Search Results - "Gilbert, Tamara J"

Salmonella Infection Drives Promiscuous B Cell Activation Followed by Extrafollicular Affinity Maturation by Di Niro, Roberto, Lee, Seung-Joo, Vander Heiden, Jason A., Elsner, Rebecca A., Trivedi, Nikita, Bannock, Jason M., Gupta, Namita T., Kleinstein, Steven H., Vigneault, Francois, Gilbert, Tamara J., Meffre, Eric, McSorley, Stephen J., Shlomchik, Mark J.

“…The B cell response to Salmonella typhimurium (STm) occurs massively at extrafollicular sites, without notable germinal centers (GCs). Little is known in terms…”
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Dysregulation of B Cell Repertoire Formation in Myasthenia Gravis Patients Revealed through Deep Sequencing by Vander Heiden, Jason A, Stathopoulos, Panos, Zhou, Julian Q, Chen, Luan, Gilbert, Tamara J, Bolen, Christopher R, Barohn, Richard J, Dimachkie, Mazen M, Ciafaloni, Emma, Broering, Teresa J, Vigneault, Francois, Nowak, Richard J, Kleinstein, Steven H, O'Connor, Kevin C

“…Myasthenia gravis (MG) is a prototypical B cell-mediated autoimmune disease affecting 20-50 people per 100,000. The majority of patients fall into two…”
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Inhibition of DYRK1A Stimulates Human β-Cell Proliferation by Dirice, Ercument, Walpita, Deepika, Vetere, Amedeo, Meier, Bennett C, Kahraman, Sevim, Hu, Jiang, Dančík, Vlado, Burns, Sean M, Gilbert, Tamara J, Olson, David E, Clemons, Paul A, Kulkarni, Rohit N, Wagner, Bridget K

“…Restoring functional β-cell mass is an important therapeutic goal for both type 1 and type 2 diabetes (1). While proliferation of existing β-cells is the…”
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A Small-Molecule Screening Strategy To Identify Suppressors of Statin Myopathy by Wagner, Bridget K, Gilbert, Tamara J, Hanai, Jun-ichi, Imamura, Shintaro, Bodycombe, Nicole E, Bon, Robin S, Waldmann, Herbert, Clemons, Paul A, Sukhatme, Vikas P, Mootha, Vamsi K

“…The reduction of plasma low-density lipoprotein levels by HMG-CoA reductase inhibitors, or statins, has had a revolutionary impact in medicine, but…”
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Large-scale chemical dissection of mitochondrial function by Mootha, Vamsi K, Wagner, Bridget K, Kitami, Toshimori, Gilbert, Tamara J, Peck, David, Ramanathan, Arvind, Schreiber, Stuart L, Golub, Todd R

“…Mitochondrial oxidative phosphorylation (OXPHOS) is under the control of both mitochondrial (mtDNA) and nuclear genomes and is central to energy homeostasis…”
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An Isochemogenic Set of Inhibitors To Define the Therapeutic Potential of Histone Deacetylases in β‑Cell Protection by Wagner, Florence F, Lundh, Morten, Kaya, Taner, McCarren, Patrick, Zhang, Yan-Ling, Chattopadhyay, Shrikanta, Gale, Jennifer P, Galbo, Thomas, Fisher, Stewart L, Meier, Bennett C, Vetere, Amedeo, Richardson, Sarah, Morgan, Noel G, Christensen, Dan Ploug, Gilbert, Tamara J, Hooker, Jacob M, Leroy, Mélanie, Walpita, Deepika, Mandrup-Poulsen, Thomas, Wagner, Bridget K, Holson, Edward B

“…Modulation of histone deacetylase (HDAC) activity has been implicated as a potential therapeutic strategy for multiple diseases. However, it has been difficult…”
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Small-Molecule Fluorophores To Detect Cell-State Switching in the Context of High-Throughput Screening by Wagner, Bridget K, Carrinski, Hyman A, Ahn, Young-Hoon, Kim, Yun Kyung, Gilbert, Tamara J, Fomina, Dina A, Schreiber, Stuart L, Chang, Young-Tae, Clemons, Paul A

“…A small molecule capable of distinguishing the distinct states resulting from cellular differentiation would be of enormous value, for example, in efforts…”
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Corrigendum: Large-scale chemical dissection of mitochondrial function by Wagner, Bridget K, Kitami, Toshimori, Gilbert, Tamara J, Peck, David, Ramanathan, Arvind, Schreiber, Stuart L, Golub, Todd R, Mootha, Vamsi K

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Inhibition of DYRK1A Stimulates Human [Beta]-Cell Proliferation by Dirice, Ercument, Walpita, Deepika, Vetere, Amedeo, Meier, Bennett C, Kahraman, Sevim, Hu, Jiang, Dancík, Vlado, Burns, Sean M, Gilbert, Tamara J, Olson, David E, Clemons, Paul A, Kulkarni, Rohit N, Wagner, Bridget K

“…Restoring functional β-cell mass is an important therapeutic goal for both type 1 and type 2 diabetes (1). While proliferation of existing β-cells is the…”
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Large-scale chemical dissection of mitochondrial function by Wagner, Bridget K, Kitami, Toshimori, Gilbert, Tamara J, Peck, David, Ramanathan, Arvind, Schreiber, Stuart L, Golub, Todd R, Mootha, Vamsi K

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Erratum: Corrigendum: Large-scale chemical dissection of mitochondrial function by Wagner, Bridget K, Kitami, Toshimori, Gilbert, Tamara J, Peck, David, Ramanathan, Arvind, Schreiber, Stuart L, Golub, Todd R, Mootha, Vamsi K

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Correction: Corrigendum: Large-scale chemical dissection of mitochondrial function by Wagner, Bridget K, Kitami, Toshimori, Gilbert, Tamara J, Peck, David, Ramanathan, Arvind, Schreiber, Stuart L, Golub, Todd R, Mootha, Vamsi K

“…Nat. Biotechnol. 26, 343–351 (2008); published online 24 February 2008; corrected after print 8 July 2008 In the version of this article initially published,…”
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