A Comparison of Clinical and Radiographic Signs of Nontuberculous Mycobacterial Pulmonary Disease, Destructive Drug-Resistant Pulmonary Tuberculosis and a Combination of Nontuberculous Mycobacterium Pulmonary Disease and Pulmonary Tuberculosis

A Comparison of Clinical and Radiographic Signs of Nontuberculous Mycobacterial Pulmonary Disease, Destructive Drug-Resistant Pulmonary Tuberculosis and a Combination of Nontuberculous Mycobacterium Pulmonary Disease and Pulmonary Tuberculosis

A misdiagnosis of isolated pulmonary tuberculosis (pTB) is highly likely when a patient has nontuberculous mycobacterial pulmonary disease (NTMPD) or a combination of nontuberculous mycobacterium pulmonary disease and pulmonary tuberculosis. Frequently, bacterial excretion is absent or only Mycobact...

Full description

Saved in:
Bibliographic Details
Published in:Pathogens (Basel) Vol. 12; no. 7; p. 887
Main Authors: Giller, Dmitrii, Scherbakova, Galina, Enilenis, Inga, Martel, Ivan, Kesaev, Oleg, Koroev, Vadim, Popova, Anna, Ilyukhin, Alexandr, Basangova, Valeria, Smerdin, Sergey, Mayusupov, Shokirjon, Saenko, Sergey, Frolova, Olga, Vinarskaya, Veronika, Severova, Lyudmila
Format: Journal Article
Language:English
Published: Switzerland MDPI AG 29-06-2023
MDPI
Subjects:
Antibiotics
Bacteria
Binomial distribution
Bronchiectasis
Care and treatment
clinical signs of NTMPD
Diagnosis
Disease
Drug resistance
Evaluation
Hemoptysis
Hemorrhage
Hospitals
Localization
Lung diseases
Medical tests
nontuberculous mycobacterial pulmonary disease
NTMPD diagnostic imaging
Patients
Pulmonary tuberculosis
Signs and symptoms
Sputum
Thoracic surgery
Tuberculosis
Russia
pulmonary tuberculosis
NTMPD diagnostic imaging
clinical signs of NTMPD
nontuberculous mycobacterial pulmonary disease
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A misdiagnosis of isolated pulmonary tuberculosis (pTB) is highly likely when a patient has nontuberculous mycobacterial pulmonary disease (NTMPD) or a combination of nontuberculous mycobacterium pulmonary disease and pulmonary tuberculosis. Frequently, bacterial excretion is absent or only Mycobacteria tuberculosis (MBT) is found. This often results in an incorrect diagnosis and subsequent misinformed treatment regimes. In order to determine possible clinical and radiographic differences between patients with NTMPD (Group 1), destructive drug-resistant pulmonary tuberculosis (Group 3) and a combination of NTMPD and pTB (Group 2) we compare clinical and radiographic signs for these three patient groups. When comparing with Group 3 (2.5%), Groups 1 (25%) and 2 (17.4%) have a substantially higher incidence of pulmonary haemorrhages. Thus, upon clinically observing the combination of pTB and NTMPD, there are no pathognomonic clinical and radiographic detected symptoms. However, the presence of an indolent course, hemoptysis and bronchiectasis in the presence of acid-fast bacteria (or identified MBT) in the sputum makes it possible to suspect not simple pTB, but a combination of pTB and NTMPD. To clarify this necessitated in-depth bacteriological examination.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:2076-0817
2076-0817
DOI:10.3390/pathogens12070887