Search Results - "Gill, Rosalynn D"
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Improved weight management using genetic information to personalize a calorie controlled diet
Published in Nutrition journal (18-10-2007)“…Gene-environment studies demonstrate variability in nutrient requirements depending upon individual variations in genes affecting nutrient metabolism and…”
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Effects of Delivering SLCO1B1 Pharmacogenetic Information in Randomized Trial and Observational Settings
Published in Circulation. Genomic and precision medicine (01-09-2018)“…Outcomes of tailoring statin-type based on solute carrier organic anion transporterfamily member 1B1 ( SLCO1B1)pharmacogenetic toxicity information on patient,…”
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3
Evolving concepts and techniques for anti-doping
Published in Bioanalysis (01-07-2012)“…Technical advances are being made in many areas of biotechnology and genetics that are facilitating the detection of doping in sport. These improvements have…”
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Abstract 10244: Heartmatters Challenge: Therapeutic Lifestyle Program Reduces Cardiovascular Risk Factors and Weight in First Responders Using Personalized Nutrition, Phone-based Coaching and Online Food Journaling
Published in Circulation (New York, N.Y.) (10-11-2015)“…ObjectivePremature CVD death is common among first responders. Effective risk reduction programs are urgently needed to address this public health concern. We…”
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Preoteomic insights in oncology: What have we learned from measuring millions of proteins?
Published in Journal of clinical oncology (20-05-2012)“…Abstract only e21142 Background: We have assayed over 8400 blood samples from 10 different malignancies, generating over 8 million quantitative protein…”
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Exposing the criminal record of every blood sample: Use of SOMAmer technology and sample mapping vectors to mitigate false biomarker discoveries in lung cancer
Published in Journal of clinical oncology (20-05-2012)“…Abstract only e21012 Background: Biomarker discovery studies may fail to translate to the clinic because the study population does not match the intended…”
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Construction of Escherichia coli vectors containing deoxyadenosine and deoxyguanosine adducts from (+)-anti-dibenz[a,j]anthracene diol epoxide at a defined site
Published in Chemical research in toxicology (01-09-1993)“…Dibenz[a,j]anthracene (DB[a,j]A) is a carcinogenic polycylic aromatic hydrocarbon, which is metabolically activated through the formation of bay region diol…”
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Characterization of DNA adducts derived from (.+-.)-trans-3,4-dihydroxy-anti-1,2-epoxy-1,2,3,4-tetrahydrodibenz[a,j]anthracene and (.+-.)-7-methyl-trans-3,4-dihydroxy-anti-1,2-epoxy-1,2,3,4-tetrahydrodibenz[a,j]anthracene
Published in Chemical research in toxicology (01-09-1989)“…Structural characterizations of the DNA adducts derived from reaction of the racemic bay region anti-diol epoxides of dibenz[a,j]anthracene and…”
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Characterization of covalently modified deoxyribonucleosides formed from dibenz[a,j]anthracene in primary cultures of mouse keratinocytes
Published in Chemical research in toxicology (01-01-1991)“…Identification of various deoxyribonucleoside adducts formed in primary cultures of mouse keratinocytes exposed to dibenz[a,j]anthracene (DB[a,j]A) is…”
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Excision repair of nitrogen mustard-DNA adducts in Saccharomyces cerevisiae
Published in Nucleic acids research (15-08-1999)“…The bifunctional alkylating anticancer drug nitrogen mustard forms a variety of DNA lesions, including monoadducts and intrastrand and interstrand crosslinks…”
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Excision repair of nitrogen mustard-DNA adducts inSaccharomyces cerevisiae
Published in Nucleic acids research (01-08-1999)“…The bifunctional alkylating anticancer drug nitrogen mustard forms a variety of DNA lesions, including monoadducts and intrastrand and interstrand crosslinks…”
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Targeted A → T and G → T Mutations Induced by Site-Specific Deoxyadenosine and Deoxyguanosine Adducts, Respectively, from the (+)-anti-Diol Epoxide of Dibenz[a,j]anthracene in M13mp7L2
Published in Biochemistry (Easton) (02-04-1996)“…The studies described in this report directly examined the mutagenicity in Escherichia coli of both a deoxyadenosine (dAdo) and a deoxyguanosine (dGuo) adduct…”
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Further analysis of c-Ha-ras mutations in papillomas initiated by several polycyclic aromatic hydrocarbons and papillomas from uninitiated, promoter-treated skin in SENCAR mice
Published in Molecular carcinogenesis (1993)“…In this study we analyzed the mutations in c-Ha-ras from skin papillomas initiated with benzo[a]pyrene (B[a]P), 7-methylbenz[a]anthracene (7-MBA), and…”
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Analysis of point mutations in murine c-Ha-ras of skin tumors initiated with dibenz[a,j]anthracene and derivatives
Published in Molecular carcinogenesis (1992)“…This study was designed to evaluate the point mutations in the murine c-Ha-ras gene of skin papillomas induced by initiation with dibenz[a,j]anthracene…”
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Mutagenic specificity of the (+)anti-diol epoxide of dibenz[a,j]anthracene in the supF gene of an Escherichia coli plasmid
Published in Molecular carcinogenesis (1993)“…This study was designed to examine the mutagenic specificity of (+)anti-dibenz[a,j]anthracene 3,4-diol-1,2-epoxide ((+)anti-DB[a,j]A-DE) in SOS-induced…”
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Relationship between DNA adduct formation and unscheduled DNA synthesis (UDS) in cultured mouse epidermal keratinocytes
Published in Environmental and molecular mutagenesis (1991)“…Primary cultures of mouse epidermal keratinocytes from SENCAR mice were treated with 7,12-dimethylbenz(a)anthracene (DMBA), benzo(a)pyrene [B(a)P], (+/-)7…”
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