Search Results - "Gildea, A."

Relationship of CD86 surface marker expression and cytotoxicity on dendritic cells exposed to chemical allergen by Hulette, Ben C., Ryan, Cindy A., Gildea, Lucy A., Gerberick, G. Frank

“…Human peripheral blood-derived dendritic cells (DC) respond to a variety of chemical allergens by up-regulating expression of the co-stimulatory molecule CD86…”
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Early weaning is related to weight and rate of weight gain in infancy by Sloan, S., Gildea, A., Stewart, M., Sneddon, H., Iwaniec, D.

“…Background  Evidence relating to the effect of early weaning on infant weight and weight gain is conflicting. The aim of this paper is to compare weight and…”
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Transcript-specific determinants of pre-mRNA splicing revealed through in vivo kinetic analyses of the 1st and 2nd chemical steps by Gildea, Michael A., Dwyer, Zachary W., Pleiss, Jeffrey A.

“…We generate high-precision measurements of the in vivo rates of both chemical steps of pre-mRNA splicing across the genome-wide complement of substrates in…”
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Histoplasma capsulatum Yeasts Are Phagocytosed Via Very Late Antigen-5, Killed, and Processed for Antigen Presentation by Human Dendritic Cells by Gildea, Lucy A, Morris, Randal E, Newman, Simon L

“…Histoplasma capsulatum (Hc) is a facultative, intracellular parasite of world-wide importance. As the induction of cell-mediated immunity to Hc is of critical…”
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Human Dendritic Cell Activity against Histoplasma capsulatum Is Mediated via Phagolysosomal Fusion by Gildea, Lucy A, Ciraolo, Georgianne M, Morris, Randal E, Newman, Simon L

“…Histoplasma capsulatum is a fungal pathogen that requires the induction of cell-mediated immunity (CMI) for host survival. We have demonstrated that human…”
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Long noncoding RNA CHROMR regulates antiviral immunity in humans by van Solingen, Coen, Cyr, Yannick, Scacalossi, Kaitlyn R., de Vries, Maren, Barrett, Tessa J., de Jong, Annika, Gourvest, Morgane, Zhang, Tracy, Peled, Daniel, Kher, Raadhika, Cornwell, MacIntosh, Gildea, Michael A., Brown, Emily J., Fanucchi, Stephanie, Mhlanga, Musa M., Berger, Jeffrey S., Dittmann, Meike, Moore, Kathryn J.

“…Long noncoding RNAs (lncRNAs) have emerged as critical regulators of gene expression, yet their contribution to immune regulation in humans remains poorly…”
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A remote and highly conserved enhancer supports amygdala specific expression of the gene encoding the anxiogenic neuropeptide substance-P by DAVIDSON, S, MILLER, K. A, DOWELL, A, GILDEA, A, MACKENZIE, A

“…The neuropeptide substance P (SP), encoded by the preprotachykinin-A (PPTA) gene, is expressed in the central and medial amygdaloid nucleus, where it plays a…”
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Multiplexed primer extension sequencing: A targeted RNA-seq method that enables high-precision quantitation of mRNA splicing isoforms and rare pre-mRNA splicing intermediates by Gildea, Michael A., Dwyer, Zachary W., Pleiss, Jeffrey A.

“…•RNA-seq has enabled genome-wide studies of splicing mechanism and regulation.•Standard RNA-seq approaches poorly sample splicing informative loci.•MPE-Seq…”
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Dendritic cells and skin sensitization: Biological roles and uses in hazard identification by Ryan, Cindy A., Kimber, Ian, Basketter, David A., Pallardy, Marc, Gildea, Lucy A., Gerberick, G. Frank

“…Recent advances have been made in our understanding of the roles played by cutaneous dendritic cells (DCs) in the induction of contact allergy. A number of…”
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Gene expression changes in peripheral blood-derived dendritic cells following exposure to a contact allergen by Ryan, Cindy A., Gildea, Lucy A., Hulette, Ben C., Dearman, Rebecca J., Kimber, Ian, Gerberick, G.Frank

