Search Results - "Gill, Ss"

Convection enhanced delivery of panobinostat (LBH589)-loaded pluronic nano-micelles prolongs survival in the F98 rat glioma model by Singleton, W G, Collins, A M, Bienemann, A S, Killick-Cole, C L, Haynes, H R, Asby, D J, Butts, C P, Wyatt, M J, Barua, N U, Gill, S S

“…The pan-histone deacetylase inhibitor panobinostat is a potential therapy for malignant glioma, but it is water insoluble and does not cross the blood-brain…”
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Gene Expression Changes Induced in Mouse Liver by Di(2-ethylhexyl) Phthalate by Wong, Jean S., Gill, Sarjeet S.

“…Increasing chemical use necessitates a better understanding of how pollutants, such as di(2-ethylhexyl) phthalate (DEHP), a peroxisome proliferator and a…”
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Design of Transfer Learning based Deep CNN Paradigm for Brain Tumor Classification by Bhardwaj, Neha, Sood, Meenakshi, Gill, Ss

“…Brain tumor is a fatal illness causing worldwide fatalities. The existing neuroimaging modalities to detect brain tumors are invasive and are observer-biased…”
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Bilateral deep brain stimulation of the pedunculopontine nucleus for Parkinsonʼs disease by Plaha, Puneet, Gill, Steven S

“…Gait disturbance and postural instability are some the most disabling symptoms of idiopathic Parkinsonʼs disease and in late stage disease can be resistant to…”
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DISASTER MANAGEMENT IN RADIOLOGY DEPARTMENT by Kumar, Gupta Lalit, Varshdeep, Kour, Pankaj, Koul, Gill, SS

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Intake of vitamin E, vitamin C, and carotenoids and the risk of Parkinson's disease: a meta-analysis by Etminan, Mahyar, Gill, Sudeep S, Samii, Ali

“…We studied the effect of vitamin C, vitamin E, and beta carotene intake on the risk of Parkinson's disease (PD). We did a systematic review and meta-analysis…”
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Intraputamenal infusion of glial cell line-derived neurotrophic factor in PD: A two-year outcome study by Patel, Nikunj K., Bunnage, Martin, Plaha, Puneet, Svendsen, Clive N., Heywood, Peter, Gill, Steven S.

“…We have shown previously that intraparenchymal infusion of glial cell line–derived neurotrophic factor (GDNF) continuously into the posterior putamen in five…”
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Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease by Gill, Steven S, Svendsen, Clive N, Patel, Nikunj K, Hotton, Gary R, O'Sullivan, Karen, McCarter, Renée, Bunnage, Martin, Brooks, David J, Heywood, Peter

“…Glial cell line-derived neurotrophic factor (GDNF) is a potent neurotrophic factor with restorative effects in a wide variety of rodent and primate models of…”
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Oligomerization triggers binding of a Bacillus thuringiensis Cry1Ab pore-forming toxin to aminopeptidase N receptor leading to insertion into membrane microdomains by Bravo, A., Gómez, I., Conde, J., Muñoz-Garay, C., Sánchez, J., Miranda, R., Zhuang, M., Gill, S.S., Soberón, M.

“…Bacillus thuringiensis Cry1A toxins, in contrast to other pore-forming toxins, bind two putative receptor molecules, aminopeptidase N (APN) and cadherin-like…”
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Glial cell line-derived neurotrophic factor induces neuronal sprouting in human brain by Love, Seth, Plaha, Puneet, Patel, Nikunj K, Hotton, Gary R, Brooks, David J, Gill, Steven S

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Atypical antipsychotic drugs and risk of ischaemic stroke: population based retrospective cohort study by Gill, Sudeep S, Rochon, Paula A, Herrmann, Nathan, Lee, Philip E, Sykora, Kathy, Gunraj, Nadia, Normand, Sharon-Lise T, Gurwitz, Jerry H, Marras, Connie, Wodchis, Walter P, Mamdani, Muhammad

“…Abstract Objective To compare the incidence of admissions to hospital for stroke among older adults with dementia receiving atypical or typical antipsychotics…”
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Bacillus thuringiensis subsp. israelensis Cyt1Aa synergizes Cry11Aa toxin by functioning as a membrane-bound receptor by Perez, C, Fernandez, L.E, Sun, J, Folch, J.L, Gill, S.S, Soberon, M, Bravo, A

