Search Results - "Gill, G N"

The LIM-only factor LMO4 regulates expression of the BMP7 gene through an HDAC2-dependent mechanism, and controls cell proliferation and apoptosis of mammary epithelial cells by WANG, N, LIN, K. K, LU, Z, LAM, K. S, NEWTON, R, XU, X, YU, Z, GILL, G. N, ANDERSEN, B

“…The nuclear LIM-only protein 4 (LMO4) is upregulated in breast cancer, especially estrogen receptor-negative tumors, and its overexpression in mice leads to…”
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Enhanced Degradation of EGF Receptors by a Sorting Nexin, SNX1 by Kurten, Richard C., Cadena, Deborah L., Gill, Gordon N.

“…The vectorial movement of proteins requires specific recognition by components of the vesicular trafficking machinery. A protein, sorting nexin-1 (SNX1), was…”
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A Mutant Epidermal Growth Factor Receptor Common in Human Glioma Confers Enhanced Tumorigenicity by Nishikawa, R, Ji, X D, Harmon, R C, Lazar, C S, Gill, G N, Cavenee, W K, Huang, H J

“…The development and neoplastic progression of human astrocytic tumors appears to result through an accumulation of genetic alterations occurring in a…”
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Functional analysis of the nuclear LIM domain interactor NLI by Jurata, Linda W., Gill, Gordon N.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Nuclear LIM Interactor, a Rhombotin and LIM Homeodomain Interacting Protein, is Expressed Early in Neuronal Development by Jurata, Linda W., Kenny, Daryn A., Gill, Gordon N.

“…LIM domain-containing transcription factors, including the LIM-only rhombotins and LIM-homeodomain proteins, are crucial for cell fate determination of…”
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Receptor tyrosine kinases by Cadena, D L, Gill, G N

“…A major process through which environmental information is transmitted into cells is via activation of protein tyrosine kinases. Receptor tyrosine kinases…”
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The role of tyrosine kinase activity in endocytosis, compartmentation, and down-regulation of the epidermal growth factor receptor by WILEY, H. S, HERBST, J. J, WALSH, B. J, LAUFFENBURGER, D. A, ROSENFELD, M. G, GILL, G. N

“…Occupancy-induced down-regulation of cell surface epidermal growth factor (EGF) receptors attenuates signal transduction. To define mechanisms through which…”
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Biodiversity and the Indian Judiciary: Tracing the Trajectory by Gill, G. N., Chowdhury, N., Srivastava, N.

“…The Covid-19 narrative spotlights the necessity to conserve biological diversity (biodiversity) including ecosystems and wildlife. Biodiversity problems are…”
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C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated tyrosine protein kinase activity by Cochet, C, Gill, G N, Meisenhelder, J, Cooper, J A, Hunter, T

“…The Ca2+- and phospholipid-dependent protein kinase (C-kinase) binds tightly in the presence of Ca2+ to purified membranes of A431 human epidermoid carcinoma…”
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Interaction between the epidermal growth factor receptor and phosphoinositide kinases by Cochet, C, Filhol, O, Payrastre, B, Hunter, T, Gill, G N

“…Ligand-activated epidermal growth factor (EGF) receptors are coupled to the phosphatidylinositol (PtdIns) pathway to stimulate formation of two second…”
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Self-phosphorylation enhances the protein-tyrosine kinase activity of the epidermal growth factor receptor by Bertics, P J, Gill, G N

“…The effect of self-phosphorylation on the protein-tyrosine kinase activity of the epidermal growth factor receptor has been investigated using…”
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The intracellular tyrosine kinase domain of the epidermal growth factor receptor undergoes a conformational change upon autophosphorylation by Cadena, D L, Chan, C L, Gill, G N

“…The intracellular portion of the epidermal growth factor receptor consists of a tyrosine kinase domain of approximately 290 amino acids and a COOH-terminal…”
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Activation of the Purified Protein Tyrosine Kinase Domain of the Epidermal Growth Factor Receptor by Wedegaertner, P B, Gill, G N

“…Biological responses to epidermal growth factor (EGF) depend on the ligand-stimulated protein tyrosine kinase activity of its receptor. To further characterize…”
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Ligand-Induced Transformation by a Noninternalizing Epidermal Growth Factor Receptor by Wells, Alan, Welsh, John B., Lazar, Cheri S., Wiley, H. Steven, Gill, Gordon N., Rosenfeld, Michael G.

“…Identification of a mutant epidermal growth factor (EGF) receptor that does not undergo downregulation has provided a genetic probe to investigate the role of…”
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LIM domain recognition of a tyrosine-containing tight turn by Wu, R Y, Gill, G N

“…Endocytosis of cell surface receptors requires sequence "codes" consisting of tight turn structures with an essential Tyr or Phe residue. To determine…”
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Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics by Bokoch, Gary M, Edwards, David C, Sanders, Luraynne C, Gill, Gordon N

“…Extracellular signals regulate actin dynamics through small GTPases of the Rho/Rac/Cdc42 (p21) family. Here we show that p21-activated kinase (Pak1)…”
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Structural Features that Specify Tyrosine Kinase Activity Deduced from Homology Modeling of the Epidermal Growth Factor Receptor by Knighton, Daniel R., Cadena, Deborah L., Zheng, Jianhua, Lynn F. Ten Eyck, Taylor, Susan S., Sowadski, Janusz M., Gill, Gordon N.

“…To identify structural features that distinguish protein-tyrosine kinases from protein-serine kinases, a molecular model of the kinase domain of epidermal…”
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LIM Factor Lhx3 Contributes to the Specification of Motor Neuron and Interneuron Identity through Cell-Type-Specific Protein-Protein Interactions by Thaler, Joshua P., Lee, Soo-Kyung, Jurata, Linda W., Gill, Gordon N., Pfaff, Samuel L.

“…LIM homeodomain codes regulate the development of many cell types, though it is poorly understood how these factors control gene expression in a cell-specific…”
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Citation for the 1999 Fred Conrad Koch Award of the Endocrine Society to Dr. Ronald M. Evans and Dr. Michael G. Rosenfeld by Gill, G N

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Requirement for intrinsic protein tyrosine kinase in the immediate and late actions of the EGF receptor by Chen, William S, Lazar, Cheri S, Poenie, Martin, Tsien, Roger Y, Gill, Gordon N, Rosenfeld, Michael G

“…The epidermal growth factor (EGF) receptor is a transmembrane glycoprotein of relative molecular mass 170,000 with intrinsic ligand-dependent protein tyrosine…”
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