Search Results - "Gillen, Daniel L"

The ANTsX ecosystem for quantitative biological and medical imaging by Tustison, Nicholas J., Cook, Philip A., Holbrook, Andrew J., Johnson, Hans J., Muschelli, John, Devenyi, Gabriel A., Duda, Jeffrey T., Das, Sandhitsu R., Cullen, Nicholas C., Gillen, Daniel L., Yassa, Michael A., Stone, James R., Gee, James C., Avants, Brian B.

“…The Advanced Normalizations Tools ecosystem, known as ANTsX, consists of multiple open-source software libraries which house top-performing algorithms used…”
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Airway inflammation and oxidative potential of air pollutant particles in a pediatric asthma panel by Delfino, Ralph J, Staimer, Norbert, Tjoa, Thomas, Gillen, Daniel L, Schauer, James J, Shafer, Martin M

“…Airborne particulate matter (PM) components from fossil fuel combustion can induce oxidative stress initiated by reactive oxygen species (ROS). Reported…”
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Hippocampal gene expression patterns linked to late-life physical activity oppose age and AD-related transcriptional decline by Berchtold, Nicole C., Prieto, G. Aleph, Phelan, Michael, Gillen, Daniel L., Baldi, Pierre, Bennett, David A., Buchman, Aron S., Cotman, Carl W.

“…Exercise has emerged as a powerful variable that can improve cognitive function and delay age-associated cognitive decline and Alzheimer's disease (AD);…”
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Air Pollution Exposures and Circulating Biomarkers of Effect in a Susceptible Population: Clues to Potential Causal Component Mixtures and Mechanisms by Delfino, Ralph J., Staimer, Norbert, Tjoa, Thomas, Gillen, Daniel L., Polidori, Andrea, Arhami, Mohammad, Kleinman, Micheal T., Vaziri, Nosratola D., Longhurst, John, Sioutas, Constantinos

“…Background: Mechanisms involving oxidative stress and inflammation have been proposed to explain associations of ambient air pollution with cardiovascular…”
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Estimating attrition in mild-to-moderate Alzheimer's disease and mild cognitive impairment clinical trials by Ritchie, Marina, Gillen, Daniel L, Grill, Joshua D

“…Participant retention is a key factor that affects clinical trial integrity. Trial protocols estimate attrition as a function of sample size calculations…”
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Deficient liver biosynthesis of docosahexaenoic acid correlates with cognitive impairment in Alzheimer's disease by Astarita, Giuseppe, Jung, Kwang-Mook, Berchtold, Nicole C, Nguyen, Vinh Q, Gillen, Daniel L, Head, Elizabeth, Cotman, Carl W, Piomelli, Daniele

“…Reduced brain levels of docosahexaenoic acid (C22:6n-3), a neurotrophic and neuroprotective fatty acid, may contribute to cognitive decline in Alzheimer's…”
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Recruitment across two decades of NIH-funded Alzheimer's disease clinical trials by Ritchie, Marina, Gillen, Daniel L, Grill, Joshua D

“…Timely accrual of a representative sample is a key factor in whether Alzheimer's disease (AD) clinical trials successfully answer the scientific questions…”
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Associations between microvascular function and short-term exposure to traffic-related air pollution and particulate matter oxidative potential by Zhang, Xian, Staimer, Norbert, Tjoa, Tomas, Gillen, Daniel L, Schauer, James J, Shafer, Martin M, Hasheminassab, Sina, Pakbin, Payam, Longhurst, John, Sioutas, Constantinos, Delfino, Ralph J

“…Short-term exposure to ambient air pollution has been associated with acute increases in cardiovascular hospitalization and mortality. However, causative…”
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Frameworks for estimating causal effects in observational settings: comparing confounder adjustment and instrumental variables by Zawadzki, Roy S, Grill, Joshua D, Gillen, Daniel L

“…To estimate causal effects, analysts performing observational studies in health settings utilize several strategies to mitigate bias due to confounding by…”
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Recruitment and retention of participant and study partner dyads in two multinational Alzheimer's disease registration trials by Bernstein, Olivia M, Grill, Joshua D, Gillen, Daniel L

“…Early study exit is detrimental to statistical power and increases the risk for bias in Alzheimer's disease clinical trials. Previous analyses in early phase…”
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RITS: a toolbox for assessing complex interventions via interrupted time series models by Cruz, Maricela, Pinto-Orellana, Marco A, Gillen, Daniel L, Ombao, Hernando C

