Search Results - "Giles, K M"

Glucocorticoid-mediated regulation of granulocyte apoptosis and macrophage phagocytosis of apoptotic cells: implications for the resolution of inflammation by Heasman, SJ, Giles, KM, Ward, C, Rossi, AG, Haslett, C, Dransfield, I

“…Glucocorticoids represent one of the most effective clinical treatments for a range of inflammatory conditions, including severe acute inflammation. Although…”
Get full text

A death-domain-containing receptor that mediates apoptosis by Kitson, Jeremy, Raven, Thomas, Jiang, Ying-Ping, Goeddel, David V, Giles, Katharine M, Pun, Kwok-Tao, Grinham, Christine J, Brown, Robin, Farrow, Stuart N

“…The cell-killing effects of the cytokines TNF-alpha and FasL are mediated by the distinct cell-surface receptors TNFR1, TNFR2 and Fas (also known as…”
Get full text

Glucocorticoid Augmentation of Macrophage Capacity for Phagocytosis of Apoptotic Cells Is Associated with Reduced p130Cas Expression, Loss of Paxillin/pyk2 Phosphorylation, and High Levels of Active Rac by Giles, Katherine M, Ross, Katherine, Rossi, Adriano G, Hotchin, Neil A, Haslett, Christopher, Dransfield, Ian

“…Phagocytic clearance of apoptotic granulocytes has a pivotal role in determining an inflammatory outcome, resolution or progression to a chronic state…”
Get full text

Anti-CTLA4 toxicity associates with genetic variation correlating with serum antibody diversity by Simpson, D., Ferguson, R., Gowen, M., Giles, K.M., Tchack, J., Zhou, H., Moran, U., Dawood, Z., Pavlick, A., Hu, S., Wilson, M.A., Zhong, H., Krogsgaard, M., Weber, J.S., Osman, I., Kirchhoff, T.

Get full text

Preexposure to amphetamine and nicotine predisposes rats to self-administer a low dose of cocaine by HORGER, B. A, GILES, M. K, SCHENK, S

“…The acquisition of low-dose (0.25 mg/kg/infusion) intravenous cocaine self-administration was measured in rats that had received nine daily injections of…”
Get full text

AN APPETITE FOR APOPTOTIC CELLS? CONTROVERSIES AND CHALLENGES by Giles, Katherine M., Hart, Simon P., Haslett, Christopher, Rossi, Adriano G., Dransfield, Ian

Get full text

Numb Inhibits Membrane Localization of Sanpodo, a Four-Pass Transmembrane Protein, to Promote Asymmetric Divisions in Drosophila by O'Connor-Giles, Kate M., Skeath, James B.

“…Cellular diversity is a fundamental characteristic of complex organisms, and the Drosophila CNS has proved an informative paradigm for understanding the…”
Get full text

MRNA stability and the control of gene expression: implications for human disease by Hollams, Elysia M, Giles, Keith M, Thomson, Andrew M, Leedman, Peter J

“…Regulation of gene expression is essential for the homeostasis of an organism, playing a pivotal role in cellular proliferation, differentiation, and response…”
Get full text

Novel Binding of HuR and Poly(C)-binding Protein to a Conserved UC-rich Motif within the 3′-Untranslated Region of the Androgen Receptor Messenger RNA by Yeap, Bu B., Voon, Dominic C., Vivian, Julian P., McCulloch, Ross K., Thomson, Andrew M., Giles, Keith M., Czyzyk-Krzeska, Maria F., Furneaux, Henry, Wilce, Matthew C.J., Wilce, Jackie A., Leedman, Peter J.

“…The androgen receptor (AR) mediates androgen action and plays a central role in the proliferation of specific cancer cells. We demonstrated recently that AR…”
Get full text

1182PAnti-CTLA4 toxicity associates with genetic variation correlating with serum antibody diversity by Simpson, D, Ferguson, R, Gowen, M, Giles, K M, Tchack, J, Zhou, H, Moran, U, Dawood, Z, Pavlick, A, Hu, S, Wilson, M A, Zhong, H, Krogsgaard, M, Weber, J S, Osman, I, Kirchhoff, T

Get full text

Halogenated 4-(Phenoxymethyl)piperidines as Potential Radiolabeled Probes for σ-1 Receptors:  In Vivo Evaluation of [123I]-1-(Iodopropen-2-yl)-4-[(4-cyanophenoxy)methyl]piperidine by Waterhouse, Rikki N, Mardon, Karine, Giles, Katrina M, Collier, T. Lee, O'Brien, Joanne C

“…Several halogenated 4-(4-phenoxymethyl)piperidines were synthesized as potential σ receptor ligands. The affinity and selectivity of these compounds were…”
Get full text

Retroelements and segmental duplications in the generation of diversity within the MHC by Gaudieri, S, Kulski, J K, Balmer, L, Giles, K M, Inoko, H, Dawkins, R L

Get more information

Duplication and polymorphism in the MHC: Alu generated diversity and polymorphism within the PERB11 gene family by Gaudieri, S, Giles, K M, Kulski, J K, Dawkins, R L

“…The PERB11 gene family has at least five members within the telomeric region of the MHC. The PERB11.1 and PERB11.2 genes are approximately 40 kb and 160 kb…”
Get more information

Aberration tolerances for visual optical systems by Giles, M K

“…The effects of aberrations on images formed by a total system, including the eye, are assessed in terms of modulation threshold, grating detectability, and…”
Get more information

Academic sexual intimacy violations: Ethicality and occurrence reports from undergraduates by Skinner, Linda J., Giles, Melissa K., Griffith, Sue Ellen, Sonntag, Michael E., Berry, Kenneth K., Beck, Robert

“…Students at a state university (N = 583) and a nearby community college (N = 229) in a Southeastern state rated the ethicality and reported the occurrence of…”
Get full text

Glucocorticoid-mediated regulation of granulocyte apoptosis and macrophage phagocytosis of apoptotic cells: implications for the resolution of inflammation : Mechanisms of steroid action and resistance in inflammation by HEASMAN, S. J, GILES, K. M, WARD, C, ROSSI, A. G, HASLETT, C, DRANSFIELD, I

Get full text

A Real-Time Video Tracking System by Gilbert, Alton L., Giles, Michael K., Flachs, Gerald M., Rogers, Robert B., Hsun, U Yee

“…Object identification and tracking applications of pattern recognition at video rates is a problem of wide interest, with previous attempts limited to very…”
Get full text

The 3'-Untranslated Region of p21 super(WAF1) mRNA Is a Composite cis-Acting Sequence Bound by RNA-binding Proteins from Breast Cancer Cells, Including HuR and Poly(C)-binding Protein by Giles, K M, Daly, J M, Beveridge, D J, Thomson, A M, Voon, D C, Furneaux, H M, Jazayeri, JA, Leedman, P J

“…Despite promoting growth in many cell types, epidermal growth factor (EGF) induces growth inhibition in a variety of cancer cells that overexpress its…”
Get full text

Interferon γ suppresses glucocorticoid augmentation of macrophage clearance of apoptotic cells by Heasman, Sarah J., Giles, Katherine M., Rossi, Adriano G., Allen, Judith E., Haslett, Christopher, Dransfield, Ian

“…One of beneficial effects of glucocorticoids (GC) in inflammation may be the augmentation of macrophages' capacity for phagocytosis of apoptotic cells, a…”
Get full text

Radioelectrophoretic patterns of aqueous and plasma: after intravenous injection of I 131-labeled insulin into rabbits by GILES, K M, HARRIS, J E

Get more information