Search Results - "Gillespie, Anna K"

Hippocampal replay reflects specific past experiences rather than a plan for subsequent choice by Gillespie, Anna K., Astudillo Maya, Daniela A., Denovellis, Eric L., Liu, Daniel F., Kastner, David B., Coulter, Michael E., Roumis, Demetris K., Eden, Uri T., Frank, Loren M.

“…Executing memory-guided behavior requires storage of information about experience and later recall of that information to inform choices. Awake hippocampal…”
Get full text

Early Hippocampal Sharp-Wave Ripple Deficits Predict Later Learning and Memory Impairments in an Alzheimer’s Disease Mouse Model by Jones, Emily A., Gillespie, Anna K., Yoon, Seo Yeon, Frank, Loren M., Huang, Yadong

“…Alzheimer’s disease (AD) is characterized by progressive memory loss, and there is a pressing need to identify early pathophysiological alterations that…”
Get full text

Hippocampal replay of experience at real-world speeds by Denovellis, Eric L, Gillespie, Anna K, Coulter, Michael E, Sosa, Marielena, Chung, Jason E, Eden, Uri T, Frank, Loren M

“…Representations related to past experiences play a critical role in memory and decision-making processes. The rat hippocampus expresses these types of…”
Get full text

Neurofeedback training can modulate task-relevant memory replay rate in rats by Gillespie, Anna K, Astudillo Maya, Daniela, Denovellis, Eric L, Desse, Sachi, Frank, Loren M

“…Hippocampal replay - the time-compressed, sequential reactivation of ensembles of neurons related to past experience - is a key neural mechanism of memory…”
Get full text

Hilar GABAergic interneuron activity controls spatial learning and memory retrieval by Andrews-Zwilling, Yaisa, Gillespie, Anna K, Kravitz, Alexxai V, Nelson, Alexandra B, Devidze, Nino, Lo, Iris, Yoon, Seo Yeon, Bien-Ly, Nga, Ring, Karen, Zwilling, Daniel, Potter, Gregory B, Rubenstein, John L R, Kreitzer, Anatol C, Huang, Yadong

“…Although extensive research has demonstrated the importance of excitatory granule neurons in the dentate gyrus of the hippocampus in normal learning and memory…”
Get full text

Cross-Species Functional Analysis of Cancer-Associated Fibroblasts Identifies a Critical Role for CLCF1 and IL-6 in Non-Small Cell Lung Cancer In Vivo by VICENT, Silvestre, SAYLES, Leanne C, SHRAGER, Joseph, HOANG, Chuong D, PLEVRITIS, Sylvia, BUTTE, Atul J, ALEJANDRO SWEET-CORDERO, E, VAKA, Dedeepya, KHATRI, Purvesh, GEVAERT, Olivier, CHEN, Ron, ZHENG, Yanyan, GILLESPIE, Anna K, CLARKE, Nicole, YUE XU

“…Cancer-associated fibroblasts (CAF) have been reported to support tumor progression by a variety of mechanisms. However, their role in the progression of…”
Get full text

Neural Activity Patterns Underlying Spatial Coding in the Hippocampus by Sosa, Marielena, Gillespie, Anna K, Frank, Loren M

“…The hippocampus is well known as a central site for memory processing-critical for storing and later retrieving the experiences events of daily life so they…”
Get more information

Apolipoprotein E4 Causes Age-Dependent Disruption of Slow Gamma Oscillations during Hippocampal Sharp-Wave Ripples by Gillespie, Anna K., Jones, Emily A., Lin, Yuan-Hung, Karlsson, Mattias P., Kay, Kenneth, Yoon, Seo Yeon, Tong, Leslie M., Nova, Philip, Carr, Jessie S., Frank, Loren M., Huang, Yadong

“…Apolipoprotein (apo) E4 is the major genetic risk factor for Alzheimer’s disease (AD), but the mechanism by which it causes cognitive decline is unclear. In…”
Get full text

Two new marsupial lion taxa (Marsupialia, Thylacoleonidae) from the early and Middle Miocene of Australia by Gillespie, Anna K.

