Search Results - "Gillett, Frank"
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A ubiquitin ligase mediates target-directed microRNA decay independently of tailing and trimming
Published in Science (American Association for the Advancement of Science) (18-12-2020)“…MicroRNAs (miRNAs) act in concert with Argonaute (AGO) proteins to repress target messenger RNAs. After AGO loading, miRNAs generally exhibit slow turnover. An…”
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Journal Article -
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PUMILIO hyperactivity drives premature aging of Norad -deficient mice
Published in eLife (08-02-2019)“…Although numerous long noncoding RNAs (lncRNAs) have been identified, our understanding of their roles in mammalian physiology remains limited. Here, we…”
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Journal Article