“…A critical step in the induction of allergic contact allergy is the activation and subsequent migration of Langerhans cells (LC), an important antigen…”
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Interactions of Contact Allergens with Dendritic Cells: Opportunities and Challenges for the Development of Novel Approaches to Hazard Assessment by Ryan, Cindy A., Gerberick, G. Frank, Gildea, Lucy A., Hulette, Ben C., Betts, Catherine J., Cumberbatch, Marie, Dearman, Rebecca J., Kimber, Ian

“…The identification of potential skin sensitizing chemicals is a key step in the overall skin safety risk assessment process. Traditionally, predictive testing…”
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Cellular co-expression of a LacZ marker gene driven by the amygdala-specific ECR1 enhancer with the substance P neuropeptide by Davidson, S, Miller, K A, Dowell, A, Gildea, A, MacKenzie, A

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Overexpression of Interleukin-4 in Lungs of Mice Impairs Elimination of Histoplasma capsulatum by GILDEA, Lucy A, GIBBONS, Reta, FINKELMAN, Fred D, DEEPE, George S

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Electrical Analysis of Wafer-to-Wafer Copper Hybrid Bonding at Sub-Micron Pitches by Ryan, K., Netzband, C., Gildea, A., Mimura, Y., Hoshino, S., LeFevre, S., Tuchman, A., Son, I., Aizawa, H., Maekawa, K.

“…Multi-level back-end-of-line (BEOL) test vehicles have been produced to evaluate the performance of the Tokyo Electron (TEL) wafer-to-wafer (W2W) bonding tool…”
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In vivo evidence for interferon-gamma-mediated homeostatic mechanisms in small intestine of the NHE3 Na+/H+ exchanger knockout model of congenital diarrhea by Woo, Alison L, Gildea, Lucy A, Tack, Leslie M, Miller, Marian L, Spicer, Zachary, Millhorn, David E, Finkelman, Fred D, Hassett, Daniel J, Shull, Gary E

“…Mice lacking NHE3, the major absorptive Na(+)/H(+) exchanger in the intestine, are the only animal model of congenital diarrhea. To identify molecular changes…”
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A new thermodynamic model describes the effects of ligand density and type, salt concentration and protein species in hydrophobic interaction chromatography by Deitcher, R.W., Rome, J.E., Gildea, P.A., O’Connell, J.P., Fernandez, E.J.

“…A new thermodynamic model is derived that describes both loading and pulse-response behavior of proteins in hydrophobic interaction chromatography (HIC). The…”
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Identification of Gene Expression Changes Induced by Chemical Allergens in Dendritic Cells: Opportunities for Skin Sensitization Testing by Gildea, Lucy A., Ryan, Cindy A., Foertsch, Leslie M., Kennedy, Jennifer M., Dearman, Rebecca J., Kimber, Ian, Gerberick, G. Frank

“…Cellular changes within resident skin dendritic cells (DCs) after allergen uptake and processing are critical events in the acquisition of skin sensitization…”
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Protocol: A randomised controlled trial evaluation of Cancer Focus NI’s ‘Dead Cool’ smoking prevention programme in post-primary schools by Dunne, L., Thurston, A., Gildea, A., Kee, F., Lazenbatt, A.

“…•This protocol outlines a trial of a smoking prevention programme in Northern Ireland.•Year 9 students completed a survey and carbon monoxide testing at three…”
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Examination of Phenotypic Changes in Peripheral Blood-Derived Dendritic Cells Following Exposure to a Contact Allergen: Cell Surface Marker and Gene Expression by Ryan, Cindy A., Hulette, Ben C., Gildea, Lucy A., Dearman, Rebecca J., Kimber, Ian, Gerberick, G. Frank

“…The evaluation of the potential to induce allergic contact dermatitis is an important component of the overall safety assessment process of a new chemical…”
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The Regional Representation of Federal Reserve Bank Presidents by Gildea, John A.

“…An ongoing debate has recently culminated in a number of lawsuits being filed questioning the constitutionality of having Federal Reserve Bank presidents serve…”
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