Search Results - "Gillies, Mark C."

Loss of Müller's Cells and Photoreceptors in Macular Telangiectasia Type 2 by Powner, Michael B., PhD, Gillies, Mark C., MBBS, PhD, Zhu, Meidong, MBBS, PhD, Vevis, Kristis, MSc (Hons), Hunyor, Alex P., MBBS, FRANZCO, Fruttiger, Marcus, PhD

“…Purpose To correlate postmortem histology from a patient with macular telangiectasia (MacTel) type 2 with previously recorded clinical imaging data. Design…”
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METAANALYSIS OF REAL-WORLD OUTCOMES OF INTRAVITREAL RANIBIZUMAB FOR THE TREATMENT OF NEOVASCULAR AGE-RELATED MACULAR DEGENERATION by Kim, Leah N, Mehta, Hemal, Barthelmes, Daniel, Nguyen, Vuong, Gillies, Mark C

“…To report the efficacy and safety of intravitreal ranibizumab for neovascular age-related macular degeneration (nAMD) in real-world practice. Metaanalysis of…”
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Switching between ranibizumab and aflibercept for the treatment of neovascular age-related macular degeneration by Mantel, Irmela, Gillies, Mark C., Souied, Eric H.

“…The introduction of antivascular endothelial growth factor agents such as ranibizumab and aflibercept has revolutionized the management of neovascular…”
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Diabetic macular edema: new concepts in patho-physiology and treatment by Zhang, Xinyuan, Zeng, Huan, Bao, Shian, Wang, Ningli, Gillies, Mark C

“…Diabetic macular edema (DME), a serious eye complication caused primarily by hyperglycemia, is one of the major causes of blindness. DME, which is…”
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JR5558 mice are a reliable model to investigate subretinal fibrosis by Seyed-Razavi, Yashar, Lee, So-Ra, Fan, Jiawen, Shen, Weiyong, Cornish, Elisa E., Gillies, Mark C.

“…Subretinal fibrosis is a major untreatable cause of poor outcomes in neovascular age-related macular degeneration. Mouse models of subretinal fibrosis all…”
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TWO YEAR OUTCOMES OF "TREAT AND EXTEND" INTRAVITREAL THERAPY USING AFLIBERCEPT PREFERENTIALLY FOR NEOVASCULAR AGE-RELATED MACULAR DEGENERATION by Barthelmes, Daniel, Nguyen, Vuong, Daien, Vincent, Campain, Anna, Walton, Richard, Guymer, Robyn, Morlet, Nigel, Hunyor, Alex P, Essex, Rohan W, Arnold, Jennifer J, Gillies, Mark C

“…To report 24-month outcomes of a treat and extend (T&E) regimen using aflibercept in eyes with neovascular age-related macular degeneration. This was a…”
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Treatment Patterns and Visual Outcomes during the Maintenance Phase of Treat-and-Extend Therapy for Age-Related Macular Degeneration by Essex, Rohan W., MBBS, Nguyen, Vuong, PhD, Walton, Richard, MSc, Arnold, Jennifer J., MBBS (Hons), McAllister, Ian L., MBBS, Guymer, Robyn H., MBBS, PhD, Morlet, Nigel, MBBS, Young, Stephanie, MBBS, Barthelmes, Daniel, MD, PhD, Gillies, Mark C., MBBS, PhD

“…Purpose To present the treatment patterns, disease activity, and visual outcomes of eyes in the maintenance phase of a treat-and-extend regimen for neovascular…”
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Perifoveal Müller Cell Depletion in a Case of Macular Telangiectasia Type 2 by Powner, Michael B., BSc(Hons), Gillies, Mark C., MBBS, PhD, Tretiach, Marina, PhD, Scott, Andrew, MD, MRCOphth, Guymer, Robyn H., MBBS, PhD, Hageman, Gregory S., PhD, Fruttiger, Marcus, PhD

“…Purpose To assess the histopathologic changes in a postmortem sample derived from an eye donor with macular telangiectasia (MacTel) type 2 to gain further…”
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A systematic review of real-world evidence of the management of macular oedema secondary to branch retinal vein occlusion by Ang, Juan Lyn, Ah-Moye, Sarah, Kim, Leah N., Nguyen, Vuong, Hunt, Adrian, Barthelmes, Daniel, Gillies, Mark C., Mehta, Hemal

“…This review assessed the real-world evidence of the management of macular oedema secondary to branch retinal vein occlusion (BRVO). A meta-analysis of 2530…”
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Twelve-Month Outcomes of Ranibizumab vs. Aflibercept for Neovascular Age-Related Macular Degeneration: Data from an Observational Study by Gillies, Mark C., MBBS, PhD, Nguyen, Vuong, PhD, Daien, Vincent, MD, PhD, Arnold, Jennifer J., MBBS (Hons), Morlet, Nigel, MBBS, Barthelmes, Daniel, MD, PhD

“…Purpose To directly compare visual acuity (VA) outcomes with ranibizumab vs. aflibercept for eyes with neovascular age-related macular degeneration (nAMD)…”
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Two-Year Outcomes of “Treat and Extend” Intravitreal Therapy for Neovascular Age-Related Macular Degeneration by Arnold, Jennifer J., MB BS (Hons), Campain, Anna, PhD, Barthelmes, Daniel, MD, PhD, Simpson, Judy M., PhD, CStat, Guymer, Robyn H., MB BS, PhD, Hunyor, Alex P., MB BS, McAllister, Ian L., MB BS, Essex, Rohan W., MB BS, Morlet, Nigel, MB BS, Gillies, Mark C., MB BS, PhD

