Search Results - "Gilmore, Michael"
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The persistent dilemma of microbial keratitis: Global burden, diagnosis, and antimicrobial resistance
Published in Survey of ophthalmology (01-05-2019)“…Microbial keratitis is a potentially blinding condition that must be treated emergently to preserve vision. Although long recognized as a significant cause of…”
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Friend turned foe: evolution of enterococcal virulence and antibiotic resistance
Published in Annual review of microbiology (01-01-2014)“…The enterococci are an ancient genus that evolved along with the tree of life. These intrinsically rugged bacteria are highly adapted members of the intestinal…”
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A biocultural approach to navigating conservation trade-offs through participatory methods
Published in Ecology and society (01-09-2022)“…The desire to simultaneously address the well-being of local people while also mitigating the destruction of ecosystems resulted in a variety of win-win…”
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4
Pathogenicity of Enterococci
Published in Microbiology spectrum (01-07-2019)“…Enterococci are unusually well adapted for survival and persistence in a variety of adverse environments, including on inanimate surfaces in the hospital…”
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Peptidoglycan recycling mediated by an ABC transporter in the plant pathogen Agrobacterium tumefaciens
Published in Nature communications (24-12-2022)“…During growth and division, the bacterial cell wall peptidoglycan (PG) is remodelled, resulting in the liberation of PG muropeptides which are typically…”
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A new class of synthetic retinoid antibiotics effective against bacterial persisters
Published in Nature (London) (05-04-2018)“…Synthetic retinoid compounds can kill both growing and persister MRSA cells by disrupting the membrane lipid bilayer, and are effective in a mouse model of…”
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Genomic transition of enterococci from gut commensals to leading causes of multidrug-resistant hospital infection in the antibiotic era
Published in Current opinion in microbiology (01-02-2013)“…Highlights ► Enterococci are ancient commensals in the GI tracts of hosts ranging from insects to man. ► Enterococci are now leading causes of multidrug…”
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Multidrug-resistant enterococci lack CRISPR-cas
Published in mBio (29-10-2010)“…Clustered, regularly interspaced short palindromic repeats (CRISPR) provide bacteria and archaea with sequence-specific, acquired defense against plasmids and…”
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Tracing the Enterococci from Paleozoic Origins to the Hospital
Published in Cell (18-05-2017)“…We examined the evolutionary history of leading multidrug resistant hospital pathogens, the enterococci, to their origin hundreds of millions of years ago. Our…”
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Structure, function, and biology of the Enterococcus faecalis cytolysin
Published in Toxins (29-04-2013)“…Enterococcus faecalis is a Gram-positive commensal member of the gut microbiota of a wide range of organisms. With the advent of antibiotic therapy, it has…”
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Bacterial Hypoxic Responses Revealed as Critical Determinants of the Host-Pathogen Outcome by TnSeq Analysis of Staphylococcus aureus Invasive Infection
Published in PLoS pathogens (01-12-2015)“…Staphylococcus aureus is capable of infecting nearly every organ in the human body. In order to infiltrate and thrive in such diverse host tissues,…”
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Mechanisms and consequences of gut commensal translocation in chronic diseases
Published in Gut microbes (03-03-2020)“…Humans and other mammalian hosts have evolved mechanisms to control the bacteria colonizing their mucosal barriers to prevent invasion. While the breach of…”
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Native Microbial Colonization of Drosophila melanogaster and Its Use as a Model of Enterococcus faecalis Pathogenesis
Published in Infection and Immunity (01-04-2007)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Identification of a Botulinum Neurotoxin-like Toxin in a Commensal Strain of Enterococcus faecium
Published in Cell host & microbe (14-02-2018)“…Botulinum neurotoxins (BoNTs), produced by various Clostridium strains, are a family of potent bacterial toxins and potential bioterrorism agents. Here we…”
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15
Spatiotemporal variation in hunting in a riverine indigenous community in the Amazon
Published in Biodiversity and conservation (01-03-2023)“…Hunting is a critical source of food security and income for millions of people across the Amazon Basin, but unsustainable hunting is one of the leading causes…”
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Horizontal gene transfer and the genomics of enterococcal antibiotic resistance
Published in Current opinion in microbiology (01-10-2010)“…Enterococci are Gram-positive bacteria that normally colonize gastrointestinal tracts of humans and animals. They are of growing concern because of their…”
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Genetic diversity among Enterococcus faecalis
Published in PloS one (04-07-2007)“…Enterococcus faecalis, a ubiquitous member of mammalian gastrointestinal flora, is a leading cause of nosocomial infections and a growing public health…”
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Staphylococcus aureus from ocular and otolaryngology infections are frequently resistant to clinically important antibiotics and are associated with lineages of community and hospital origins
Published in PloS one (06-12-2018)“…Staphylococcus aureus is an important human pathogen that causes serious antibiotic-resistant infections. Its population structure is marked by the appearance…”
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Genome-wide screen for genes involved in eDNA release during biofilm formation by Staphylococcus aureus
Published in Proceedings of the National Academy of Sciences - PNAS (18-07-2017)“…Staphylococcus aureus is a leading cause of both nosocomial and community-acquired infection. Biofilm formation at the site of infection reduces antimicrobial…”
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Peptidoglycan deacetylation controls type IV secretion and the intracellular survival of the bacterial pathogen Legionella pneumophila
Published in Proceedings of the National Academy of Sciences - PNAS (06-06-2023)“…Peptidoglycan is a critical component of the bacteria cell envelope. Remodeling of the peptidoglycan is required for numerous essential cellular processes and…”
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