Search Results - "Gill, Michelle A"
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Cutting Edge: Critical Role of Glycolysis in Human Plasmacytoid Dendritic Cell Antiviral Responses
Published in The Journal of immunology (1950) (01-03-2016)“…Plasmacytoid dendritic cells (pDCs) are vital to antiviral defense, directing immune responses via secretion of huge concentrations of IFN-α. These cells are…”
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Eosinophil-mediated suppression and anti–IL-5 enhancement of plasmacytoid dendritic cell interferon responses in asthma
Published in Journal of allergy and clinical immunology (01-09-2022)“…Virus-induced IFN-α secretion by plasmacytoid dendritic cells (pDCs) is negatively impacted by IgE and has been linked to asthma exacerbations. Eosinophils,…”
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Distinct RIG-I and MDA5 Signaling by RNA Viruses in Innate Immunity
Published in Journal of Virology (01-01-2008)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Innate immune responses to rhinovirus are reduced by the high-affinity IgE receptor in allergic asthmatic children
Published in Journal of allergy and clinical immunology (01-08-2012)“…Background Children with allergic asthma have more frequent and severe human rhinovirus (HRV)–induced wheezing and asthma exacerbations through unclear…”
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Cutting edge: Type I IFN reverses human Th2 commitment and stability by suppressing GATA3
Published in The Journal of immunology (1950) (15-07-2010)“…T helper 2 cells regulate inflammatory responses to helminth infections while also mediating pathological processes of asthma and allergy. IL-4 promotes Th2…”
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Adrenergic Signaling at the Interface of Allergic Asthma and Viral Infections
Published in Frontiers in immunology (11-04-2018)“…Upper respiratory viral infections are a major etiologic instigator of allergic asthma, and they drive severe exacerbations of allergic inflammation in the…”
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Differential Recruitment of Dendritic Cells and Monocytes to Respiratory Mucosal Sites in Children with Influenza Virus or Respiratory Syncytial Virus Infection
Published in The Journal of infectious diseases (01-12-2008)“…Background. Influenza virus and respiratory syncytial virus (RSV) are among the most common viruses causing infections of the lower respiratory tract in young…”
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IgE cross-linking impairs monocyte antiviral responses and inhibits influenza-driven Th1 differentiation
Published in Journal of allergy and clinical immunology (01-07-2017)“…Capsule Summary: IgE-mediated allergic activation impairs the virus-induced Th1 lymphocyte priming capacity of human monocytes in response to influenza…”
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Granular Insights: Neutrophil Predominance and Elastase Release in Severe Asthma Exacerbations in a Pediatric Cohort
Published in Cells (Basel, Switzerland) (01-03-2024)“…The chronic inflammatory component of asthma is propagated by granulocytes, including neutrophils and eosinophils, in the peripheral circulation and airway…”
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IgE cross-linking critically impairs human monocyte function by blocking phagocytosis
Published in Journal of allergy and clinical immunology (01-02-2013)“…Background IgE cross-linking triggers many cellular processes that drive allergic disease. While the role of IgE in mediating allergic responses is best…”
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Obstructive hydrocephalus and intracerebral mass secondary to Epicoccum nigrum
Published in Medical mycology case reports (01-03-2022)“…Here we report a case of a 14-week-old girl with a history of intrauterine drug exposure and hypoxic ischemic encephalopathy secondary to cardiac arrest…”
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Mobilization of Plasmacytoid and Myeloid Dendritic Cells to Mucosal Sites in Children with Respiratory Syncytial Virus and Other Viral Respiratory Infections
Published in The Journal of infectious diseases (01-04-2005)“…Background Respiratory syncytial virus (RSV) is the principal etiologic agent of bronchiolitis and viral pneumonia in infants and young children. Yet, many…”
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Expression of Corticosteroid Regulated Genes By Peripheral Blood Mononuclear Cells (PBMCs) in Children from the NIH/Niaid Sponsored Asthma Phenotypes in the Inner City (APIC) Study after One Year of Guidelines-Based Therapy
Published in Journal of allergy and clinical immunology (01-02-2016)“…PBMC expression of glucocorticoid receptor alpha (GRalpha), corticosteroid transactivation (FK binding protein 5 (FKBP5)) and transrepression markers (IL-8,…”
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Enhanced plasmacytoid dendritic cell antiviral responses after omalizumab
Published in Journal of allergy and clinical immunology (01-05-2018)“…Atopy and viral respiratory tract infections synergistically promote asthma exacerbations. IgE cross-linking inhibits critical virus-induced IFN-α responses of…”
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Motavizumab for the prevention of respiratory syncytial virus infection in infants
Published in Expert opinion on biological therapy (01-10-2009)“…Respiratory syncytial virus (RSV) is the most important respiratory viral pathogen of infancy. The only unequivocally effective pharmacological compound for…”
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Endotypes of Difficult-to-Control Asthma in Inner City Children Differ By Race
Published in Journal of allergy and clinical immunology (01-02-2016)“…[...]treatment regimens that specifically target inflammatory pathways characteristic of asthma severity in African Americans may be beneficial in treating…”
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Associations Between The Expression Of Corticosteroid Regulated Genes By Peripheral Blood Mononuclear Cells (PBMCs) In Children From The NIH/NIAID Sponsored Asthma Phenotypes In The Inner City (APIC) Study
Published in Journal of allergy and clinical immunology (01-02-2014)Get full text
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Preseasonal treatment with either omalizumab or an inhaled corticosteroid boost to prevent fall asthma exacerbations
Published in Journal of allergy and clinical immunology (01-12-2015)“…Background Short-term targeted treatment can potentially prevent fall asthma exacerbations while limiting therapy exposure. Objective We sought to compare (1)…”
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Mepolizumab for urban children with exacerbation-prone eosinophilic asthma in the USA (MUPPITS-2): a randomised, double-blind, placebo-controlled, parallel-group trial
Published in The Lancet (British edition) (13-08-2022)“…Black and Hispanic children living in urban environments in the USA have an excess burden of morbidity and mortality from asthma. Therapies directed at the…”
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Transcriptome networks identify mechanisms of viral and nonviral asthma exacerbations in children
Published in Nature immunology (01-05-2019)“…Respiratory infections are common precursors to asthma exacerbations in children, but molecular immune responses that determine whether and how an infection…”
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