Search Results - "Gill, Jonathan Benjamin"
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A phase 1 dose escalation trial of ex-vivo expanded allogeneic cord blood–derived natural killer cell immunotherapy for pediatric solid tumor malignancies
Published in Journal of clinical oncology (01-06-2023)“…2546 Background: Despite aggressive multimodality therapy, survival outcomes of most patients with recurrent/refractory solid tumors remain dismal. Preclinical…”
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Abstract 3110: ICAM-1(CD54) mediated bi-lineage differentiation in osteosarcoma
Published in Cancer research (Chicago, Ill.) (01-07-2021)“…Introduction: Osteosarcoma (OS) is the most common primary bone tumor in children and adolescents. The cell of origin in OS is still not known, however, OS…”
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Clinical characteristics and outcomes of adult alveolar rhabdomyosarcoma (ARMS) patients on front-line therapies: An MD Anderson Cancer Center (MDACC) case series
Published in Journal of clinical oncology (01-06-2022)“…e23548 Background: Rhabdomyosarcomas are the most common soft tissue sarcoma in children, and the prognosis of pediatric ARMS has improved with the use of…”
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Abstract 82: Transforming of human osteoblasts with the combination of hTERT (T), SV40Tag (S) and c-Myc: Changes in phenotype and tumorigenesis capability
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…The etiology of osteosarcoma (OS), the most common primary malignant bone cancer in pediatric patients, still remains unknown. It is not clear where tat which…”
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Frequency and spectrum of clinically significant molecular alterations detected by tumor gene panel testing for pediatric cancer patients in the Texas KidsCanSeq study
Published in Journal of clinical oncology (01-06-2023)“…10018 Background: Tumor sequencing has the potential to inform diagnosis, prognosis, and treatment of childhood cancer patients. Prospective data are needed to…”
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Off label targeted therapy use in adolescents and young adults with sarcoma
Published in Journal of clinical oncology (20-05-2019)“…Abstract only e21504 Background: Outcomes for patients with metastatic or recurrent sarcomas remains dismal with < 20% overall survival. Due to the rarity of…”
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Evaluation of the TPO-receptor agonist Eltrombopag in the Pediatric Preclinical Testing Consortium osteosarcoma in vivo models
Published in Journal of clinical oncology (20-05-2019)“…Abstract only e22502 Background: Eltrombopag (EP) is a small molecule, thrombopoietin receptor (TPO-R) agonist indicated for the treatment of patients with…”
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A phase I trial of aerosol gemcitabine for the treatment of patients with solid tumors and lung metastases
Published in Journal of clinical oncology (20-05-2020)“…Abstract only TPS3645 Background: Pre-clinical studies of aerosol gemcitabine (GCB) in mice and dogs with osteosarcoma (OS) lung metastases demonstrated…”
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Cell-surface vimentin positive circulating tumor cells as a diagnostic and prognostic indicator in pediatric sarcoma patients
Published in Journal of clinical oncology (20-05-2021)“…Abstract only e15022 Background: Despite advances in care, the 5 year overall survival for patients with relapsed and or metastatic sarcoma remains as low as <…”
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Evaluation of the multi-kinase inhibitor regorafenib in the Pediatric Preclinical Testing Consortium osteosarcoma, rhabdomyosarcoma, and Ewing sarcoma in vivo models
Published in Journal of clinical oncology (20-05-2019)“…Abstract only 10038 Background: Regorafenib is a multi-kinase inhibitor, developed by adding a fluorine atom to the phenyl ring of sorafenib. Regorafenib…”
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Pediatric oncology provider views on biopsying solid tumors in children with relapsed or refractory disease for the purpose of genomic profiling
Published in Journal of clinical oncology (20-05-2016)“…Abstract only…”
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A phase I window, dose escalating and safety trial of metformin in combination with induction chemotherapy in relapsed refractory acute lymphoblastic leukemia: Metformin with induction chemotherapy of vincristine, dexamethasone, doxorubicin, and PEG-asparaginase (VPLD)
Published in Journal of clinical oncology (20-05-2016)“…Abstract only…”
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A bi-shRNA furin and GMCSF engineered autologous tumor cell immunotherapy vs. gemcitabine + docetaxel for Ewing sarcoma and with cryoablation in Ewing family tumors
Published in Journal of clinical oncology (20-05-2017)“…Abstract only TPS11079 Background: Vigil, an immuno-stimulatory autologous cellular therapy, uses patient tumor cells transfected with a plasmid encoding genes…”
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