“…Five species of marsupial lions (Thylacoleonidae) have been documented from the Oligo-Miocene freshwater limestone deposits of the Riversleigh World Heritage…”
Get full text

Reducing human apolipoprotein E levels attenuates age-dependent Aβ accumulation in mutant human amyloid precursor protein transgenic mice by Bien-Ly, Nga, Gillespie, Anna K, Walker, David, Yoon, Seo Yeon, Huang, Yadong

“…Apolipoprotein E4 (apoE4) plays a major role in the pathogenesis of Alzheimer's disease. Brain amyloid-β (Aβ) accumulation depends on age and apoE isoforms…”
Get full text

Apolipoprotein E4 produced in GABAergic interneurons causes learning and memory deficits in mice by Knoferle, Johanna, Yoon, Seo Yeon, Walker, David, Leung, Laura, Gillespie, Anna K, Tong, Leslie M, Bien-Ly, Nga, Huang, Yadong

“…Apolipoprotein (apo) E4 is expressed in many types of brain cells, is associated with age-dependent decline of learning and memory in humans, and is the major…”
Get full text

Memory Alone Does Not Account for the Way Rats Learn a Simple Spatial Alternation Task by Kastner, David B, Gillespie, Anna K, Dayan, Peter, Frank, Loren M

“…Animal behavior provides context for understanding disease models and physiology. However, that behavior is often characterized subjectively, creating…”
Get full text

Dynamic synchronization between hippocampal representations and stepping by Joshi, Abhilasha, Denovellis, Eric L., Mankili, Abhijith, Meneksedag, Yagiz, Davidson, Thomas J., Gillespie, Anna K., Guidera, Jennifer A., Roumis, Demetris, Frank, Loren M.

“…The hippocampus is a mammalian brain structure that expresses spatial representations 1 and is crucial for navigation 2 , 3 . Navigation, in turn, intricately…”
Get full text

Efficient Decoding of Multi-Dimensional Signals From Population Spiking Activity Using a Gaussian Mixture Particle Filter by Yousefi, Ali, Gillespie, Anna K., Guidera, Jennifer A., Karlsson, Mattias, Frank, Loren M., Eden, Uri T.

“…New recording technologies and the potential for closed-loop experiments have led to an increasing demand for computationally efficient and accurate algorithms…”
Get full text

Inhibitory interneuron progenitor transplantation restores normal learning and memory in ApoE4 knock-in mice without or with Aβ accumulation by Tong, Leslie M, Djukic, Biljana, Arnold, Christine, Gillespie, Anna K, Yoon, Seo Yeon, Wang, Max M, Zhang, Olivia, Knoferle, Johanna, Rubenstein, John L R, Alvarez-Buylla, Arturo, Huang, Yadong

“…Excitatory and inhibitory balance of neuronal network activity is essential for normal brain function and may be of particular importance to memory…”
Get full text

Lekaneleo, a New Genus of Marsupial Lion (Marsupialia, Thylacoleonidae) from the Oligocene–Miocene of Australia, and the Craniodental Morphology of L. roskellyae, comb. nov by Gillespie, Anna K, Archer, Michael, Hand, Suzanne J

“…The domestic cat-sized marsupial lion Priscileo roskellyae (Thylacoleonidae) from the Oligocene–Miocene of Australia was originally allocated to the genus…”
Get full text

Dentate gyrus and CA3 GABAergic interneurons bidirectionally modulate signatures of internal and external drive to CA1 by Aery Jones, Emily A., Rao, Antara, Zilberter, Misha, Djukic, Biljana, Bant, Jason S., Gillespie, Anna K., Koutsodendris, Nicole, Nelson, Maxine, Yoon, Seo Yeon, Huang, Ky, Yuan, Heidi, Gill, Theodore M., Huang, Yadong, Frank, Loren M.

“…Specific classes of GABAergic neurons play specific roles in regulating information processing in the brain. In the hippocampus, two major classes,…”
Get full text

A new Oligo-Miocene marsupial lion from Australia and revision of the family Thylacoleonidae by Gillespie, Anna K., Archer, Michael, Hand, Suzanne J.

“…Wakaleo schouteni sp. nov., a dog-sized marsupial lion (Thylacoleonidae), is described from late Oligocene to early Miocene sediments of the Riversleigh World…”
Get full text

Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models by Vicent, Silvestre, Chen, Ron, Sayles, Leanne C, Lin, Chenwei, Walker, Randal G, Gillespie, Anna K, Subramanian, Aravind, Hinkle, Gregory, Yang, Xiaoping, Saif, Sakina, Root, David E, Huff, Vicki, Hahn, William C, Sweet-Cordero, E Alejandro

“…KRAS is one of the most frequently mutated human oncogenes. In some settings, oncogenic KRAS can trigger cellular senescence, whereas in others it produces…”
Get full text

Approaching Alzheimer's disease from a network level by Gillespie, Anna K, Jones, Emily A, Huang, Yadong

Get full text