“…Various interacting and interdependent components comprise complex interventions. These components create difficulty in assessing the true impact of…”
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Placental Corticotrophin-Releasing Hormone is a Modulator of Fetal Liver Blood Perfusion by Ikenoue, Satoru, Waffarn, Feizal, Ohashi, Masanao, Tanaka, Mamoru, Gillen, Daniel L, Buss, Claudia, Entringer, Sonja, Wadhwa, Pathik D

“…Abstract Context Variation in fetal liver blood flow influences fetal growth and postnatal body composition. Placental corticotrophin-releasing hormone has…”
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Tyrosinase Depletion Prevents the Maturation of Melanosomes in the Mouse Hair Follicle by Paterson, Elyse K, Fielder, Thomas J, MacGregor, Grant R, Ito, Shosuke, Wakamatsu, Kazumasa, Gillen, Daniel L, Eby, Victoria, Boissy, Raymond E, Ganesan, Anand K

“…The mechanisms that lead to variation in human skin and hair color are not fully understood. To better understand the molecular control of skin and hair color…”
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Down syndrome and dementia: A randomized, controlled trial of antioxidant supplementation by Lott, Ira T., Doran, Eric, Nguyen, Vinh Q., Tournay, Anne, Head, Elizabeth, Gillen, Daniel L.

“…Individuals with Down syndrome over age 40 years are at risk for developing dementia of the Alzheimer type and have evidence for chronic oxidative stress…”
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The RhoJ-BAD signaling network: An Achilles' heel for BRAF mutant melanomas by Ruiz, Rolando, Jahid, Sohail, Harris, Melissa, Marzese, Diego M, Espitia, Francisco, Vasudeva, Priya, Chen, Chi-Fen, de Feraudy, Sebastien, Wu, Jie, Gillen, Daniel L, Krasieva, Tatiana B, Tromberg, Bruce J, Pavan, William J, Hoon, Dave S, Ganesan, Anand K

“…Genes and pathways that allow cells to cope with oncogene-induced stress represent selective cancer therapeutic targets that remain largely undiscovered. In…”
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Body mass index and mortality in kidney transplant recipients: a systematic review and meta-analysis by Ahmadi, Seyed-Foad, Zahmatkesh, Golara, Streja, Elani, Molnar, Miklos Z, Rhee, Connie M, Kovesdy, Csaba P, Gillen, Daniel L, Steiner, Shah, Kalantar-Zadeh, Kamyar

“…A higher body mass index (BMI) seems to be linked to survival advantage in maintenance hemodialysis patients. However, it is uncertain if this 'obesity…”
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Difluoromethylornithine plus sulindac for the prevention of sporadic colorectal adenomas: a randomized placebo-controlled, double-blind trial by Meyskens, Jr, Frank L, McLaren, Christine E, Pelot, Daniel, Fujikawa-Brooks, Sharon, Carpenter, Philip M, Hawk, Ernest, Kelloff, Gary, Lawson, Michael J, Kidao, Jayashri, McCracken, John, Albers, C Gregory, Ahnen, Dennis J, Turgeon, D Kim, Goldschmid, Steven, Lance, Peter, Hagedorn, Curt H, Gillen, Daniel L, Gerner, Eugene W

“…Preclinical studies of chemoprevention drugs given in combination at low doses show remarkable efficacy in preventing adenomas with little additional…”
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Study partner types and prediction of cognitive performance: implications to preclinical Alzheimer's trials by Nuño, Michelle M, Gillen, Daniel L, Grill, Joshua D

“…Alzheimer's disease (AD) clinical trials require enrollment of a participant and a study partner, whose role includes assessing participant cognitive and…”
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Racial and ethnic differences in older adults’ willingness to be contacted about Alzheimer's disease research participation by Salazar, Christian R., Hoang, Dan, Gillen, Daniel L., Grill, Joshua D.

“…Introduction We sought to examine the association of race/ethnicity with willingness to engage in studies that involve procedures typical of Alzheimer's…”
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Prospective association of fetal liver blood flow at 30 weeks gestation with newborn adiposity by Ikenoue, Satoru, MD, PhD, Waffarn, Feizal, MD, Ohashi, Masanao, MD, PhD, Sumiyoshi, Kaeko, MD, Ikenoue, Chigusa, MD, Buss, Claudia, PhD, Gillen, Daniel L., PhD, Simhan, Hyagriv N., MD, MSc, Entringer, Sonja, PhD, Wadhwa, Pathik D., MD, PhD

“…Background The production of variation in adipose tissue accretion represents a key fetal adaptation to energy substrate availability during gestation. Because…”
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