Search Results - "Gileadi, O."

Tryptophan-Mediated Interactions between Tristetraprolin and the CNOT9 Subunit Are Required for CCR4-NOT Deadenylase Complex Recruitment by Bulbrook, D., Brazier, H., Mahajan, P., Kliszczak, M., Fedorov, O., Marchese, F.P., Aubareda, A., Chalk, R., Picaud, S., Strain-Damerell, C., Filippakopoulos, P., Gileadi, O., Clark, A.R., Yue, W.W., Burgess-Brown, N.A., Dean, J.L.E.

“…The zinc-finger protein tristetraprolin (TTP) binds to AU-rich elements present in the 3′ untranslated regions of transcripts that mainly encode proteins of…”
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Homozygous mutations in a predicted endonuclease are a novel cause of congenital dyserythropoietic anemia type I by Babbs, C., Roberts, N. A., Sanchez-Pulido, L., McGowan, S. J., Ahmed, M. R., Brown, J. M., Sabry, M. A., Bentley, D. R., McVean, G. A., Donnelly, P., Gileadi, O., Ponting, C. P., Higgs, D. R., Buckle, V. J.

“…The congenital dyserythropoietic anemias are a heterogeneous group of rare disorders primarily affecting erythropoiesis with characteristic morphological…”
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276 A Small Molecule Inhibitor of the BLM Helicase That Modulates Chromosome Stability in Human Cells by Dexheimer, T.S, Nguyen, G.H, Rosenthal, A.S, Bohr, V.A, Harris, C.C, Jadhav, A, Gileadi, O, Maloney, D.J, Simeonov, A, Hickson, I.D

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A prominent  -hairpin structure in the winged-helix domain of RECQ1 is required for DNA unwinding and oligomer formation by Lucic, B., Zhang, Y., King, O., Mendoza-Maldonado, R., Berti, M., Niesen, F. H., Burgess-Brown, N. A., Pike, A. C. W., Cooper, C. D. O., Gileadi, O., Vindigni, A.

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Purification and characterization of yeast RNA polymerase II transcription factor b by Feaver, W.J. (Stanford University School of Medicine, Stanford, CA), Gileadi, O, Kornberg, R.D

“…Heat treatment of yeast nuclear extracts abolished the capacity to initiate transcription at RNA polymerase 11 promoters. Activity was restored by the addition…”
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Screening and Production of Recombinant Human Proteins: Protein Production in E. coli by Burgess-Brown, Nicola A, Mahajan, Pravin, Strain-Damerell, Claire, Fernandez-Cid, Alejandra, Gileadi, Opher, Gräslund, Susanne

“…In Chapter 3 , we described the Structural Genomics Consortium (SGC) process for generating multiple constructs of truncated versions of each protein using…”
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Novel Dihydropteridinone Derivatives As Potent Inhibitors of the Understudied Human Kinases Vaccinia-Related Kinase 1 and Casein Kinase 1δ/ε by de Souza Gama, Fernando H., Dutra, Luiz A., Hawgood, Michael, dos Reis, Caio Vinícius, Serafim, Ricardo A. M., Ferreira, Marcos A., Teodoro, Bruno V. M., Takarada, Jéssica Emi, Santiago, André S., Balourdas, Dimitrios-Ilias, Nilsson, Ann-Sofie, Urien, Bruno, Almeida, Vitor M., Gileadi, Carina, Ramos, Priscila Z., Salmazo, Anita, Vasconcelos, Stanley N. S., Cunha, Micael R., Mueller, Susanne, Knapp, Stefan, Massirer, Katlin B., Elkins, Jonathan M., Gileadi, Opher, Mascarello, Alessandra, Lemmens, Bennie B. L. G., Guimarães, Cristiano R. W., Azevedo, Hatylas, Couñago, Rafael M.

“…Vaccinia-related kinase 1 (VRK1) and the δ and ε isoforms of casein kinase 1 (CK1) are linked to various disease-relevant pathways. However, the lack of tool…”
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Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM by Bashore, Frances M, Katis, Vittorio L, Du, Yuhong, Sikdar, Arunima, Wang, Dongxue, Bradshaw, William J, Rygiel, Karolina A, Leisner, Tina M, Chalk, Rod, Mishra, Swati, Williams, C Andrew, Gileadi, Opher, Brennan, Paul E, Wiley, Jesse C, Gockley, Jake, Cary, Gregory A, Carter, Gregory W, Young, Jessica E, Pearce, Kenneth H, Fu, Haian, Axtman, Alison D

“…RNA sequencing and genetic data support spleen tyrosine kinase (SYK) and high affinity immunoglobulin epsilon receptor subunit gamma (FCER1G) as putative…”
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Cloning of a subunit of yeast RNA polymerase II transcription factor b and CTD kinase by Gileadi, O. (Stanford University Medical School, Stanford, CA), Feaver, W.J, Kornberg, R.D

“…Yeast RNA polymerase II initiation factor b copurifies with three polypeptides of 85, 73, and 50 kilodaltons and with a protein kinase that phosphorylates the…”
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Yeast TFIIE. Cloning, expression, and homology to vertebrate proteins by Feaver, W J, Henry, N L, Bushnell, D A, Sayre, M H, Brickner, J H, Gileadi, O, Kornberg, R D

