Search Results - "Giles, Keith E"

The Regulation of rRNA Gene Transcription during Directed Differentiation of Human Embryonic Stem Cells by Woolnough, Jessica L, Atwood, Blake L, Liu, Zhong, Zhao, Rui, Giles, Keith E

“…It has become increasingly clear that proper cellular control of pluripotency and differentiation is related to the regulation of rRNA synthesis. To further…”
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USP49 deubiquitinates histone H2B and regulates cotranscriptional pre-mRNA splicing by Zhang, Zhuo, Jones, Amanda, Joo, Heui-Yun, Zhou, Dewang, Cao, Ying, Chen, Shaoxia, Erdjument-Bromage, Hediye, Renfrow, Matthew, He, Hang, Tempst, Paul, Townes, Tim M, Giles, Keith E, Ma, Ligeng, Wang, Hengbin

“…Post-translational histone modifications play important roles in regulating chromatin structure and function. Histone H2B ubiquitination and deubiquitination…”
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Role of remodeling and spacing factor 1 in histone H2A ubiquitination-mediated gene silencing by Zhang, Zhuo, Jones, Amanda E., Wu, Wei, Kim, Jinman, Kang, Yue, Bi, Xiaobao, Gu, Yue, Popov, Ivan K., Renfrow, Matthew B., Vassylyeva, Marina N., Vassylyev, Dmitry G., Giles, Keith E., Chen, Dongquan, Kumar, Ashwath, Fan, Yuhong, Tong, Yufeng, Liu, Chuan-Fa, An, Woojin, Chang, Chenbei, Luo, Jianjun, Chow, Louise T., Wang, Hengbin

“…Posttranslational histone modifications play important roles in regulating chromatin-based nuclear processes. Histone H2AK119 ubiquitination (H2Aub) is a…”
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Human Argonaute 2 Is Tethered to Ribosomal RNA through MicroRNA Interactions by Atwood, Blake L., Woolnough, Jessica L., Lefevre, Gaelle M., Saint Just Ribeiro, Mariana, Felsenfeld, Gary, Giles, Keith E.

“…The primary role of the RNAi machinery is to promote mRNA degradation within the cytoplasm in a microRNA-dependent manner. However, both Dicer and the…”
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DNA·RNA triple helix formation can function as a cis-acting regulatory mechanism at the human β-globin locus by Zhou, Zhuo, Giles, Keith E., Felsenfeld, Gary

“…We have identified regulatory mechanisms in which an RNA transcript forms a DNA duplex·RNA triple helix with a gene or one of its regulatory elements,…”
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The histone H2A deubiquitinase Usp16 regulates embryonic stem cell gene expression and lineage commitment by Yang, Wei, Lee, Yun-Hwa, Jones, Amanda E., Woolnough, Jessica L., Zhou, Dewang, Dai, Qian, Wu, Qiang, Giles, Keith E., Townes, Tim M., Wang, Hengbin

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Retroviral Splicing Suppressor Sequesters a 3′ Splice Site in a 50S Aberrant Splicing Complex by Giles, Keith E., Beemon, Karen L.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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NETSeq reveals heterogeneous nucleotide incorporation by RNA polymerase I by Clarke, Andrew M., Engel, Krysta L., Giles, Keith E., Petit, Chad M., Schneider, David A.

“…DNA sequence motifs that affect RNA polymerase transcription elongation are well studied in prokaryotic organisms and contribute directly to regulation of gene…”
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Argonaute 2 Binds Directly to tRNA Genes and Promotes Gene Repression in cis by Woolnough, Jessica L., Atwood, Blake L., Giles, Keith E.

“…To further our understanding of the RNAi machinery within the human nucleus, we analyzed the chromatin and RNA binding of Argonaute 2 (AGO2) within human…”
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Maintenance of a constitutive heterochromatin domain in vertebrates by a Dicer-dependent mechanism by Felsenfeld, Gary, Giles, Keith E, Ghirlando, Rodolfo

“…The 16 kilobase (kb) heterochromatin domain between the chicken β-globin locus and the folate receptor gene is used here to study the roles of RNA-dependent…”
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The histone H2A deubiquitinase Usp16 regulates embryonic stem cell gene expression and lineage commitment by Yang, Wei, Lee, Yun-Hwa, Jones, Amanda E., Woolnough, Jessica L., Zhou, Dewang, Dai, Qian, Wu, Qiang, Giles, Keith E., Townes, Tim M., Wang, Hengbin

“…Polycomb Repressive Complex 1 and histone H2A ubiquitination (ubH2A) contribute to embryonic stem cell (ESC) pluripotency by repressing lineage-specific gene…”
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Dorsal column stimulation for pain relief from intractable angina pectoris by Murphy, Dermot F, Giles, Keith E

“…Dorsal column stimulation was undertaken in 10 patients referred to the Pain Relief Clinic for management of otherwise intractable angina pectoris. All…”
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Packaging and reverse transcription of snRNAs by retroviruses may generate pseudogenes by Giles, Keith E, Caputi, Massimo, Beemon, Karen L

“…Retroviruses specifically package two copies of their RNA genome in each viral particle, along with some small cellular RNAs, including tRNAs and 7S L RNA. We…”
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Solution structure of the pseudo-5' splice site of a retroviral splicing suppressor by Cabello-Villegas, Javier, Giles, Keith E, Soto, Ana Maria, Yu, Ping, Mougin, Annie, Beemon, Karen L, Wang, Yun-Xing

“…Control of Rous sarcoma virus RNA splicing depends in part on the interaction of U1 and U11 snRNPs with an intronic RNA element called the negative regulator…”
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An analysis of the epigenetic basis of Argonaute 2 function at DNA repetitive sequences in human cells by Giles, Keith E, Lefevre, Gaelle, Felsenfeld, Gary

“…To explore the role of RNAi –dependent mechanisms in maintaining heterochromatic structures in vertebrates, we have determined the distribution of binding…”
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Maintenance of a Vertebrate Constitutive Heterochromatin Domain by a Dicer-dependent Mechanism by Giles, Keith E., Ghirlando, Rodolfo, Felsenfeld, Gary

“…The 16 kb heterochromatin domain between the chicken β-globin locus and the folate receptor gene is used here to study the roles of RNA dependent mechanisms…”
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Rous sarcoma virus RNA: Splicing suppression and pseudogene formation by Giles, Keith E

“…Rous sarcoma virus generates three RNA species. A fraction of the unspliced primary transcripts are singly spliced. The maintenance of unspliced RNA is…”
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Intractable angina pectoris: management with dorsal column stimulation by Murphy, D F, Giles, K E

“…This case report gives the first published description of the use of dorsal column stimulation in the management of a patient with intractable angina pectoris…”
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Herpes zoster and cimetidine

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