Search Results - "Gilles, M."

Metformin induces apoptosis through AMPK-dependent inhibition of UPR signaling in ALL lymphoblasts by Leclerc, Gilles M, Leclerc, Guy J, Kuznetsov, Jeffim N, DeSalvo, Joanna, Barredo, Julio C

“…The outcome of patients with resistant phenotypes of acute lymphoblastic leukemia (ALL) or those who relapse remains poor. We investigated the mechanism of…”
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Polarization domain walls in optical fibres as topological bits for data transmission by Gilles, M., Bony, P.-Y., Garnier, J., Picozzi, A., Guasoni, M., Fatome, J.

“…Domain walls are topological defects that occur at symmetry-breaking phase transitions. Although domain walls have been intensively studied in ferromagnetic…”
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Bioluminescence of Vibrio fischeri: bacteria respond quickly and sensitively to pulsed microwave electric (but not magnetic) fields by Williams, Catrin F, Geroni, Gilles M, Lloyd, David, Choi, Heungjae, Clark, Nicholas, Pirog, Antoine, Lees, Jonathan, Porch, Adrian

“…Biological systems with intrinsic luminescent properties serve as powerful and noninvasive bioreporters for real-time and label-free monitoring of cell…”
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AMPK and Akt determine apoptotic cell death following perturbations of one-carbon metabolism by regulating ER stress in acute lymphoblastic leukemia by Kuznetsov, Jeffim N, Leclerc, Guy J, Leclerc, Gilles M, Barredo, Julio C

“…AICAr is a cell-permeable nucleotide that has been used in vivo and in vitro to activate AMPK. Our previous findings have shown that AICAr as a single agent…”
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Heterogeneous nucleation of ice on anthropogenic organic particles collected in Mexico City by Knopf, D. A., Wang, B., Laskin, A., Moffet, R. C., Gilles, M. K.

“…This study reports on heterogeneous ice nucleation activity of predominantly organic (or coated with organic material) anthropogenic particles sampled within…”
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Oriented Morphology and Anisotropic Transport in Uniaxially Stretched Perfluorosulfonate Ionomer Membranes by Park, Jong Keun, Li, Jing, Divoux, Gilles M, Madsen, Louis A, Moore, Robert B

“…Relations between morphology and transport sensitively govern proton conductivity in perfluorsulfonate ionomers (PFSIs) and thus determine useful properties of…”
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Microspectroscopic imaging and characterization of individually identified ice nucleating particles from a case field study by Knopf, D. A., Alpert, P. A., Wang, B., O'Brien, R. E., Kelly, S. T., Laskin, A., Gilles, M. K., Moffet, R. C.

“…The effect of anthropogenic and biogenic organic particles on atmospheric glaciation processes is poorly understood. We use an optical microscopy setup to…”
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Intrinsic movement variability at work. How long is the path from motor control to design engineering? by Gaudez, C., Gilles, M.A., Savin, J.

“…For several years, increasing numbers of studies have highlighted the existence of movement variability. Before that, it was neglected in movement analysis and…”
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Glass Transition Temperature of Perfluorosulfonic Acid Ionomers by Osborn, Shawn J, Hassan, Mohammad K, Divoux, Gilles M, Rhoades, David W, Mauritz, Kenneth A, Moore, Robert B

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Ergonomic assessment of the surgeon's physical workload during standard and robotic assisted laparoscopic procedures by Hubert, N, Gilles, M, Desbrosses, K, Meyer, JP, Felblinger, J, Hubert, J

“…Background Standard laparoscopy is responsible for musculoskeletal problems because of surgeons anti‐ergonomic positions. Robot‐assisted laparoscopy seems to…”
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Evidence of movement variability patterns during a repetitive pointing task until exhaustion by Savin, J., Gaudez, C., Gilles, M.A., Padois, V., Bidaud, P.

“…Human movement is characterized by its variability: the same task is never performed twice in exactly the same way. This variability is believed to play a…”
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Inhibition of Akt potentiates 2-DG-induced apoptosis via downregulation of UPR in acute lymphoblastic leukemia by DeSalvo, Joanna, Kuznetsov, Jeffim N, Du, Jianfeng, Leclerc, Gilles M, Leclerc, Guy J, Lampidis, Theodore J, Barredo, Julio C

“…The ability to pair the regulation of metabolism and cellular energetics with oncogenes and tumor suppressor genes provides cancer cells with a growth and…”
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Immunotherapeutic approach to reduce senescent cells and alleviate senescence‐associated secretory phenotype in mice by Shrestha, Niraj, Chaturvedi, Pallavi, Zhu, Xiaoyun, Dee, Michael J., George, Varghese, Janney, Christopher, Egan, Jack O., Liu, Bai, Foster, Mark, Marsala, Lynne, Wong, Pamela, Cubitt, Celia C., Foltz, Jennifer A., Tran, Jennifer, Schappe, Timothy, Hsiao, Karin, Leclerc, Gilles M., You, Lijing, Echeverri, Christian, Spanoudis, Catherine, Carvalho, Ana, Kanakaraj, Leah, Gilkes, Crystal, Encalada, Nicole, Kong, Lin, Wang, Meng, Fang, Byron, Wang, Zheng, Jiao, Jin‐an, Muniz, Gabriela J., Jeng, Emily K., Valdivieso, Nicole, Li, Liying, Deth, Richard, Berrien‐Elliott, Melissa M., Fehniger, Todd A., Rhode, Peter R., Wong, Hing C.