“…Genes encoding both the 66- and the 43-kDa subunits of yeast RNA polymerase II initiation factor a, designated TFA1 and TFA2, have been isolated. Both genes…”
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Transcription of the H19 gene in differentiating cytotrophoblasts from human placenta by Rachmilewitz, J, Gileadi, O, Eldar-Geva, T, Schneider, T, de-Groot, N, Hochberg, A

“…Placental differentiation is closely correlated with the appearance of specific proteins, yet factors regulating cytotrophoblast differentiation are unknown…”
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Development of a time-resolved fluorescence resonance energy transfer ultra-high throughput screening assay targeting SYK and FCER1G interaction by Du, Yuhong, Wang, Dongxue, Katis, Vittorio L., Zoeller, Elizabeth L., Qui, Min, Levey, Allan I., Gileadi, Opher, Fu, Haian

“…The spleen tyrosine kinase (SYK) and high affinity immunoglobulin epsilon receptor subunit gamma (FCER1G) interaction has a major role in the normal innate and…”
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Scanning Electron Microscopy of Cells and Tissues under Fully Hydrated Conditions by Thiberge, Stephan, Nechushtan, Amotz, Sprinzak, David, Gileadi, Opher, Behar, Vered, Zik, Ory, Chowers, Yehuda, Michaeli, Shulamit, Schlessinger, Joseph, Moses, Elisha, Kornberg, Roger D.

“…A capability for scanning electron microscopy of wet biological specimens is presented. A membrane that is transparent to electrons protects the fully hydrated…”
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FOXN1 forms higher-order nuclear condensates displaced by mutations causing immunodeficiency by Rota, Ioanna A, Handel, Adam E, Maio, Stefano, Klein, Fabian, Dhalla, Fatima, Deadman, Mary E, Cheuk, Stanley, Newman, Joseph A, Michaels, Yale S, Zuklys, Saulius, Prevot, Nicolas, Hublitz, Philip, Charles, Philip D, Gkazi, Athina Soragia, Adamopoulou, Eleni, Qasim, Waseem, Davies, Edward Graham, Hanson, Imelda, Pagnamenta, Alistair T, Camps, Carme, Dreau, Helene M, White, Andrea, James, Kieran, Fischer, Roman, Gileadi, Opher, Taylor, Jenny C, Fulga, Tudor, Lagerholm, B Christoffer, Anderson, Graham, Sezgin, Erdinc, Holländer, Georg A

“…The transcription factor FOXN1 is a master regulator of thymic epithelial cell (TEC) development and function. Here, we demonstrate that FOXN1 expression is…”
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Expressing the human proteome for affinity proteomics: optimising expression of soluble protein domains and in vivo biotinylation by Keates, Tracy, Cooper, Christopher D.O., Savitsky, Pavel, Allerston, Charles K., Phillips, Claire, Hammarström, Martin, Daga, Neha, Berridge, Georgina, Mahajan, Pravin, Burgess-Brown, Nicola A., Müller, Susanne, Gräslund, Susanne, Gileadi, Opher

“…The generation of affinity reagents to large numbers of human proteins depends on the ability to express the target proteins as high-quality antigens. The…”
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Direct Observation of RuvAB-Catalyzed Branch Migration of Single Holliday Junctions by Amit, Roee, Gileadi, Opher, Stavans, Joel, Bustamante, Carlos J.

“…Holliday junctions form during DNA repair and homologous recombination processes. These processes entail branch migration, whereby the length of two arms of a…”
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Compaction of Single DNA Molecules Induced by Binding of Integration Host Factor (IHF) by B. M. Jaffar Ali, Amit, Roee, Braslavsky, Ido, Oppenheim, Amos B., Gileadi, Opher, Stavans, Joel

“…We studied the interaction between the integration host factor (IHF), a major nucleoid-associated protein in bacteria, and single DNA molecules…”
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An Unusual Eukaryotic Protein Phosphatase Required for Transcription by RNA Polymerase II and CTD Dephosphorylation in S. cerevisiae by Kobor, Michael S, Archambault, Jacques, Lester, William, Holstege, Frank C.P, Gileadi, Opher, Jansma, David B, Jennings, Ezra G, Kouyoumdjian, Fiona, Davidson, Alan R, Young, Richard A, Greenblatt, Jack

“…The carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II is phosphorylated soon after transcriptional initiation. We show here that the…”
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Distinct Regions of MAT1 Regulate cdk7 Kinase and TFIIH Transcription Activities by Busso, Didier, Keriel, Anne, Sandrock, Björn, Poterszman, Arnaud, Gileadi, Opher, Egly, Jean-Marc

“…The transcription/DNA repair factor TFIIH may be resolved into at least two subcomplexes: the core TFIIH and the cdk-activating kinase (CAK) complex. The CAK…”
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Autophosphorylation restrains the apoptotic activity of DRP-1 kinase by controlling dimerization and calmodulin binding by Shani, Gidi, Henis-Korenblit, Sivan, Jona, Ghil, Gileadi, Opher, Eisenstein, Miriam, Ziv, Tamar, Admon, Arie, Kimchi, Adi

“…DRP‐1 is a pro‐apoptotic Ca2+/calmodulin (CaM)‐regulated serine/threonine kinase, recently isolated as a novel member of the DAP‐kinase family of proteins. It…”
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