Search Results - "Gillen, Matthew"

Genomic and Genetic Characterization of Cholangiocarcinoma Identifies Therapeutic Targets for Tyrosine Kinase Inhibitors by Andersen, Jesper B, Spee, Bart, Blechacz, Boris R, Avital, Itzhak, Komuta, Mina, Barbour, Andrew, Conner, Elizabeth A, Gillen, Matthew C, Roskams, Tania, Roberts, Lewis R, Factor, Valentina M, Thorgeirsson, Snorri S

“…Background & Aims Cholangiocarcinoma is a heterogeneous disease with a poor outcome that accounts for 5%−10% of primary liver cancers. We characterized its…”
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Does enteral nutrition during therapeutic hypothermia increase the risk for necrotizing enterocolitis? by Gillen, Matthew C., Patel, Ravi M.

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Sequential transcriptome analysis of human liver cancer indicates late stage acquisition of malignant traits by Marquardt, Jens U, Seo, Daekwan, Andersen, Jesper B, Gillen, Matthew C, Kim, Myoung Soo, Conner, Elizabeth A, Galle, Peter R, Factor, Valentina M, Park, Young Nyun, Thorgeirsson, Snorri S

“…Background & Aims Human hepatocarcinogenesis is as a multi-step process starting from dysplastic lesions to early carcinomas (eHCC) that ultimately progress to…”
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Epigenetic reprogramming modulates malignant properties of human liver cancer by Raggi, Chiara, Factor, Valentina M., Seo, Daekwan, Holczbauer, Agnes, Gillen, Matthew C., Marquardt, Jens U., Andersen, Jesper B., Durkin, Marian, Thorgeirsson, Snorri S.

“…Reversal of DNA hypermethylation and associated gene silencing is an emerging cancer therapy approach. Here we addressed the impact of epigenetic alterations…”
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PI3K signaling specifies proximal-distal fate by driving a developmental gene regulatory network in SOX9+ mouse lung progenitors by Khattar, Divya, Fernandes, Sharlene, Snowball, John, Guo, Minzhe, Gillen, Matthew C, Jain, Suchi Singh, Sinner, Debora, Zacharias, William, Swarr, Daniel T

“…The tips of the developing respiratory buds are home to important progenitor cells marked by the expression of SOX9 and ID2. Early in embryonic development…”
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KRT Designed for Infants: A Game Changer by Govindan, Sukanya, Gillen, Matthew C, Reidy, Kimberly J, Nada, Arwa, Askenazi, David J, Raina, Rupesh

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Loss of c-Met accelerates development of liver fibrosis in response to CCl4 exposure through deregulation of multiple molecular pathways by Marquardt, Jens U., Seo, Daekwan, Gómez-Quiroz, Luis E., Uchida, Koichi, Gillen, Matthew C., Kitade, Mitsuteru, Kaposi-Novak, Pal, Conner, Elizabeth A., Factor, Valentina M., Thorgeirsson, Snorri S.

“…HGF/c-Met signaling plays a pivotal role in hepatocyte survival and tissue remodeling during liver regeneration. HGF treatment accelerates resolution of…”
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Human hepatic cancer stem cells are characterized by common stemness traits and diverse oncogenic pathways by Marquardt, Jens U., Raggi, Chiara, Andersen, Jesper B., Seo, Daekwan, Avital, Itzhak, Geller, David, Lee, Yun‐Han, Kitade, Mitsuteru, Holczbauer, Agnes, Gillen, Matthew C., Conner, Elizabeth A., Factor, Valentina M., Thorgeirsson, Snorri S.

“…Epigenetic mechanisms play critical roles in stem cell biology by maintaining pluripotency of stem cells and promoting differentiation of more mature…”
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Dynamic and single cell characterization of a CRISPR-interference toolset in Pseudomonas putida KT2440 for β-ketoadipate production from p-coumarate by Fenster, Jacob A., Werner, Allison Z., Tay, Jian Wei, Gillen, Matthew, Schirokauer, Leo, Hill, Nicholas C., Watson, Audrey, Ramirez, Kelsey J., Johnson, Christopher W., Beckham, Gregg T., Cameron, Jeffrey C., Eckert, Carrie A.

“…Pseudomonas putida KT2440 is a well-studied bacterium for the conversion of lignin-derived aromatic compounds to bioproducts. The development of advanced…”
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Inborn errors of metabolism in neonates and pediatrics on varying dialysis modalities: a systematic review and meta-analysis by Raina, Manan, Doshi, Kush, Myneni, Archana, Tibrewal, Abhishek, Gillen, Matthew, Hu, Jieji, Bunchman, Timothy E.

