J., Zinn-Justin, Sophie

“…Background: Integral membrane proteins of the inner nuclear membrane are involved in chromatin organization and postmitotic reassembly of the nucleus. The…”
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A Variable Residue in the Pore of Kv1 Channels Is Critical for the High Affinity of Blockers from Sea Anemones and Scorpions by Gilquin, Bernard, Braud, Sandrine, Eriksson, Mats A.L., Roux, Benoît, Bailey, Timothy D., Priest, Birgit T., Garcia, Maria L., Ménez, André, Gasparini, Sylvaine

“…Animal toxins are associated with well defined selectivity profiles; however the molecular basis for this property is not understood. To address this issue we…”
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Solution structure of the region 51–160 of human KIN17 reveals an atypical winged helix domain by Carlier, Ludovic, Couprie, Joël, le Maire, Albane, Guilhaudis, Laure, Milazzo‐Segalas, Isabelle, Courçon, Marie, Moutiez, Mireille, Gondry, Muriel, Davoust, Daniel, Gilquin, Bernard, Zinn‐Justin, Sophie

“…Human KIN17 is a 45‐kDa eukaryotic DNA‐ and RNA‐binding protein that plays an important role in nuclear metabolism and in particular in the general response to…”
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Refined Structure of Charybdotoxin: Common Motifs in Scorpion Toxins and Insect Defensins by Bontems, Francois, Roumestand, Christian, Gilquin, Bernard, Ménez, André, Toma, Flavio

“…Conflicting three-dimensional structures of charybdotoxin (Chtx), a blocker of K$^+$ channels, have been previously reported. A high-resolution model depicting…”
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Analysis of side-chain organization on a refined model of charybdotoxin: structural and functional implications by Bontems, Francois, Gilquin, Bernard, Roumestand, Christian, Menez, Andre, Toma, Flavio

“…The spatial organization of side chains on a refined model of charybdotoxin is presented. First, the structural role of two groups of well-defined,…”
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Characterization of the Functional Epitope on the Urokinase Receptor by Gårdsvoll, Henrik, Gilquin, Bernard, Le Du, Marie Hélène, Ménèz, Andre, Jørgensen, Thomas J.D., Ploug, Michael

“…The high affinity interaction between the serine protease urokinase-type plasminogen activator (uPA) and its glycolipid-anchored receptor (uPAR) represents one…”
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Structural and functional consequences of the presence of a fourth disulfide bridge in the scorpion short toxins: Solution structure of the potassium channel inhibitor HsTX1 by SAVARIN, PHILIPPE, ROMI-LEBRUN, RÉGINE, ZINN-JUSTIN, SOPHIE, LEBRUN, BRUNO, NAKAJIMA, TERUMI, GILQUIN, BERNARD, MÉNEZ, ANDRÉ

“…We have determined the three-dimensional structure of the potassium channel inhibitor HsTX1, using nuclear magnetic resonance and molecular modeling. This…”
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Structure and Dynamics of the Anticodon Arm Binding Domain of Bacillus stearothermophilus Tyrosyl-tRNA Synthetase by Guijarro, J.Iñaki, Pintar, Alessandro, Prochnicka-Chalufour, Ada, Guez, Valérie, Gilquin, Bernard, Bedouelle, Hugues, Delepierre, Muriel

“…The structure of a recombinant protein, TyrRS(Δ4), corresponding to the anticodon arm binding domain of Bacillus stearothermophilus tyrosyl-tRNA synthetase,…”
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Structure of the BgK-Kv1.1 Complex Based on Distance Restraints Identified by Double Mutant Cycles by Gilquin, Bernard, Racapé, Judith, Wrisch, Anja, Visan, Violeta, Lecoq, Alain, Grissmer, Stephan, Ménez, André, Gasparini, Sylvaine

“…A structural model of BgK, a sea anemone toxin, complexed with the S5-S6 region of Kv1.1, a voltage-gated potassium channel, was determined by flexible docking…”
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Structure of the MutLα C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site by Gueneau, Emeric, Dherin, Claudine, Legrand, Pierre, Tellier-Lebegue, Carine, Gilquin, Bernard, Bonnesoeur, Pierre, Londino, Floriana, Quemener, Cathy, Le Du, Marie-Hélene, Márquez, Josan A, Moutiez, Mireille, Gondry, Muriel, Boiteux, Serge, Charbonnier, Jean-Baptiste

“…Defective mismatch-repair function is associated with hereditary nonpolyposis colorectal cancer (HNPCC), and mutations in the MLH1 subunit of the MutLα…”
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Molecular exploration of the α1A-adrenoceptor orthosteric site: Binding site definition for epinephrine, HEAT and prazosin by Maïga, Arhamatoulaye, Dupont, Mélanie, Blanchet, Guillaume, Marcon, Elodie, Gilquin, Bernard, Servent, Denis, Gilles, Nicolas

“…•Epinephrine interacts only moderately with the aspartic acid 106 in position 3.32.•Optimal experimental conditions reveal changes in prazosin and HEAT binding…”
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High affinity anchoring of the decoration protein pb10 onto the bacteriophage T5 capsid by Vernhes, Emeline, Renouard, Madalena, Gilquin, Bernard, Cuniasse, Philippe, Durand, Dominique, England, Patrick, Hoos, Sylviane, Huet, Alexis, Conway, James F., Glukhov, Anatoly, Ksenzenko, Vladimir, Jacquet, Eric, Nhiri, Naïma, Zinn-Justin, Sophie, Boulanger, Pascale

“…Bacteriophage capsids constitute icosahedral shells of exceptional stability that protect the viral genome. Many capsids display on their surface decoration…”
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Molecular exploration of the α(1A)-adrenoceptor orthosteric site: binding site definition for epinephrine, HEAT and prazosin by Maïga, Arhamatoulaye, Dupont, Mélanie, Blanchet, Guillaume, Marcon, Elodie, Gilquin, Bernard, Servent, Denis, Gilles, Nicolas

“…Despite the physiological and pharmacological importance of the α1A-adrenoreceptor, the mode of interactions of classical agonists and radioactive ligands with…”
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New α-adrenergic property for synthetic MTβ and CM-3 three-finger fold toxins from black mamba by Blanchet, Guillaume, Upert, Gregory, Mourier, Gilles, Gilquin, Bernard, Gilles, Nicolas, Servent, Denis

“…Despite their isolation more than fifteen years ago from the venom of the African mamba Dendroaspis polylepis, very few data are known on the functional…”
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