Search Results - "Gillard, Geoff O."

Reversing Clonal Hematopoiesis and Associated Atherosclerotic Disease By Targeted Antibody-Drug-Conjugate (ADC) Conditioning and Transplant by Gustafsson, Karin, Rhee, Catherine S, Scadden, Elizabeth W, Frodermann, Vanessa, Palchaudhuri, Rahul, Hyzy, Sharon L., Proctor, Jennifer L, Gillard, Geoff O, Boitano, Anthony E, Cooke, Michael P., Nahrendorf, Matthias, Scadden, David T.

“…Cardiovascular disease (CVD) is the leading cause of death worldwide. Recently, age-related clonal hematopoiesis (CH) has been recognized as a risk factor for…”
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Single Agent CD45-Targeted Antibody Drug Conjugate Enables Full Mismatch Allogeneic Hematopoietic Stem Cell Transplantation in a Murine HSCT Model by Hyzy, Sharon L., Proctor, Jennifer L, Gillard, Geoff O, Hammond, Katelyn J., Sarma, Ganapathy N., Saha, Asim, Clark, Nicholas, Bhat, Anjali, Lamothe, Tahirih L, Palchaudhuri, Rahul, Pearse, Bradley R, McDonagh, Charlotte F, Kiem, Hans-Peter, Wagner, John E, Blazar, Bruce R., Boitano, Anthony E, Cooke, Michael P, Davis, John C.

“…Introduction Allogeneic hematopoietic stem cell transplant (Allo-HSCT) is a potentially curative treatment for malignant and non-malignant blood disorders…”
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A Novel Targeted Approach to Achieve Immune System Reset: CD45-Targeted Antibody Drug Conjugates Enable Autologous HSCT, Ameliorate Disease in Autoimmune Models, Potently Kill Human Immune Cells from Normal Donors and MS Patients, and Achieve Immune Depletion in Non-Human Primates (NHP) by Gillard, Geoff O, Proctor, Jennifer L, Brooks, Melissa L., Lamothe, Tahirih L, Hyzy, Sharon L., Mikse, Oliver, McDonough, Sean, Palchaudhuri, Rahul, Bhat, Anjali, Sarma, Ganapathy N., Bhattarai, Prashant, Sawant, Pranoti, Pearse, Bradley R, Mcdonough, Charlotte F., Boitano, Anthony E., Cooke, Michael P.

“…Resetting the immune system through autologous hematopoietic stem cell transplant (autoHSCT) is a highly effective treatment in selected patients with…”
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Successful Allogeneic Hematopoietic Stem Cell Transplantation in Mice Mediated By Well-Tolerated Conditioning Regimens Based on CD45-Targeted Antibody Drug Conjugate: Implications for Haplo Transplantation by Hyzy, Sharon L., Palchaudhuri, Rahul, Proctor, Jennifer L., Pearse, Bradley R., Sarma, Ganapathy N., Gillard, Geoff O., Saha, Asim, Lamothe, Tahirih L., Brooks, Melissa L., Hammond, Katelyn, Bhat, Anjali, Clark, Nicholas, McDonagh, Charlotte F., Kiem, Hans-Peter, Wagner, John E., Blazar, Bruce R., Boitano, Anthony E., Cooke, Michael P.

“…Allogeneic hematopoietic stem cell transplant (Allo-HSCT) is a potentially curative treatment for malignant and non-malignant blood disorders. However, current…”
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CD45-Targeted Antibody Drug Conjugate Plus Post Transplant Cytoxan Is Sufficient to Enable Allogeneic Bone Marrow Transplant in a Minor Mismatch Mouse Model by Hyzy, Sharon L., Palchaudhuri, Rahul, Proctor, Jennifer L., Pearse, Brad R., Sarma, Ganapathy N., Adams, Hillary L., Aslanian, Sharon, Gillard, Geoff O., Lamothe, Tahirih L., Burenkova, Olga, Brooks, Melissa, Gabros, Andrew D., McDonagh, Charlotte F., Boitano, Anthony E., Cooke, Michael P.

“…Bone Marrow Transplant (BMT) is a potentially curative treatment for malignant and non-malignant blood disorders. Current regimens for patient preparation, or…”
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Non-Genotoxic Conditioning Using Amanitin Antibody-Drug Conjugates Targeting CD45 Effectively Deplete Human and Non-Human Primate Hematopoietic Stem Cells and Immune Cells by Palchaudhuri, Rahul, Pearse, Brad R., Proctor, Jennifer L., Hyzy, Sharon L., Aslanian, Sharon, Bhat, Anjali, Gillard, Geoff O, McDonough, Sean M., Sarma, Ganapathy N, Ladwig, Danielle, Li, Qing, Jain, Nidhi, Panwar, Rajiv, Sawant, Pranoti, Dushime, Junia, Falahee, Patrick C., Kien, Lena, Lamothe, Tahirih L, Gabros, Andrew D, Adams, Hillary L., McDonagh, Charlotte F, Boitano, Anthony E., Cooke, Michael P.

“…Bone Marrow Transplant (BMT) is a potentially curative treatment for malignant and non-malignant blood disorders. Current regimens for patient preparation, or…”
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