Search Results - "Gillis, J Andrew"
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Adult chondrogenesis and spontaneous cartilage repair in the skate, Leucoraja erinacea
Published in eLife (12-05-2020)“…Mammalian articular cartilage is an avascular tissue with poor capacity for spontaneous repair. Here, we show that embryonic development of cartilage in the…”
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Embryonic origin and serial homology of gill arches and paired fins in the skate, Leucoraja erinacea
Published in eLife (17-11-2020)“…Paired fins are a defining feature of the jawed vertebrate body plan, but their evolutionary origin remains unresolved. Gegenbaur proposed that paired fins…”
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3
Gill developmental program in the teleost mandibular arch
Published in eLife (28-06-2022)“…Whereas no known living vertebrate possesses gills derived from the jaw-forming mandibular arch, it has been proposed that the jaw arose through modifications…”
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Resegmentation is an ancestral feature of the gnathostome vertebral skeleton
Published in eLife (24-02-2020)“…The vertebral skeleton is a defining feature of vertebrate animals. However, the mode of vertebral segmentation varies considerably between major lineages. In…”
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5
Structure of the Tribolium castaneum telomerase catalytic subunit TERT
Published in Nature (02-10-2008)“…A common hallmark of human cancers is the overexpression of telomerase, a ribonucleoprotein complex that is responsible for maintaining the length and…”
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hox gene expression predicts tetrapod-like axial regionalization in the skate, Leucoraja erinacea
Published in Proceedings of the National Academy of Sciences - PNAS (21-12-2021)“…The axial skeleton of tetrapods is organized into distinct anteroposterior regions of the vertebral column (cervical, trunk, sacral, and caudal), and…”
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Trunk neural crest origin of dermal denticles in a cartilaginous fish
Published in Proceedings of the National Academy of Sciences - PNAS (12-12-2017)“…Cartilaginous fishes (e.g., sharks and skates) possess a postcranial dermal skeleton consisting of tooth-like “denticles” embedded within their skin. As with…”
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Defining the early stages of intestinal colonisation by whipworms
Published in Nature communications (01-04-2022)“…Whipworms are large metazoan parasites that inhabit multi-intracellular epithelial tunnels in the large intestine of their hosts, causing chronic disease in…”
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A stem-deuterostome origin of the vertebrate pharyngeal transcriptional network
Published in Proceedings of the Royal Society. B, Biological sciences (22-01-2012)“…Hemichordate worms possess ciliated gills on their trunk, and the homology of these structures with the pharyngeal gill slits of chordates has long been a…”
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Embryonic origin of the gnathostome vertebral skeleton
Published in Proceedings of the Royal Society. B, Biological sciences (29-11-2017)“…The vertebral column is a key component of the jawed vertebrate (gnathostome) body plan, but the primitive embryonic origin of this skeleton remains unclear…”
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Ectodermal Wnt signaling, cell fate determination, and polarity of the skate gill arch skeleton
Published in eLife (20-03-2023)“…The gill skeleton of cartilaginous fishes (sharks, skates, rays, and holocephalans) exhibits a striking anterior-posterior polarity, with a series of fine…”
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The evolution and development of vertebrate lateral line electroreceptors
Published in Journal of experimental biology (01-07-2013)“…Electroreception is an ancient vertebrate sense with a fascinating evolutionary history involving multiple losses as well as independent evolution at least…”
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Prognostic heterogeneity and clonal dynamics within distinct subgroups of myelodysplastic syndrome and acute myeloid leukemia with TP53 disruptions
Published in EJHaem (01-11-2023)“…aberrations constitute the highest risk subset of myelodysplastic neoplasms (MDS) and acute myeloid leukemia (AML). The International Consensus Classification…”
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14
A Natural Deletion of the HoxC Cluster in Elasmobranch Fishes
Published in Science (American Association for the Advancement of Science) (16-12-2011)“…Hox proteins are a metazoan-specific family of transcription factors that are required for developmental patterning. The genomic arrangement of Hox genes into…”
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Shared developmental mechanisms pattern the vertebrate gill arch and paired fin skeletons
Published in Proceedings of the National Academy of Sciences - PNAS (07-04-2009)“…Here, we describe the molecular patterning of chondrichthyan branchial rays (gill rays) and reveal profound developmental similarities between gill rays and…”
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Electrosensory ampullary organs are derived from lateral line placodes in cartilaginous fishes
Published in Development (Cambridge) (01-09-2012)“…Ampullary organ electroreceptors excited by weak cathodal electric fields are used for hunting by both cartilaginous and non-teleost bony fishes. Despite…”
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Scales, scutes, and embryonic origins of the vertebrate dermal skeleton
Published in Proceedings of the National Academy of Sciences - PNAS (15-08-2023)Get full text
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Identification of multiple transcription factor genes potentially involved in the development of electrosensory versus mechanosensory lateral line organs
Published in Frontiers in cell and developmental biology (18-03-2024)“…In electroreceptive jawed vertebrates, embryonic lateral line placodes give rise to electrosensory ampullary organs as well as mechanosensory neuromasts…”
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The pseudobranch of jawed vertebrates is a mandibular arch-derived gill
Published in Development (Cambridge) (01-07-2022)“…The pseudobranch is a gill-like epithelial elaboration that sits behind the jaw of most fishes. This structure was classically regarded as a vestige of the…”
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Holocephalan embryos provide evidence for gill arch appendage reduction and opercular evolution in cartilaginous fishes
Published in Proceedings of the National Academy of Sciences - PNAS (25-01-2011)“…Chondrichthyans possess endoskeletal appendages called branchial rays that extend laterally from their hyoid and gill-bearing (branchial) arches. Branchial ray…”
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