Search Results - "Gildenberg, Melissa S."

Conformational flexibility of fork-remodeling helicase Rad5 shown by full-ensemble hybrid methods by Gildenberg, Melissa S, Washington, M Todd

“…Several pathways exist to bypass DNA damage during replication. One such pathway is template switching. The Rad5 protein plays two important roles in template…”
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Control of DNA Damage Bypass by Ubiquitylation of PCNA by Ripley, Brittany M, Gildenberg, Melissa S, Washington, M Todd

“…DNA damage leads to genome instability by interfering with DNA replication. Cells possess several damage bypass pathways that mitigate the effects of DNA…”
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Modeling Conformationally Flexible Proteins With X-ray Scattering and Molecular Simulations by Powers, Kyle T., Gildenberg, Melissa S., Washington, M. Todd

“…Proteins and protein complexes with high conformational flexibility participate in a wide range of biological processes. These processes include genome…”
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Structure of DNA polymerase ζ: capturing the getaway driver by Washington, M. Todd, Gildenberg, Melissa S.

“…During translesion synthesis, eukaryotic DNA polymerase ζ carries out extension from a wide range of DNA lesions. Elucidation of the cryo-EM structure of…”
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Fork-Remodeling Helicase Rad5 Preferentially Reverses Replication Forks with Gaps in the Leading Strand by Ling, Justin A., Gildenberg, Melissa S., Honda, Masayoshi, Kondratick, Christine M., Spies, Maria, Washington, M.Todd

“…[Display omitted] •Rad5 is a fork-reversal helicase required for template switching.•We monitored the kinetics of fork reversal using a FRET-based assay.•Rad5…”
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Amplification of Wild-Type RET Represents a Novel Molecular Subtype of Several Cancer Types With Clinical Response to Selpercatinib by Gandhi, Malini M, Ricciuti, Biagio, Harada, Guilherme, Repetto, Matteo, Gildenberg, Melissa S, Singh, Ankit, Li, Yvonne Y, Gagné, Andréanne, Wang, Xinan, Aizer, Ayal, Fitzgerald, Kelly, Nishino, Mizuki, Alessi, Joao, Pecci, Federica, Di Federico, Alessandro, Fisch, Adam, Drilon, Alexander, Nardi, Valentina, Sholl, Lynette, Awad, Mark M, Rotow, Julia

“…rearrangements and activating point mutations represent targetable genomic alterations in advanced solid tumors. However, the frequency and clinicopathologic…”
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Structure of DNA polymerase [zeta]: capturing the getaway driver by Washington, M. Todd, Gildenberg, Melissa S

“…During translesion synthesis, eukaryotic DNA polymerase [zeta] carries out extension from a wide range of DNA lesions. Elucidation of the cryo-EM structure of…”
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Modeling conformationally flexible proteins with X-ray scattering and molecular simulations by Gildenberg, Melissa S., Washington, M. Todd

“…Abstract only…”
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The Many Roles of PCNA in Eukaryotic DNA Replication by Boehm, E M, Gildenberg, M S, Washington, M T

“…Proliferating cell nuclear antigen (PCNA) plays critical roles in many aspects of DNA replication and replication-associated processes, including translesion…”
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SAT588 Cushing’s Syndrome Due To Ectopic ACTH Secretion From Ovarian Teratomas by Kang, Yu Mi, Gildenberg, Melissa S, Quade, Bradley J, Blair, Rachel A

“…Abstract Disclosure: Y. Kang: None. M.S. Gildenberg: None. B.J. Quade: None. R.A. Blair: None. Background: Approximately 9-18% of Cushing’s syndrome (CS) cases…”
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Modeling Conformationally Flexible Proteins With X-ray Scattering and Molecular Simulations by Powers, Kyle T., Gildenberg, Melissa S., Washington, M. Todd

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