“…Accumulation of senescent cells (SNCs) with a senescence‐associated secretory phenotype (SASP) has been implicated as a major source of chronic sterile…”
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A “Prime and Expand” strategy using the multifunctional fusion proteins to generate memory-like NK cells for cell therapy by Shrestha, Niraj, Dee, Michael J., Chaturvedi, Pallavi, Leclerc, Gilles M., Mathyer, Mary, Dufour, Celeste, Arthur, Laura, Becker-Hapak, Michelle, Foster, Mark, McClain, Ethan, Pena, Natalia Valderrama, Kage, Karen, Zhu, Xiaoyun, George, Varghese, Liu, Bai, Egan, Jack, Echeverri, Christian, Wang, Meng, You, Lijing, Kong, Lin, Li, Liying, Berrien-Elliott, Melissa M., Cooper, Matthew L., Fehniger, Todd A., Rhode, Peter R., Wong, Hing C.

“…Adoptive cellular therapy (ACT) using memory-like (ML) natural killer (NK) cells, generated through overnight ex vivo activation with IL-12, IL-15, and IL-18,…”
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A phase I window, dose escalating and safety trial of metformin in combination with induction chemotherapy in relapsed refractory acute lymphoblastic leukemia: Metformin with induction chemotherapy of vincristine, dexamethasone, PEG‐asparaginase, and doxorubicin by Trucco, Matteo, Barredo, Julio C., Goldberg, John, Leclerc, Gilles M., Hale, Gregory A., Gill, Jonathan, Setty, Bhuvana, Smith, Tiffany, Lush, Richard, Lee, Jae K., Reed, Damon R.

“…Background Acute lymphoblastic leukemia (ALL) remains a major cause of death in children. AMP‐activated protein kinase (AMPK) affects the unfolded protein…”
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All-optical sampling and magnification based on XPM-induced focusing by Nuño, J, Gilles, M, Guasoni, M, Finot, C, Fatome, J

“…We theoretically and experimentally investigate the design of an all-optical magnification and sampling function free from any active gain medium or additional…”
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A Fusion Protein Complex that Combines IL-12, IL-15, and IL-18 Signaling to Induce Memory-Like NK Cells for Cancer Immunotherapy by Becker-Hapak, Michelle K, Shrestha, Niraj, McClain, Ethan, Dee, Michael J, Chaturvedi, Pallavi, Leclerc, Gilles M, Marsala, Lynne I, Foster, Mark, Schappe, Timothy, Tran, Jennifer, Desai, Sweta, Neal, Carly C, Pence, Patrick, Wong, Pamela, Wagner, Julia A, Russler-Germain, David A, Zhu, Xiaoyun, Spanoudis, Catherine M, Gallo, Victor L, Echeverri, Christian A, Ramirez, Laritza L, You, Lijing, Egan, Jack O, Rhode, Peter R, Jiao, Jin-An, Muniz, Gabriela J, Jeng, Emily K, Prendes, Caitlin A, Sullivan, Ryan P, Berrien-Elliott, Melissa M, Wong, Hing C, Fehniger, Todd A

“…Natural killer (NK) cells are a promising cellular therapy for cancer, with challenges in the field including persistence, functional activity, and tumor…”
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Phase I study of onapristone, a type I antiprogestin, in female patients with previously treated recurrent or metastatic progesterone receptor-expressing cancers by Cottu, Paul H, Bonneterre, Jacques, Varga, Andrea, Campone, Mario, Leary, Alexandra, Floquet, Anne, Berton-Rigaud, Dominique, Sablin, Marie-Paule, Lesoin, Anne, Rezai, Keyvan, Lokiec, François M, Lhomme, Catherine, Bosq, Jacques, Bexon, Alice S, Gilles, Erard M, Proniuk, Stefan, Dieras, Veronique, Jackson, David M, Zukiwski, Alexander, Italiano, Antoine

“…Onapristone is a type I progesterone receptor (PR) antagonist, which prevents PR- mediated DNA transcription. Onapristone is active in multiple preclinical…”
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Spectro-microscopic measurements of carbonaceous aerosol aging in Central California by Moffet, R. C, Rödel, T. C, Kelly, S. T, Yu, X. Y, Carroll, G. T, Fast, J, Zaveri, R. A, Laskin, A, Gilles, M. K

“…Carbonaceous aerosols are responsible for large uncertainties in climate models, degraded visibility, and adverse health effects. The Carbonaceous Aerosols and…”
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Prenatal maternal stress is associated with lower cortisol and cortisone levels in the first morning urine of 45-month-old children by Send, T.S., Bardtke, S., Gilles, M., Wolf, I.A.C., Sütterlin, M.W., Wudy, S.A., Wang, R., Laucht, M., Witt, S.H., Rietschel, M., Streit, F., Deuschle, M.

“…•Prospective study on prenatal stress and nocturnal HPA axis activity.•Assessment of cortisol and cortisone in the first morning urine of 45-month-old…”
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