“…Purpose To report 24-month outcomes of anti-vascular endothelial growth factor (VEGF) therapy for treatment-naïve eyes with neovascular age-related macular…”
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Bevacizumab or Dexamethasone Implants for DME: 2-year Results (The BEVORDEX Study) by Fraser-Bell, Samantha, PhD, FRANZCO, Lim, Lyndell L., DMedSci, FRANZCO, Campain, Anna, PhD, Mehta, Hemal, MA, FRCOphth, Aroney, Christine, MBBS, Bryant, Jaclyn, BAppSci (Orthoptics), Li, Ji, BSc, MBBS, Quin, Godfrey J., PhD, FRANZCO, McAllister, Ian L., FRANZCO, Gillies, Mark C., PhD, FRANZCO

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The Impact of Anti–Vascular Endothelial Growth Factor Treatment on Quality of Life in Neovascular Age-Related Macular Degeneration by Finger, Robert P., PhD, Guymer, Robyn H., PhD, Gillies, Mark C., PhD, Keeffe, Jill E., PhD

“…Purpose To assess the impact of anti–vascular endothelial growth factor (VEGF) treatment in routine medical practice on vision-related quality of life (VRQoL)…”
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Disruption of De Novo Serine Synthesis in Müller Cells Induced Mitochondrial Dysfunction and Aggravated Oxidative Damage by Zhang, Ting, Gillies, Mark C., Madigan, Michele C., Shen, Weiyong, Du, Jianhai, Grünert, Ulrike, Zhou, Fanfan, Yam, Michelle, Zhu, Ling

“…De novo serine synthesis plays important roles in normal mitochondrial function and cellular anti-oxidative capacity. It is reported to be mainly activated in…”
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Optogenetic restoration of high sensitivity vision with bReaChES, a red-shifted channelrhodopsin by Too, Lay Khoon, Shen, Weiyong, Protti, Dario A., Sawatari, Atomu, A. Black, Dylan, Leamey, Catherine A., Y. Huang, Jin, Lee, So-Ra, E. Mathai, Ashish, Lisowski, Leszek, Y. Lin, John, C. Gillies, Mark, Simunovic, Matthew P.

“…The common final pathway to blindness in many forms of retinal degeneration is the death of the light-sensitive primary retinal neurons. However, the normally…”
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Initial response and 12-month outcomes after commencing dexamethasone or vascular endothelial growth factor inhibitors for retinal vein occlusion in the FRB registry by Garay-Aramburu, Gonzaga, Hunt, Adrian, Arruabarrena, Carolina, Mehta, Hemal, Invernizzi, Alessandro, Gabrielle, Pierre-Henry, Guillaumie, Tremeur, Wolff, Benjamin, Gillies, Mark C., Zarranz-Ventura, Javier

“…To compare baseline characteristics, initial response and 12-month efficacy and safety outcomes in eyes with branch and central retinal vein occlusion (BRVO…”
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Projection of Long-Term Visual Acuity Outcomes Based on Initial Treatment Response in Neovascular Age-Related Macular Degeneration by Nguyen, Vuong, Daien, Vincent, Guymer, Robyn, Young, Stephanie, Hunyor, Alex, Fraser-Bell, Samantha, Hunt, Adrian, Gillies, Mark C., Barthelmes, Daniel

“…To explore various methods for assessing the early response to vascular endothelial growth factor (VEGF) inhibitors for neovascular age-related macular…”
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Defining a Minimum Set of Standardized Patient-centered Outcome Measures for Macular Degeneration by Rodrigues, Ian A., MBBS, BSc, FRCOphth, Sprinkhuizen, Sara M., PhD, MSc, Barthelmes, Daniel, MD, PhD, Blumenkranz, Mark, MD, MS, Cheung, Gemmy, FRCOphth, Haller, Julia, MD, Johnston, Robert, FRCOphth, Kim, Ramasamy, DO, DNB, Klaver, Caroline, MD, PhD, McKibbin, Martin, FRCOphth, Ngah, Nor Fariza, MBBS, Pershing, Suzann, MD, MS, Shankar, Dato, Tamura, Hiroshi, MD, PhD, MSc, Tufail, Adnan, MD, FRCOphth, Weng, Christina Y., MD, MBA, Westborg, Inger, MD, Yelf, Catherine, Yoshimura, Nagahisa, MD, PhD, Gillies, Mark C., MBBS, PhD

“…Purpose To define a minimum set of outcome measures for tracking, comparing, and improving macular degeneration care. Design Recommendations from working-group…”
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Human macular Müller cells rely more on serine biosynthesis to combat oxidative stress than those from the periphery by Zhang, Ting, Zhu, Ling, Madigan, Michele C, Liu, Wei, Shen, Weiyong, Cherepanoff, Svetlana, Zhou, Fanfan, Zeng, Shaoxue, Du, Jianhai, Gillies, Mark C

“…The human macula is more susceptible than the peripheral retina to developing blinding conditions such as age-related macular degeneration, diabetic…”
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Effects of VEGF inhibitors on human retinal pigment epithelium under high glucose and hypoxia by Bahrami, Bobak, Shen, Weiyong, Zhu, Ling, Zhang, Ting, Chang, Andrew, Gillies, Mark C.

“…Background Retinal pigment epithelium (RPE) is known to secrete factors important for retinal homeostasis. How this secretome changes in diabetic eyes treated…”
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