Search Results - "Gillam, Janet"

Synthesis of hexahydrocyclopentimidazol-2-(1 H)-one derivatives displaying selective DP-receptor agonist properties by Barraclough, Paul, Bolofo, Mary L., Giles, Heather, Gillam, Janet, John Harris, C., Kelly, Michael G., Leff, Paul, McNeill, Alan, Robertson, Alan D., Stepney, Ray J., Whittle, Brendan J.R.

“…The rationale for investigating conformationally restricted analogues of BW245C as DP-receptor ligands and the syntheses of three such racemic bicyclic…”
Get full text

Synthesis of a hexahydro-2 H-imidazo[4,5- g]isoquinolin-2-one derivative as an isostere of catecholamine-based selective dopamine D-1 antagonists by Denyer, Clive V, Bunyan, Hazel, Loakes, David M, Tucker, Jacqueline, Gillam, Janet

“…The synthesis of the racemic hexahydro-2 H-imidazo [4,5- g] isoquinolin-2-one 15 (BW2247W94), a 6,7-ureylene isostere of the…”
Get full text

Characterisation of the conformational and tautomeric properties of benzylamino derivatives of 1,4-diphenyl-2-butene-1,4-dione using NMR spectroscopy by Abu-Orabi, Sultan T., Salman, Salman R., Gillam, Janet M., Lindon, John C.

“…The 1H and 13C NMR chemical shifts of substituted 1,4-dephenyl-2-butene-1,4-diones indicate that these compounds in CDCl 3 solution exist mainly in the s-…”
Get full text

Synthesis of a hexahydro-2H-imidazo[4,5-g]isoquinolin-2-one derivative as an isostere of catecholamine-based selective dopamine D-1 antagonists by Denyer, Clive V, Bunyan, Hazel, Loakes, David M, Tucker, Jacqueline, Gillam, Janet

Get full text

Isosteres of the DNA polymerase inhibitor aphidicolin as potential antiviral agents against human herpes viruses by Selwood, David L, Challand, S. Richard, Champness, John N, Gillam, Janet, Hibberd, Deborah K, Jandu, K. Singh, Lowe, Denise, Pether, Michael, Selway, John, Trantor, George E

“…A variety of isosteres of the DNA polymerase inhibitor aphidicolin were synthesized as potential antiherpes agents. Modeling studies indicated that the…”
Get full text

Inotropic polyazapentalene sulmazole analogues by Barraclough, P, Black, J W, Cambridge, D, Firmin, D, Gerskowitch, V P, Glen, R C, Giles, H, Gillam, J M, Hull, R A, Iyer, R

“…Aryl substituted 1H-imidazo[1,2-a]imidazole 8, imidazo[2,1-b]thiazole 9, 1,4-dihydroimidazo[4,5-d]imidazole 11, and 1(2),4-dihydroimidazo[4,5-c]pyrazoles 12-17…”
Get more information

Selective Inverse-Detected Long-Range HeteronuclearJ-Resolved NMR Spectroscopy and Its Application to the Measurement of3JCH by Liu, Maili, Farrant, R.Duncan, Gillam, Janet M., Nicholson, Jeremy K., Lindon, John C.

“…A new method for measuring and assigning long-range1H–13C spin coupling constants is presented. This is based on the HSQC pulse sequence with substitution of…”
Get full text