Search Results - "Gilbert, R.E"
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SGLT-2 inhibition in patients with kidney disease
Published in Diabetes & metabolism (01-12-2014)“…Abstract Accustomed to managing diabetes with agents that mostly act by modulating the secretion and actions of insulin, with the advent of sodium-glucose…”
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Outcome of meniscal repair prior compared with concurrent ACL reconstruction
Published in The knee (01-08-2012)“…Abstract Meniscal tears are commonly associated with traumatic rupture of the anterior cruciate ligament (ACL). At our centre, if a patient presents with…”
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Advanced glycation end products decrease mesangial cell MMP-7: A role in matrix accumulation in diabetic nephropathy?
Published in Kidney international (01-08-2007)“…Increased extracellular matrix material is a pathological hallmark of diabetic nephropathy. In addition to collagens, a variety of non-collagenous…”
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Proteomic Analysis of a Rodent Model of Heart Failure With Preserved Ejection Fraction - the Goto Kakizaki Rat
Published in Canadian journal of cardiology (01-10-2013)Get full text
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White on white meniscal tears to fix or not to fix?
Published in The knee (01-08-2010)“…Abstract The mechanical disadvantage to articular cartilage following meniscectomy has been well documented in the literature. Meniscal repair in the avascular…”
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Tranilast attenuates connective tissue growth factor-induced extracellular matrix accumulation in renal cells
Published in Kidney international (01-03-2006)“…Tranilast (N-[3,4-dimethoxycinnamoyl]anthranilic acid) is a synthetic compound that we have recently reported to inhibit transforming growth factor-β1…”
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Combination angiotensin converting enzyme and direct renin inhibition in heart failure following experimental myocardial infarction
Published in Cardiovascular therapeutics (01-04-2013)“…Diminishing the activity of the renin-angiotensin system (RAS) plays a pivotal role in the treatment of heart failure. In addition to angiotensin converting…”
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776 DPP-4 Inhibition Improves Cardiac Function Following Experimental Myocardial Infarction: Potential Non-Glp-1 Mediated Effects
Published in Canadian journal of cardiology (01-09-2012)Get full text
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The St. Leger total knee replacement
Published in The knee (01-10-2009)“…Abstract The St. Leger total knee replacement (Zynergy Orthopaedics Ltd, Rotherham, UK) was developed as a cheaper alternative to similar implants of its time…”
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287 Early outgrowth cell secretory products attenuate cardio-renal injury in a model of chronic kidney disease
Published in Canadian journal of cardiology (01-09-2011)Get full text
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723 Dpp-4 Inhibition attenuates cardiac dysfunction and adverse remodelling following myocardial infarction in experimental diabetes
Published in Canadian journal of cardiology (01-09-2011)Get full text
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Tranilast reduces mesenteric vascular collagen deposition and chymase-positive mast cells in experimental diabetes
Published in Journal of diabetes and its complications (01-09-2004)“…The mast cell has a central role in the pathogenesis of fibrosis a common feature of diabetic microvascular complications. Increased mast cell numbers have…”
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P1-55 Two ocular disease genes are epigentically modified and associated with congenital toxoplasmosis
Published in Early human development (2007)Get full text
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Microalbuminuria: prognostic and therapeutic implications in diabetes mellitus
Published in Diabetic medicine (01-08-1994)“…Thirty years following the development of the first radioimmunoassay for albumin, microalbuminuria is widely acknowledged as an important predictor of overt…”
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Changes in clinical indications for community antibiotic prescribing for children in the UK from 1996 to 2006: will the new NICE prescribing guidance on upper respiratory tract infections just be ignored?
Published in Archives of disease in childhood (01-05-2009)“…Objective:To analyse changes in clinical indications for community antibiotic prescribing for children in the UK between 1996 and 2006 and relate these…”
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Prediction of congenital toxoplasmosis by polymerase chain reaction analysis of amniotic fluid
Published in BJOG : an international journal of obstetrics and gynaecology (01-05-2005)“…Objective To determine the accuracy of polymerase chain reaction (PCR) analysis of amniotic fluid for fetal toxoplasmosis according to clinical predictors of…”
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Treating Ocular Toxoplasmosis - Current Evidence
Published in Memórias do Instituto Oswaldo Cruz (01-03-2009)“…The current treatment of ocular toxoplasmosis is controversial. The mainstay of treatment has been pyrimethamine and sulphonamides with or without systemic…”
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Combination therapy with tranilast and angiotensin-converting enzyme inhibition provides additional renoprotection in the remnant kidney model
Published in Kidney international (01-06-2006)“…Despite current therapy with agents that block the renin–angiotensin system, renal dysfunction continues to progress in a significant proportion of patients…”
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