“…Abstract Background Some inborn errors of metabolism (IEMs) resulting in aberrations to blood leucine and ammonia levels are commonly treated with kidney…”
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Correcting Smad1/5/8, mTOR, and VEGFR2 treats pathology in hereditary hemorrhagic telangiectasia models by Ruiz, Santiago, Zhao, Haitian, Chandakkar, Pallavi, Papoin, Julien, Choi, Hyunwoo, Nomura-Kitabayashi, Aya, Patel, Radhika, Gillen, Matthew, Diao, Li, Chatterjee, Prodyot K, He, Mingzhu, Al-Abed, Yousef, Wang, Ping, Metz, Christine N, Oh, S Paul, Blanc, Lionel, Campagne, Fabien, Marambaud, Philippe

“…Hereditary hemorrhagic telangiectasia (HHT), a genetic bleeding disorder leading to systemic arteriovenous malformations (AVMs), is caused by loss-of-function…”
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Quality Improvement to Reduce High-Flow Nasal Cannula Overuse in Children With Bronchiolitis by Treasure, Jennifer D, Lipshaw, Matthew J, Dean, Preston, Paff, Zachary, Arnsperger, Anita, Meyer, Justin, Gillen, Matthew, Segev, Natalie, Woeste, Laura, Mullaney, Randi, O'Neill, William, Fallon, Anne, Gildner, Candace, Brady, Patrick W, Statile, Angela M

“…High-flow nasal cannula oxygen therapy (HFNC) is increasingly used to treat bronchiolitis. However, HFNC has not reduced time on supplemental oxygen, length of…”
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ADVANCE: a biomedical informatics approach to investigate acute kidney injury in infants by Rumpel, Jennifer A, Perazzo, Sofia, Bona, Jonathan, South, Andrew M, Harer, Matthew W, Liu, Daniel, Starr, Michelle C, Khattab, Mona, Han, Rachel, Slagle, Cara, Ciccia, Eileen, Najaf, Tasnim, Gillen, Matthew, Harsono, Mimily, Nada, Arwa, Dwarakanath, Kiran, Gogcu, Semsa, Mohamed, Tahagod, Stoops, Christine, Bonachea, Elizabeth, Revenis, Mary, Roberts, Jessica, Lenzini, Jr, Robert Michael, Debuyserie, Anne, Joseph, Catherine, Murthy, Karna, Ray, Patricio, Schootman, Mario, Nagel, Corey

“…Acute kidney injury (AKI) occurs in up to half of infants admitted to the neonatal intensive care unit (NICU) and is associated with increased risks of death…”
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Loss of c-Met signaling sensitizes hepatocytes to lipotoxicity and induces cholestatic liver damage by aggravating oxidative stress by Gomez-Quiroz, Luis E, Seo, Daekwan, Lee, Yun-Han, Kitade, Mitsuteru, Gaiser, Timo, Gillen, Matthew, Lee, Seung-Bum, Gutierrez-Ruiz, Ma Concepcion, Conner, Elizabeth A, Factor, Valentina M, Thorgeirsson, Snorri S, Marquardt, Jens U

“…Abstract Recent studies confirmed a critical importance of c-Met signaling for liver regeneration by modulating redox balance. Here we used liver-specific…”
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Kidney Health Monitoring in Neonatal Intensive Care Unit Graduates: A Modified Delphi Consensus Statement by Starr, Michelle C, Harer, Matthew W, Steflik, Heidi J, Gorga, Stephen, Ambalavanan, Namasivayam, Beck, Tara M, Chaudhry, Paulomi M, Chmielewski, Jennifer L, Defreitas, Marissa J, Fuhrman, Dana Y, Hanna, Mina, Joseph, Catherine, Kwiatkowski, David M, Krawczeski, Catherine D, Liberio, Brianna M, Menon, Shina, Mohamed, Tahagod H, Rumpel, Jennifer A, Sanderson, Keia R, Schuh, Meredith P, Segar, Jeffrey L, Slagle, Cara L, Soranno, Danielle E, Vuong, Kim T, Charlton, Jennifer R, Gist, Katja M, Askenazi, David J, Selewski, David T

“…Kidney disease is common in infants admitted to the neonatal intensive care unit (NICU). Despite the risk of chronic kidney disease (CKD) in infants discharged…”
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Abstract 4927: Translational genomics analyses of cholangiocarcinoma identify patients who may respond to tyrosine kinase inhibitors by Andersen, Jesper Boeje, Gillen, Matthew, Conner, Elisabeth A., Factor, Valentina M., Thorgeirsson, Snorri S.

“…Abstract Background & Aims: Cholangiocarcinoma (CCA) is a heterogeneous disease with poor outcome that accounts for 5-10% of primary liver cancers. We recently…”
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Data Ferrying to the Tactical Edge: A Field Experiment in Exchanging Mission Plans and Intelligence in Austere Environments by Usbeck, Kyle, Gillen, Matthew, Loyall, Joseph, Gronosky, Andrew, Sterling, Joshua, Kohler, Ralph, Newkirk, Richard, Canestrare, David

“…The effectiveness of ground-based, wireless tactical data networks is often constrained by limitations such as communication range and line-of-sight. SATCOM is…”
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Dynamic policy-driven quality of service in service-oriented information management systems by Loyall, Joseph P., Gillen, Matthew, Paulos, Aaron, Bunch, Larry, Carvalho, Marco, Edmondson, James, Schmidt, Douglas C., Martignoni III, Andrew, Sinclair, Asher

“…SUMMARY SOA middleware has emerged as a powerful and popular distributed computing paradigm because of its high‐level ions for composing systems and…”
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Dynamic Quality of Service Management for Multicast Tactical Communications by Gillen, M, Loyall, J P, Sterling, J

“…Wireless networking is moving toward the adoption of IP protocols and away from the multitude of special-purpose tactical radios traditionally in the hands of…”
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Beyond line-of-sight information dissemination for Force Protection by Gillen, M., Loyall, J., Usbeck, K., Hanlon, K., Scally, A., Sterling, J., Newkirk, R., Kohler, R.

“…Force protection capabilities have emerged as necessary for operations such as Village Stability Operations and Forward Operating Base security. Current Force…”
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