Search Results - "Gilius, Evan L"
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A single nucleotide polymorphism of the cholecystokinin-B receptor predicts risk for pancreatic cancer
Published in Cancer biology & therapy (01-02-2012)“…There currently are no tests available for early diagnosis or for the identification of patients at risk for development of pancreatic cancer. We report the…”
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Cholecystokinin Mediates Progression and Metastasis of Pancreatic Cancer Associated with Dietary Fat
Published in Digestive diseases and sciences (01-06-2014)“…Background Obesity and dietary fat are associated with increased risk of several malignancies including pancreatic cancer. The incidence of pancreatic cancer…”
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Cholecystokinin receptor antagonist halts progression of pancreatic cancer precursor lesions and fibrosis in mice
Published in Pancreas (01-10-2014)“…Exogenous administration of cholecystokinin (CCK) induces hypertrophy and hyperplasia of the pancreas with an increase in DNA content. We hypothesized that…”
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Downregulation of the CCK-B receptor in pancreatic cancer cells blocks proliferation and promotes apoptosis
Published in American journal of physiology: Gastrointestinal and liver physiology (01-06-2012)“…Gastrin stimulates the growth of pancreatic cancer cells through the activation of the cholecystokinin-B receptor (CCK-BR), which has been found to be…”
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PhotoImmunoNanoTherapy Reveals an Anticancer Role for Sphingosine Kinase 2 and Dihydrosphingosine-1-Phosphate
Published in ACS nano (26-03-2013)“…Tumor-associated inflammation mediates the development of a systemic immunosuppressive milieu that is a major obstacle to effective treatment of cancer…”
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Germline Mutation of the CCK Receptor: A Novel Biomarker for Pancreas Cancer
Published in Clinical and translational gastroenterology (01-01-2016)“…Today, genetic biomarkers have been demonstrated to play an important role in identifying at-risk subjects for familial or inherited cancers. We have…”
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