Search Results - "Gilboa, Dafna"
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Extrahepatic cholangiocyte obstruction is mediated by decreased glutathione, Wnt and Notch signaling pathways in a toxic model of biliary atresia
Published in Scientific reports (05-05-2020)“…Biliary atresia is a neonatal liver disease with extrahepatic bile duct obstruction and progressive liver fibrosis. The etiology and pathogenesis of the…”
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A machine learning model for early diagnosis of type 1 Gaucher disease using real-life data
Published in Journal of clinical epidemiology (01-11-2024)“…The diagnosis of Gaucher disease (GD) presents a major challenge due to the high variability and low specificity of its clinical characteristics, along with…”
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Erythropoietin enhances Kupffer cell number and activity in the challenged liver
Published in Scientific reports (04-09-2017)“…Erythropoietin (EPO) is the main hormone driving mammalian erythropoiesis, with activity mediated via the surface receptor, EPO-R, on erythroid progenitor…”
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Erythropoietin receptor in B cells plays a role in bone remodeling in mice
Published in Theranostics (01-01-2020)“…Erythropoietin (EPO) is a key regulator of erythropoiesis. However, EPO receptors (EPO-Rs) are also expressed on non-erythroid cell types, including myeloid…”
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Erythropoietin Mediated Increase in Monocyte-Derived Liver Macrophages; A Role for Kupffer Cells?
Published in Blood (03-12-2015)“…Erythropoietin (EPO) is the major hormone that drives mammalian erythropoiesis, via its surface receptor, EPO-R. It is mainly used for treating anemia…”
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Transdifferentiation of Bone Marrow Pro-B Cells into Bone-Resorbing Osteoclasts- an Unexpected Role for Erythropoietin
Published in Blood (02-12-2016)“…Bone turnover is regulated by the coupled actions of osteoblasts, the bone-forming cells, and monocyte-derived osteoclasts, which mediate bone resorption. B…”
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Recombinant Erythropoietin and Darbepoetin Alpha Exert a Similar Dose-Dependent Osteopenic Effect Which May Advocate for "Start Low, Go Slow" Dosing Strategy in Clinical Practice
Published in Blood (02-12-2016)“…Background and rationale: Identifying risk factors for bone loss is of utmost importance in the prevention of osteoporotic bone fractures. We and others have…”
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Liver Macrophages (Kupffer cells) As Novel Targets of Erythropoietin
Published in Blood (06-12-2014)“…Erythropoietin (EPO) synthesized by the kidney and by the fetal liver is the major hormone that drives mammalian erythropoiesis. It is thus used in treatment…”
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