“…Bacillus thuringiensis subsp. israelensis produces crystal proteins, Cry (4Aa, 4Ba, 10Aa, and 11Aa) and Cyt (1Aa and 2Ba) proteins, toxic to mosquito vectors…”
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Atypical antipsychotic drugs in the treatment of behavioural and psychological symptoms of dementia: systematic review by Lee, Philip E, Gill, Sudeep S, Freedman, Morris, Bronskill, Susan E, Hillmer, Michael P, Rochon, Paula A

“…Abstract Objective To review the role of oral atypical antipsychotic drugs in the management of the behavioural and psychological symptoms of dementia (BPSD)…”
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A GPI-anchored alkaline phosphatase is a functional midgut receptor of Cry11Aa toxin in Aedes aegypti larvae by Fernandez, Luisa E, Aimanova, Karlygash G, Gill, Sarjeet S, Bravo, Alejandra, Soberón, Mario

“…A 65 kDa GPI (glycosylphosphatidyl-inositol)-anchored ALP (alkaline phosphatase) was characterized as a functional receptor of the Bacillus thuringiensis…”
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DIPG-42. THE COMBINATION OF THE CDK4/6 INHIBITOR PALBOCICLIB WITH THE RAPALOGUE TEMSIROLIMUS INHIBITS DIPG CELL PROLIFERATION VIA SYNERGISTIC ATTENUATION OF CELL CYCLE REGULATORS by Asby, DJ, Bienemann, AS, Wright, LJ, Killick-Cole, C, Singleton, WGB, Wyatt, MJ, Barua, NU, Gill, SS

“…Current chemotherapy for diffuse intrinsic pontine glioma (DIPG) is ineffective and requires revitalization. DIPG accounts for up to 15% of all childhood…”
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TRTH-07. THE DISTRIBUTION, CLEARANCE AND TOXICITY OF PANOBINOSTAT ADMINISTERED TO JUVENILE RAT AND PIG BRAINSTEM BY CONVECTION ENHANCED DELIVERY by Singleton, WGB, Bienemann, AS, Wooley, M, Johnson, D, Lewis, O, Wyatt, MJ, White, LJ, Damment, SJP, Killick-Cole, C, Asby, DJ, Gill, SS

“…The pan-histone deacetylase inhibitor panobinostat has preclinical efficacy against DIPG and the oral formulation has entered a phase one clinical trial…”
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Combined use of CDK4/6 and mTOR inhibitors induce synergistic growth arrest of diffuse intrinsic pontine glioma cells via mutual downregulation of mTORC1 activity by Asby, Daniel J, Killick-Cole, Clare L, Boulter, Lisa J, Singleton, William Gb, Asby, Claire A, Wyatt, Marcella J, Barua, Neil U, Bienemann, Alison S, Gill, Steven S

“…Diffuse intrinsic pontine glioma (DIPG) is a lethal type of pediatric brain tumor that is resistant to conventional chemotherapies. Palbociclib is a putative…”
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Nursing Home Profit Status and Quality of Care: Is There Any Evidence of an Association? by Hillmer, Michael P., Wodchis, Walter P., Gill, Sudeep S., Anderson, Geoffrey M., Rochon, Paula A.

“…This article critically reviews the association between the profit status of North American nursing homes and the quality of care. Studies were identified by…”
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Stimulation of the subthalamic region for essential tremor by PLAHA, Puneet, PATEL, Nikunj K, GILL, Steven S

“…The goal of this study was to determine the safety and efficacy of bilateral subthalamic region stimulation in the treatment of essential tremor (ET)…”
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Unilateral subthalamotomy in the treatment of Parkinson’s disease by Patel, Nikunj K., Heywood, Peter, O’Sullivan, Karen, McCarter, Renée, Love, Seth, Gill, Steven S.

“…Hyperactivity in the subthalamic nucleus (STN) is seen in animal models of Parkinson’s disease, and lesioning of the STN dramatically relieves the animal’s…”
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